Results 111 to 120 of about 393,980 (293)

Transcriptional signatures of cortical morphometric variability in temporal lobe epilepsy

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Widespread cognitive deficits in temporal lobe epilepsy (TLE) are associated with macroscale brain structural changes. However, the correlation between the changes in the cortical morphological similarity of the TLE and gene expression remains unclear.
Yaping Dong   +5 more
wiley   +1 more source

The Orbitofrontal Cortex Gray Matter Is Associated With the Interaction Between Insomnia and Depression

open access: yesFrontiers in Psychiatry, 2018
Insomnia and depression are highly comorbid symptoms in both primary insomnia (PI) and major depressive disorder (MDD). In the current study, we aimed at exploring both the homogeneous and heterogeneous brain structure alteration in PI and MDD patients ...
Siyi Yu   +9 more
doaj   +1 more source

Orbitofrontal cortex volume and brain reward response in obesity [PDF]

open access: yes, 2015
Background/objectivesWhat drives overconsumption of food is poorly understood. Alterations in brain structure and function could contribute to increased food seeking.
Shott, ME   +6 more
core   +1 more source

Quantifying extra‐lesional interhemispheric cortical asymmetry in focal cortical dysplasia type II

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Focal cortical dysplasia type II (FCDII) is a cortical malformation representing a common cause of surgically treatable drug‐resistant epilepsy. We studied whether FCDII disrupts normal structural interhemispheric asymmetry beyond the lesion location and quantified these asymmetries derived from structural magnetic resonance imaging (
Faezeh Heidari   +3 more
wiley   +1 more source

Neuroanatomical and functional correlates in borderline personality disorder: A narrative review

open access: yesIbrain, Volume 11, Issue 1, Page 19-31, Spring 2025.
Borderline personality disorder (BPD) is considered a dysfunctional, stable, and pervasive alteration in personality functioning with the inability to adapt to the environment, mental rigidity, and ego‐syntonic, and like all personality disorders is a consistent pattern of inner experience and behavior that deviates markedly from the expectations of ...
Giulio Perrotta
wiley   +1 more source

Borderline personality disorder, impulsivity, and the orbitofrontal cortex.

open access: yes, 2005
OBJECTIVE: Orbitofrontal cortex lesions produce disinhibited or socially inappropriate behavior and emotional irregularities. Characteristics of borderline personality disorder include impulsivity and affective instability.
Iversen, SD   +3 more
core   +1 more source

Increased functional connectivity of the posterior cingulate cortex with the lateral orbitofrontal cortex in depression [PDF]

open access: yes, 2018
To analyze the functioning of the posterior cingulate cortex (PCC) in depression, we performed the first fully voxel-level resting state functional-connectivity neuroimaging analysis of depression of the PCC, with 336 patients with major depressive ...
Peng Xie   +25 more
core   +1 more source

Human biomarker navigator

open access: yesiMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li   +29 more
wiley   +1 more source

The olfactory thalamus: unanswered questions about the role of the mediodorsal thalamic nucleus in olfaction

open access: yesFrontiers in Neural Circuits, 2015
The mediodorsal thalamic nucleus (MDT) is a higher order thalamic nucleus and its role in cognition is increasingly well established. Interestingly, components of the MDT also have a somewhat unique sensory function as they link primary olfactory cortex ...
Emmanuelle eCourtiol   +3 more
doaj   +1 more source

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