Results 11 to 20 of about 393,980 (293)
The magical orbitofrontal cortex. [PDF]
Behavioral Neuroscience, 2021 This special issue, commissioned after the 4th Quadrennial Meeting on Orbitofrontal Cortex Function held in Paris in November of 2019 (https://ofc2019.sciencesconf.org/), is intended to provide a snapshot of this ongoing transformation; we hope that the ideas presented herein will provide a foundation for the next stage in the evolution of our ...
Schoenbaum, Geoffrey +4 more
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Orbitofrontal Cortex and Memory Formation [PDF]
Neuron, 2002 Which one of the many regions of the anatomically heterogeneous prefrontal cortex is part of the critical core of the neural circuit for encoding? This positron emission tomography (PET) experiment measured changes in cerebral blood flow (CBF) in normal human participants during the presentation of abstract visual information in four conditions that ...
Frey, Stephen, Petrides, Michael
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Encoding touch and the orbitofrontal cortex [PDF]
Human Brain Mapping, 2009 AbstractLesion studies on nonhuman primates utilizing recognition memory tests have shown that the orbitofrontal cortex is critical for the encoding of novel information, and anatomical studies have shown that the orbitofrontal cortex forms part of a mnemonic circuit that connects limbic medial temporal areas with higher‐order lateral frontal cortical ...
Stephen, Frey +2 more
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Orbitofrontal Cortex Assigns Credit Wisely [PDF]
Neuron, 2010 Damage in the orbitofrontal cortex impairs the ability to switch behaviors when their outcomes change, but the cause of these deficits remained unknown. In this issue of Neuron, Walton et al. demonstrate a key role of the primate orbitofrontal cortex in disambiguating the relationship between multiple choices and their outcomes.
Seo, Hyojung, Lee, Daeyeol
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Attention-dependent modulation of cortical taste circuits revealed by Granger causality with signal-dependent noise. [PDF]
PLoS Computational Biology, 2013 We show, for the first time, that in cortical areas, for example the insular, orbitofrontal, and lateral prefrontal cortex, there is signal-dependent noise in the fMRI blood-oxygen level dependent (BOLD) time series, with the variance of the noise ...
Qiang Luo +4 more
doaj +2 more sources
Orbitofrontal cortex abnormalities in schizophrenia
Epidemiologia e Psichiatria Sociale, 2010 AbstractThe magnetic resonance imaging studies investigating the volumes of the orbitofrontal cortex in patients suffering from schizophrenia are here presented, trying to elucidate its role for the pathophysiology and for the cognition of the disease.
Bellani, M, Cerruti, S, Brambilla, P
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Targeting the KCNC3-Dependent Anterior Insular-Lateral Orbitofrontal Cortex Glutamatergic Circuit Attenuates Post-Traumatic Anxiety. [PDF]
Adv Sci (Weinh)Frontal lobe traumatic brain injury is associated with hyperactivity of an insular–orbitofrontal circuit in both patients and mice. By combination of integrating functional imaging, cell‐type–specific circuit manipulation, single‐cell transcriptomics, and whole‐cell recordings, this work identifies the downregulation of the potassium channel KCNC3 in ...
Li MG +10 more
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On the orbitofrontal cortex and encoding
, 2003 This item was digitized as part of a project to share McGill's intellectual legacy with the public. If you are the copyright holder or a relative of the copyright holder who is deceased, you may request withdrawal by emailing escholarship.library@mcgill.ca.
Frey, Stephen
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Current Biology, 2018 The orbitofrontal cortex is a large and heterogeneous cortical area on the ventral surface of the frontal lobe and is intimately involved in emotion and executive function. In this Primer, Peter Rudebeck and Erin Rich summarize our understanding of the mechanisms through which orbitofrontal cortex adaptively shapes decision making and affective ...
Peter H, Rudebeck, Erin L, Rich
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The State of the Orbitofrontal Cortex [PDF]
Neuron, 2015 State representation is fundamental to behavior. However, identifying the true state of the world is challenging when explicit cues are ambiguous. Here, Bradfield and colleagues show that the medial OFC is critical for using associative information to discriminate ambiguous states.
Sharpe, Melissa J. +3 more
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