Results 11 to 20 of about 48,406 (242)
Current Biology, 2018 The orbitofrontal cortex is a large and heterogeneous cortical area on the ventral surface of the frontal lobe and is intimately involved in emotion and executive function. In this Primer, Peter Rudebeck and Erin Rich summarize our understanding of the mechanisms through which orbitofrontal cortex adaptively shapes decision making and affective ...
Peter H, Rudebeck, Erin L, Rich
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The State of the Orbitofrontal Cortex [PDF]
Neuron, 2015 State representation is fundamental to behavior. However, identifying the true state of the world is challenging when explicit cues are ambiguous. Here, Bradfield and colleagues show that the medial OFC is critical for using associative information to discriminate ambiguous states.
Sharpe, Melissa J. +3 more
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The Orbitofrontal Cortex in Temporal Cognition [PDF]
Behavioral Neuroscience, 2020 Abstract One of the most important factors in decision making is estimating the value of available options. Subregions of the prefrontal cortex, including the orbitofrontal cortex (OFC), have been deemed essential for this process. Value computations require a complex integration across numerous dimensions, including, reward magnitude ...
Juan Luis Romero Sosa +2 more
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The magical orbitofrontal cortex. [PDF]
Behavioral Neuroscience, 2021 This special issue, commissioned after the 4th Quadrennial Meeting on Orbitofrontal Cortex Function held in Paris in November of 2019 (https://ofc2019.sciencesconf.org/), is intended to provide a snapshot of this ongoing transformation; we hope that the ideas presented herein will provide a foundation for the next stage in the evolution of our ...
Schoenbaum, Geoffrey +4 more
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Encoding touch and the orbitofrontal cortex [PDF]
Human Brain Mapping, 2009 AbstractLesion studies on nonhuman primates utilizing recognition memory tests have shown that the orbitofrontal cortex is critical for the encoding of novel information, and anatomical studies have shown that the orbitofrontal cortex forms part of a mnemonic circuit that connects limbic medial temporal areas with higher‐order lateral frontal cortical ...
Stephen, Frey +2 more
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The orbitofrontal cortex and response selection [PDF]
Annals of the New York Academy of Sciences, 2011 Orbitofrontal cortex (OFC) function is often characterized in terms of stimulus–reward mapping; however, more recent evidence suggests that the OFC may play a role in selecting and representing extended actions. First, previously encoded reward associations in the OFC could be used to inform responding in novel but similar situations.
James J, Young, Matthew L, Shapiro
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Orbitofrontal Cortex and Memory Formation [PDF]
Neuron, 2002 Which one of the many regions of the anatomically heterogeneous prefrontal cortex is part of the critical core of the neural circuit for encoding? This positron emission tomography (PET) experiment measured changes in cerebral blood flow (CBF) in normal human participants during the presentation of abstract visual information in four conditions that ...
Frey, Stephen, Petrides, Michael
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The stressed orbitofrontal cortex.
Behavioral Neuroscience, 2021 Stressor exposure causes dendritic remodeling on excitatory neurons in multiple regions of the brain, including the orbitofrontal cortex (OFC). Additionally, stressor and exogenous stress hormone exposure impair cognitive functions that are dependent on the OFC.
Michelle K. Sequeira, Shannon L. Gourley
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Medial-lateral Organization of the Orbitofrontal Cortex [PDF]
Journal of Cognitive Neuroscience, 2014 Abstract Emerging evidence suggests that specific cognitive functions localize to different subregions of OFC, but the nature of these functional distinctions remains unclear. One prominent theory, derived from human neuroimaging, proposes that different stimulus valences are processed in separate orbital regions, with medial and lateral
Erin L. Rich, Jonathan D. Wallis
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Frontiers in Behavioral Neuroscience, 2015 This study investigated the role of bottom-up and top-down neural mechanisms in the processing of emotional face expression during memory formation. Functional brain imaging data was acquired during incidental learning of positive (‘happy’), neutral and ...
Daiming eXiu +5 more
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