Results 41 to 50 of about 46,771 (232)

Advancement of PD Is Reflected by White Matter Changes in Olfactory Areas: A Pilot Study

Medicina, 2021
Loss of sense of smell is a well-known non-motor symptom of Parkinson’s disease (PD). Here, we present insight into the association between PD advancement and equivalents of smell loss in olfactory-eloquent brain areas, such as the posterior cortex and ...
Thomas Hummel, Antje Haehner, Divesh Thaploo, Charalampos Georgiopoulos, Björn Falkenburger, Katherine Whitcroft   +5 more
doaj   +1 more source

Volumetric alterations of the orbitofrontal cortex in autism [PDF]

Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2007
Recent evidence has implicated the orbitofrontal cortex (OFC) in the pathophysiology of social deficits in autism. An MRI-based morphometric study of the OFC was conducted involving 11 children with autism (age range 8.1-12.7 years) and 18 healthy, age-matched controls (age range 8.9-12.8 years). Decreased grey matter volume in the right lateral OFC in
Ragy R, Girgis, Nancy J, Minshew, Nadine M, Melhem, Jeffrey J, Nutche, Matcheri S, Keshavan, Antonio Y, Hardan   +5 more
openaire   +2 more sources

Orbitofrontal Cortex Assigns Credit Wisely [PDF]

Neuron, 2010
Damage in the orbitofrontal cortex impairs the ability to switch behaviors when their outcomes change, but the cause of these deficits remained unknown. In this issue of Neuron, Walton et al. demonstrate a key role of the primate orbitofrontal cortex in disambiguating the relationship between multiple choices and their outcomes.
Seo, Hyojung, Lee, Daeyeol
openaire   +2 more sources

Neuroscience: Reevaluating the Role of Orbitofrontal Cortex [PDF]

Current Biology, 2019
A new optogenetic lesion study shows that the orbitofrontal cortex is essential for integrating information about recent rewards - which may either increase or decrease demand for more - with learned preferences to drive behavior.
Brianna J, Sleezer, Benjamin Yost, Hayden   +1 more
openaire   +2 more sources

FDG‐PET Associations With Disease Severity and Outcomes in NMDA‐Receptor IgG Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Patients with N‐methyl‐D‐aspartate (NMDA) receptor‐immunoglobulin G (IgG) autoimmune encephalitis (NMDAR‐IgG AE) demonstrate occipital lobe hypometabolism on baseline brain fluorodeoxyglucose‐positron emission tomography (bFDG‐PET).
Jonathan K. Lee, Jeffrey Lambe, Scott Johnson, Akua Abrah, Jennifer Bullen, Jeffrey A. Cohen, Tatchaporn Ongphichetmetha, Amy Kunchok   +7 more
wiley   +1 more source

Serial pathways from primate prefrontal cortex to autonomic areas may influence emotional expression

BMC Neuroscience, 2003
Background Experiencing emotions engages high-order orbitofrontal and medial prefrontal areas, and expressing emotions involves low-level autonomic structures and peripheral organs. How is information from the cortex transmitted to the periphery? We used
Saha Subhash, Barbas Helen, Rempel-Clower Nancy, Ghashghaei Troy   +3 more
doaj   +1 more source

Orbitofrontal Cortex and Neuromaturation: A Gateway to Risk? [PDF]

Biological Psychiatry, 2012
Adolescence is a period of intense vulnerability to drug use initiation and adolescents may be more susceptible than adults to becoming drug dependent (1). Cannabis use initiation during adolescence has emerged as a significant concern, as early initiation of cannabis use has been associated with increased risk for using a range of other drugs of abuse
John C, Churchwell, Melissa, Lopez-Larson, Deborah A, Yurgelun-Todd   +2 more
openaire   +2 more sources

Multiscale Coupling From Mastication to Retronasal Aroma Perception: The PG‐DTCFN Model and Multiphysics Simulation

Advanced Science, EarlyView.
Using grilled lamb skewers as a model system, this work builds a multiscale coupling framework from oral processing to retronasal aroma perception, reveals dual‐kinetic release patterns and Electroencephalogram‐characterized central encoding features, and proposes an interpretable physics‐guided deep learning model validated by multiphysics simulation,
Che Shen, Xiongfeng He, Zihao Li, Zidong Chen, Jiajin Sun, Xinyu Jiang, Yunhui Zhang, Lizhang Wu, Ran Wang, Jingnan Lu, Bo Wang, Kezhou Cai, Baocai Xu   +12 more
wiley   +1 more source

Targeting the KCNC3‐Dependent Anterior Insular‐Lateral Orbitofrontal Cortex Glutamatergic Circuit Attenuates Post‐Traumatic Anxiety

Advanced Science, EarlyView.
Frontal lobe traumatic brain injury is associated with hyperactivity of an insular–orbitofrontal circuit in both patients and mice. By combination of integrating functional imaging, cell‐type–specific circuit manipulation, single‐cell transcriptomics, and whole‐cell recordings, this work identifies the downregulation of the potassium channel KCNC3 in ...
Meng‐Ge Li, Xiao‐Bo Qian, Hai‐Long Zhang, Di Li, Ling Ji, Xin‐Chun Xu, Jia‐Sheng Ding, Li‐Jun Yin, Li Zhang, Guang‐Yin Xu, Rong Gao   +10 more
wiley   +1 more source

Differences in Brain Activity and Body Movements Between Virtual Reality and Offline Exercise: Randomized Crossover Trial

JMIR Serious Games, 2023
BackgroundVirtual reality (VR) has been suggested to be effective at enhancing physical exercises because of its immersive characteristics.
Hee Jin Kim, Jea Woog Lee, Gangta Choi, Junghoon Huh, Doug Hyun Han   +4 more
doaj   +1 more source