Results 91 to 100 of about 393,980 (293)

Individual‐specific resting‐state networks predict language dominance in drug‐resistant epilepsy

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to reliably estimate individual‐specific resting‐state cortical networks and determine whether language network topography can predict task‐based language dominance in drug‐resistant epilepsy. Methods We utilized a multisession hierarchical Bayesian model (MS‐HBM) trained on drug‐resistant epilepsy patients ...
Mervyn Jun Rui Lim, Shaoshi Zhang, Shreya Pande, Aihuiping Xue, Ru Kong, Kareem Zaghloul, Sara Inati, B. T. Thomas Yeo   +7 more
wiley   +1 more source

Absence of Spatial Tuning in the Orbitofrontal Cortex

PLoS ONE, 2014
There is limited data in the literature to explicitly support the notion that neurons in OFC are truly action-independent in their coding. We set out to specifically test the hypothesis that OFC value-related neurons in area 13 m of the monkey do not carry information about the action required to obtain that reward--that activity in this area ...
Lauren E Grattan, Paul W Glimcher
openaire   +4 more sources

Orbitofrontal Cortex Pathology in Alzheimer's Disease [PDF]

Cerebral Cortex, 2000
The orbitofrontal cortex has been examined in Alzheimer's disease (AD) from the viewpoint of neurofibrillary tangle (NFT) pathology, its laminar distribution and topography. NFT pathology in the orbitofrontal cortex is extensive in AD. In cases with extensive cortical pathology, NFTs extend from the pole of the frontal lobe to the orbitoinsular ...
G W, Van Hoesen, J, Parvizi, C C, Chu
openaire   +2 more sources

Mindfulness meditation increases interictal epileptiform discharges in meditation‐naïve surgical epilepsy patients

Epilepsia, EarlyView.
Abstract Objective Meditation has widely recognized psychological and neuromodulatory benefits, yet its effects on epileptiform activity remain unclear. This study examined whether novice meditation modulates interictal epileptiform discharges (IEDs) in patients with drug‐resistant epilepsy using intracranial electroencephalography (iEEG).
Shweta Soni, Karine Brochu, Paolo Federico, Walter Hader, Julia W. Y. Kam, Fady Girgis   +5 more
wiley   +1 more source

16p11 Duplication Disrupts Hippocampal-Orbitofrontal-Amygdala Connectivity, Revealing a Neural Circuit Endophenotype for Schizophrenia

Cell Reports, 2020
Summary: Chromosome 16p11.2 duplications dramatically increase risk for schizophrenia, but the mechanisms remain largely unknown. Here, we show that mice with an equivalent genetic mutation (16p11.2 duplication mice) exhibit impaired hippocampal ...
Greg C. Bristow, David M. Thomson, Rebecca L. Openshaw, Emma J. Mitchell, Judith A. Pratt, Neil Dawson, Brian J. Morris   +6 more
doaj   +1 more source

Complementary predictive value of electromagnetic source imaging and hemodynamic responses in epilepsy surgery: A quantitative spatial analysis

Epilepsia, EarlyView.
Abstract Objective Accurate presurgical evaluation should assess not only the location but also the spatial extent of epileptic activity relative to the surgical cavity, a practical approximation of the epileptogenic zone. We evaluated how electromagnetic source imaging (EMSI) and hemodynamic responses to epileptic discharges relate to the surgical ...
Chifaou Abdallah, Edouard Delaire, Arielle Dascal, Aura González, Zhengchen Cai, Tanguy Hedrich, Hassan Khajehpour, Satoru Ikemoto, Masataka Tanaka, Boris C. Bernhardt, Eliane Kobayashi, Jean Gotman, Birgit Frauscher, Christophe Grova   +13 more
wiley   +1 more source

Visual functions of the orbitofrontal cortex

, 2015
The primate orbitofrontal cortex receives inputs directly from the inferior temporal visual cortex. The orbitofrontal cortex contains visual neurons that learn in one trial which visual object is associated with a reward such as a taste and represent ...
E.T. Rolls, Rolls, Edmund T.
core   +1 more source

Electroclinical features and dynamic network connectivity of orbitofrontal epilepsy

Epilepsia, EarlyView.
Abstract Objective Orbitofrontal epilepsy (OFE) is rare and underrecognized. This study aims to characterize electroclinical features and dynamic network connectivity of OFE and subtypes. Methods We retrospectively analyzed 17 patients with OFE who underwent stereoelectroencephalographic (SEEG) electrode implantation and epilepsy surgery at our center.
Meixuan Ren, Cuiping Xu, Na Clara Pan, Runshi Gao, Wei Shu, Xueyuan Wang, Xi Zhang, Li Wang, Liping Zhang, Xiaoming Yan, Xiaohua Zhang, Tao Yu, Mohamad Z Koubeissi, Yuping Wang   +13 more
wiley   +1 more source

Clinical significance of subclinical seizures in epilepsy presurgical evaluation: A systematic review and meta‐analysis

Epilepsia, EarlyView.
Abstract Objective Subclinical seizures (SCSs) remain an understudied aspect of presurgical evaluation in patients with drug‐resistant epilepsy (DRE), with uncertain prevalence, distribution among epilepsy types, and predictive value for surgical outcomes.
Pilar Bosque‐Varela, Panagiota‐Eleni Tsalouchidou, Petra Levicka, Lara Wadi, Elizabeth R. Blackwood, Eugen Trinka, Birgit Frauscher   +6 more
wiley   +1 more source

MPH-Induced Changes in Right Frontal Metabolism

Pediatric Neurology Briefs, 1999
The effects of methylphenidate (MPH), a drug that increases dopamine, on brain glucose metabolism in 20 cocaine abusers was studied using PET scans and measurements of D2 receptors at the Brookhaven National Laboratory, the State University of New York ...
J Gordon Millichap
doaj   +1 more source