Results 31 to 40 of about 393,980 (293)

Poor performance on the Iowa gambling task in children with obsessive-compulsive disorder

Annals of General Psychiatry, 2012
Background Several lines of evidence implicate orbitofrontal cortex dysfunction in the pathophysiology of obsessive-compulsive disorder (OCD). The purpose of this study was to investigate neuropsychological dysfunction of the orbitofrontal cortex in ...
Kodaira Masaki, Iwadare Yoshitaka, Ushijima Hirokage, Oiji Arata, Kato Motoichiro, Sugiyama Nobuhiro, Sasayama Daimei, Usami Masahide, Watanabe Kyota, Saito Kazuhiko   +9 more
doaj   +1 more source

Decreased brain connectivity in smoking contrasts with increased connectivity in drinking

eLife, 2019
In a group of 831 participants from the general population in the Human Connectome Project, smokers exhibited low overall functional connectivity, and more specifically of the lateral orbitofrontal cortex which is associated with non-reward mechanisms ...
Wei Cheng, Edmund T Rolls, Trevor W Robbins, Weikang Gong, Zhaowen Liu, Wujun Lv, Jingnan Du, Hongkai Wen, Liang Ma, Erin Burke Quinlan, Hugh Garavan, Eric Artiges, Dimitri Papadopoulos Orfanos, Michael N Smolka, Gunter Schumann, Keith Kendrick, Jianfeng Feng   +16 more
doaj   +1 more source

Striatum-Centered Fiber Connectivity Is Associated with the Personality Trait of Cooperativeness. [PDF]

PLoS ONE, 2016
Cooperativeness is an essential behavioral trait evolved to facilitate group living. Social and cognitive mechanisms involved in cooperation (e.g., motivation, reward encoding, action evaluation, and executive functions) are sub-served by the striatal ...
Xuemei Lei, Chuansheng Chen, Chunhui Chen, Qinghua He, Robert K Moyzis, Gui Xue, Qi Dong   +6 more
doaj   +1 more source

How the brain represents the reward value of fat in the mouth. [PDF]

, 2009
The palatability and pleasantness of the sensory properties of foods drive food selection and intake and may contribute to overeating and obesity. Oral fat texture can make food palatable and pleasant.
Parris, Benjamin, De Souza, Arun, Rolls, Edmund T., Grabenhorst, Fabian   +3 more
core   +1 more source

Aversive event anticipation affects connectivity between the ventral striatum and the orbitofrontal cortex in an fMRI avoidance task. [PDF]

PLoS ONE, 2013
Ability to anticipate aversive events is important for avoiding dangerous or unpleasant situations. The motivation to avoid an event is influenced by the incentive salience of an event-predicting cue. In an avoidance fMRI task we used tone intensities to
Ingeborg Bolstad, Ole A Andreassen, Greg E Reckless, Niels P Sigvartsen, Andres Server, Jimmy Jensen   +5 more
doaj   +1 more source

Aberrant NF-kappaB expression in autism spectrum condition : a mechanism for neuroinflammation [PDF]

, 2011
Autism spectrum condition (ASC) is recognized as having an inflammatory component. Post-mortem brain samples from patients with ASC display neuroglial activation and inflammatory markers in cerebrospinal fluid, although little is known about the ...
Young, Adam, Suckling, John, Sarah Lynch, Campbell, Elaine Catherine, Lynch, Sarah Janice, Elaine eCampbell, Powis, Simon J, Simon J. Powis, Adam eYoung, Sarah eLynch, Simon ePowis, Lynch, Sarah, Adam M. H. Young, Elaine Campbell, John Suckling, John eSuckling, Young, Adam M H, Powis, Simon John, Campbell, Elaine   +18 more
core   +2 more sources

Sensation-seeking is related to functional connectivities of the medial orbitofrontal cortex with the anterior cingulate cortex

NeuroImage, 2020
Sensation-seeking is a multifaceted personality trait with components that include experience-seeking, thrill and adventure seeking, disinhibition, and susceptibility to boredom, and is an aspect of impulsiveness.
Zhuo Wan, MSc, Edmund T. Rolls, DSc, Wei Cheng, PhD, Jianfeng Feng, PhD   +3 more
doaj   +1 more source

Olfactory Loss and Brain Connectivity after COVID-19: Structural Follow-Up at One Year

Neural Plasticity, 2023
The structural connectivity from the primary olfactory cortex to the main secondary olfactory areas was previously reported as relatively increased in the medial orbitofrontal cortex in a cohort of 27 recently SARS-CoV-2-infected (COV+) subjects, of ...
Fabrizio Esposito, Mario Cirillo, Rosa De Micco, Giuseppina Caiazzo, Mattia Siciliano, Andrea G. Russo, Caterina Monari, Nicola Coppola, Gioacchino Tedeschi, Alessandro Tessitore   +9 more
doaj   +1 more source

Assessment of olfactory information in the human brain using 7-Tesla functional magnetic resonance imaging

NeuroImage, 2021
Olfaction could prove to be an early marker of neurodegenerative diseases, including Alzheimer's and Parkinson's diseases. To use olfaction for disease diagnosis, elucidating the standard olfactory functions in healthy humans is necessary.
Yuka Donoshita, Uk-Su Choi, Hiroshi Ban, Ikuhiro Kida   +3 more
doaj   +1 more source

Model-Based Decision Making in the Human Brain [PDF]

, 2007
Many real-life decision making problems incorporate higher-order structure, involving interdependencies between different stimuli, actions, and subsequent rewards.
Hampton, Alan Nicolás
core   +1 more source