Results 61 to 70 of about 3,669 (198)

Structural studies of orbivirus particles

, 1998
We are using crystallographic methods to investigate the structure of AHSV and BTV. Our initial approach was to investigate the structure of the major protein component of the viral core, VP7(T13). This trimeric protein has been studied in several crystal forms from both orbiviruses and reveals a structure made up of conserved domains, capable of ...
Stuart, Di, Gouet, P., Grimes, J., Malby, R., Diprose, J., Zientara, Stéphan, Burroughs, Jn, Mertens, Pp   +7 more
openaire   +5 more sources

Endemic and Emerging Arboviruses in Domestic Ruminants in East Asia

Frontiers in Veterinary Science, 2020
Epizootic congenital abnormalities caused by Akabane, Aino, and Chuzan viruses have damaged the reproduction of domestic ruminants in East Asia for many years.
Tohru Yanase, Katsunori Murota, Yoko Hayama   +2 more
doaj   +1 more source

The Absence of Abdominal Pigmentation in Livestock Associated Culicoides following Artificial Blood Feeding and the Epidemiological Implication for Arbovirus Surveillance

Pathogens, 2021
Culicoides midges (Diptera: Ceratopogonidae), the vectors of economically important arboviruses such as bluetongue virus and African horse sickness virus, are of global importance.
Maria Goffredo, Michela Quaglia, Matteo De Ascentis, Silvio Gerardo d’Alessio, Valentina Federici, Annamaria Conte, Gert Johannes Venter   +6 more
doaj   +1 more source

Development and evaluation of recombinase polymerase amplification combined with lateral flow dipstick assays for co-detection of epizootic haemorrhagic disease virus and the Palyam serogroup virus

BMC Veterinary Research, 2021
Background Epizootic haemorrhagic disease virus (EHDV) and the Palyam serogroup viruses (PALV) have led to significant economic losses associated with livestock production globally.
Zhuo-ran Li, Zhen-xing Yang, Zhan-hong Li, Xiang Gao, Zhong-yan Hu, Heng Yang, De-fang Liao   +6 more
doaj   +1 more source

Nanoparticle- and Microparticle-Based Vaccines against Orbiviruses of Veterinary Importance

Vaccines, 2022
Bluetongue virus (BTV) and African horse sickness virus (AHSV) are widespread arboviruses that cause important economic losses in the livestock and equine industries, respectively.
Luis Jiménez-Cabello, Sergio Utrilla-Trigo, Natalia Barreiro-Piñeiro, Tomás Pose-Boirazian, José Martínez-Costas, Alejandro Marín-López, Javier Ortego   +6 more
doaj   +1 more source

Specific T-cell subsets have a role in anti-viral immunity and pathogenesis but not viral dynamics or onwards vector transmission of an important livestock arbovirus

Frontiers in Immunology
IntroductionBluetongue virus (BTV) is an arthropod-borne Orbivirus that is almost solely transmitted by Culicoides biting midges and causes a globally important haemorrhagic disease, bluetongue (BT), in susceptible ruminants.
Kerry Newbrook, Nakibul Khan, Nakibul Khan, Aimee Fisher, Aimee Fisher, Karen Chong, Karen Chong, Simon Gubbins, William C. Davies, Christopher Sanders, Marc Guimerà Busquets, Lyndsay Cooke, Amanda Corla, Martin Ashby, John Flannery, Carrie Batten, Jessica E. Stokes, Beatriz Sanz-Bernardo, Simon Carpenter, Katy Moffat, Karin E. Darpel, Karin E. Darpel, Karin E. Darpel   +22 more
doaj   +1 more source

Isolation and Phylogenetic Grouping of Equine Encephalosis Virus in Israel

Emerging Infectious Diseases, 2011
During 2008–2009 in Israel, equine encephalosis virus (EEV) caused febrile outbreaks in horses. Phylogenetic analysis of segment 10 of the virus strains showed that they form a new cluster; analysis of segment 2 showed ≈92% sequence identity to EEV-3 ...
Karin Aharonson-Raz, Amir Steinman, Velizar Bumbarov, Sushila Maan, Narender Singh Maan, Kyriaki Nomikou, Carrie Batten, Christiaan Potgieter, Yuval Gottlieb, Peter Mertens, Eyal Klement   +10 more
doaj   +1 more source

Structural Studies on Orbivirus Proteins and Particles

, 2006
X-ray and electron microscopy analysis of Bluetongue virus (BTV), the type species of the Orbivirus genus within the family Reoviridae, have revealed various aspects of the organisation and structure of the proteins that form the viral capsid. Orbiviruses have a segmented dsRNA genome, which imposes constraints on their structure and life cycle.
Stuart, D, Grimes, J
openaire   +4 more sources

Characterization of a Novel Reassortant Epizootic Hemorrhagic Disease Virus Serotype 6 Strain Isolated from Diseased White-Tailed Deer (Odocoileus virginianus) on a Florida Farm

Viruses, 2022
We report an outbreak of a novel reassortant epizootic hemorrhagic disease virus serotype 6 (EHDV-6) in white-tailed deer (WTD) on a Florida farm in 2019.
Thaís C. S. Rodrigues, Pedro H. O. Viadanna, Kuttichantran Subramaniam, Ian K. Hawkins, Albert B. Jeon, Julia C. Loeb, Juan M. C. Krauer, John A. Lednicky, Samantha M. Wisely, Thomas B. Waltzek   +9 more
doaj   +1 more source

Structures of orbivirus VP7: implications for the role of this protein in the viral life cycle [PDF]

Structure, 1997
Bluetongue virus (BTV) is the prototypical virus of the genus orbivirus in the family Reoviridae and causes an economically important disease in domesticated animals, such as sheep. BTV is larger and more complex than any virus for which comprehensive atomic level structural information is available.
Basak, A, Grimes, J, Gouet, P, Roy, P, Stuart, D   +4 more
openaire   +3 more sources