Poor performance on the Iowa gambling task in children with obsessive-compulsive disorder
Annals of General Psychiatry, 2012 Background Several lines of evidence implicate orbitofrontal cortex dysfunction in the pathophysiology of obsessive-compulsive disorder (OCD). The purpose of this study was to investigate neuropsychological dysfunction of the orbitofrontal cortex in ...
Kodaira Masaki +9 more
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Altered structural and effective connectivity in anorexia and bulimia nervosa in circuits that regulate energy and reward homeostasis. [PDF]
, 2016 Anorexia and bulimia nervosa are severe eating disorders that share many behaviors. Structural and functional brain circuits could provide biological links that those disorders have in common.
Frank, GKW +3 more
core +1 more source
Decreased brain connectivity in smoking contrasts with increased connectivity in drinking
eLife, 2019 In a group of 831 participants from the general population in the Human Connectome Project, smokers exhibited low overall functional connectivity, and more specifically of the lateral orbitofrontal cortex which is associated with non-reward mechanisms ...
Wei Cheng +16 more
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Striatum-Centered Fiber Connectivity Is Associated with the Personality Trait of Cooperativeness. [PDF]
PLoS ONE, 2016 Cooperativeness is an essential behavioral trait evolved to facilitate group living. Social and cognitive mechanisms involved in cooperation (e.g., motivation, reward encoding, action evaluation, and executive functions) are sub-served by the striatal ...
Xuemei Lei +6 more
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Dissociating the Role of the Orbitofrontal Cortex and the Striatum in the Computation of Goal Values and Prediction Errors [PDF]
, 2008 To make sound economic decisions, the brain needs to compute several different value-related signals. These include goal values that measure the predicted reward that results from the outcome generated by each of the actions under consideration, decision
Camerer, Colin F. +4 more
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NeuroImage, 2020 Sensation-seeking is a multifaceted personality trait with components that include experience-seeking, thrill and adventure seeking, disinhibition, and susceptibility to boredom, and is an aspect of impulsiveness.
Zhuo Wan, MSc +3 more
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Aversive event anticipation affects connectivity between the ventral striatum and the orbitofrontal cortex in an fMRI avoidance task. [PDF]
PLoS ONE, 2013 Ability to anticipate aversive events is important for avoiding dangerous or unpleasant situations. The motivation to avoid an event is influenced by the incentive salience of an event-predicting cue. In an avoidance fMRI task we used tone intensities to
Ingeborg Bolstad +5 more
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Which Way Was I Going? Contextual Retrieval Supports the Disambiguation of Well Learned Overlapping Navigational Routes [PDF]
, 2010 Groundbreaking research in animals has demonstrated that the hippocampus contains neurons that distinguish betweenoverlapping navigational trajectories.
Brown, Thackery I +4 more
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Orbitofrontal epilepsy: Electroclinical analysis of surgical cases and literature review [PDF]
, 2004 Clinical and electrographic data were reviewed on 2 of our patients with orbitofrontal epilepsy who were seizure free at 5-year follow-up, and on 2 similar patients from the literature.
King, Don W. +4 more
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The Orbitofrontal Cortex and Reward [PDF]
Cerebral Cortex, 2000 The primate orbitofrontal cortex contains the secondary taste cortex, in which the reward value of taste is represented. It also contains the secondary and tertiary olfactory cortical areas, in which information about the identity and also about the reward value of odors is represented. The orbitofrontal cortex also receives information about the sight
openaire +2 more sources