Results 11 to 20 of about 46,771 (232)
BackgroundSchizophrenia (SZ) is associated with the highest disability rate among serious mental disorders. Excited symptoms are the core symptoms of SZ, which appear in the early stage, followed by other stages of the disease subsequently.
Congxin Chen +7 more
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The orbitofrontal cortex and response selection [PDF]
Orbitofrontal cortex (OFC) function is often characterized in terms of stimulus–reward mapping; however, more recent evidence suggests that the OFC may play a role in selecting and representing extended actions. First, previously encoded reward associations in the OFC could be used to inform responding in novel but similar situations.
James J, Young, Matthew L, Shapiro
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Encoding touch and the orbitofrontal cortex [PDF]
AbstractLesion studies on nonhuman primates utilizing recognition memory tests have shown that the orbitofrontal cortex is critical for the encoding of novel information, and anatomical studies have shown that the orbitofrontal cortex forms part of a mnemonic circuit that connects limbic medial temporal areas with higher‐order lateral frontal cortical ...
Stephen, Frey +2 more
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The stressed orbitofrontal cortex.
Stressor exposure causes dendritic remodeling on excitatory neurons in multiple regions of the brain, including the orbitofrontal cortex (OFC). Additionally, stressor and exogenous stress hormone exposure impair cognitive functions that are dependent on the OFC.
Michelle K. Sequeira, Shannon L. Gourley
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Chronic tinnitus, the continuous perception of a phantom sound, is a highly prevalent audiological symptom, for which the underlying pathology has not yet been fully understood.
Linda Becker +3 more
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Orbitofrontal Cortex and Memory Formation [PDF]
Which one of the many regions of the anatomically heterogeneous prefrontal cortex is part of the critical core of the neural circuit for encoding? This positron emission tomography (PET) experiment measured changes in cerebral blood flow (CBF) in normal human participants during the presentation of abstract visual information in four conditions that ...
Frey, Stephen, Petrides, Michael
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Chemosensory Learning in the Cortex
Taste is a primary reinforcer. Olfactory-taste and visual-taste association learning takes place in the primate including human orbitofrontal cortex to build representations of flavour.
Edmund eRolls
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The Orbitofrontal Cortex and Reward [PDF]
The primate orbitofrontal cortex contains the secondary taste cortex, in which the reward value of taste is represented. It also contains the secondary and tertiary olfactory cortical areas, in which information about the identity and also about the reward value of odors is represented. The orbitofrontal cortex also receives information about the sight
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Medial-lateral Organization of the Orbitofrontal Cortex [PDF]
Abstract Emerging evidence suggests that specific cognitive functions localize to different subregions of OFC, but the nature of these functional distinctions remains unclear. One prominent theory, derived from human neuroimaging, proposes that different stimulus valences are processed in separate orbital regions, with medial and lateral
Erin L. Rich, Jonathan D. Wallis
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Altered sulcogyral patterns of orbitofrontal cortex in a large cohort of patients with schizophrenia
Abnormalities in prenatal brain development contribute to schizophrenia vulnerability. Orbitofrontal cortex sulcogyral patterns are largely determined during prenatal development, and four types of orbitofrontal cortex sulcogyral patterns have been ...
Shuichi Isomura +10 more
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