Results 141 to 150 of about 1,044,497 (378)

Identifying the Risk Factors for Orbital Complications in Isolated Sphenoid Rhinosinusitis

Medicina
Background and Objectives: Isolated sphenoid rhinosinusitis may have devastating consequences such as orbital complications due to its anatomical contiguity with vital structures.
Shiaw-Yu Chang, Chi-Che Huang, Yu-Hsi Fan, Pei-Wen Wu, Ta-Jen Lee, Po-Hung Chang, Chien-Chia Huang   +6 more
doaj   +1 more source

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source

Orbital amelanotic melanoma in xeroderma pigmentosum: A rare association

Indian Journal of Ophthalmology, 2008
Xeroderma pigmentosum (XP) is an autosomal recessive genetic disorder of DNA repair in which the body′s normal ability to repair damage caused by ultraviolet light is deficient.
Rizvi Syed, Amitava Abadan, Mehdi Ghazala, Sharma Rajeev, Alam Mohammad   +4 more
doaj  

Engineered Mesenchymal Stem Cell–NK Cell Complexes for Spatially Targeted and Functionally Revitalized Cancer Immunotherapy

Advanced Science, EarlyView.
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang, Bo Yin, Munaiwaier Sabier, Youlan Yang, Mengling Wu, Zhouping Zhao, Xuanzhi Luo, Yuehong Zhong, Xiuming Zhu, Jie Zhang, Jing Wang, Kai Chen, Fei Ruan, Wei Zhang, Zhimin Lu, Jiong Wang   +15 more
wiley   +1 more source

Post-traumatic cutaneous meningioma. [PDF]

, 2004
Cutaneous meningiomas are extremely rare tumours and their diagnosis is difficult. We describe the case of a patient who developed a paranasal swelling after head trauma and associated fractures in the same region years before.
Borggreven, P.A., Graaf, F.H. de, Leemans, C.R., Valk, P. van der   +3 more
core  

Diagnostic ophthalmology. Orbital neoplasm (primary or secondary).

The Canadian veterinary journal = La revue veterinaire canadienne, 2005
Cheryl L, Cullen, Elisabeth, Snead, Bruce H, Grahn   +2 more
openaire   +3 more sources

Cinnamic‐Hydroxamic‐Acid Derivatives Exhibit Antibiotic, Anti‐Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid‐Associated Protein HU

Advanced Science, EarlyView.
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen, Yingqi Xu, Zhaoping Xiong, Hongliang Wang, Xin Wang, Yue Kang, Zhonglin Wang, Xiaoyan Zeng, Yahui Liu, Yehuan Zheng, Wei Chen, Mengzhe Li, Zhenyue Hu, Chi Xu, Yue Wu, Yawen Wang, Zuyi Yuan, Shuai Yuan, Huadong Liu, Steve Matthews, Nan Qiao, Yan Li, Bing Liu   +22 more
wiley   +1 more source

Orbital Aspergillosis or Giant Cell Arteritis — A Diagnostic Dilemma

Proceedings of Singapore Healthcare, 2013
Orbital aspergillosis is an uncommon but potentially fatal disease. Its initial clinical presentation can be nonspecific and may be easily confused with other systemic diseases (such as neoplasms, other orbital infections which could include bacterial ...
Hassan Ali MBBS (Pakistan), MRCP (Ireland), MRCPS (Glasgow), FCPS (Pakistan), Nai Lee Lui MBBS (Singapore), MMed (Int Med) Singapore, MRCP (UK), FAMS (Rheumatology), Parag R Salkade FRCR, MMed (Diagnostic Radiology), P Chandra Mohan MBBS, FRCR, MMed (Diagnostic Radiology), FAMS (Radiology), Pushpalatha Bangalore Lingegowda MBBS, MD (USA), York Kiat Tan MBBS (Singapore), MRCP (UK), MMed (Internal Med) Singapore   +5 more
doaj   +1 more source

PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites

Advanced Science, EarlyView.
This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang, Qian Shen, Yao Lin, Jing Zhu, Xiaolan Zhu, Rui Huang, Yijia Wu, Feiyang Shen, Qian Li, Guopei Zheng, Zhe Zhang, Qian Chu, Junhao Hu, Jianfeng Shen   +13 more
wiley   +1 more source

Giant Solitary Fibrous Tumour of The Orbit Resected via Subconjunctival Approach

Atatürk Üniversitesi Tıp Fakültesi Cerrahi Tıp Bilimleri Dergisi
Solitary fibrous tumours (SFTs) are uncommon neoplasms originating primarily in the pleura but occasionally in the orbit. Despite their generally benign nature, they can exhibit aggressive behaviour.
Mete Zeynal
doaj   +1 more source