Results 111 to 120 of about 59,800 (265)
Advanced Science, EarlyView.FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni +17 more
wiley +1 more source
Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae
Advanced Science, EarlyView.Integrated artificial intelligence (AI) ensembles identify highly potent repurposed drugs against Streptococcus pneumoniae. Prospective virtual screening of 6747 drugs uncovers nine active candidates, including thiostrepton. This drug exhibits low picomolar potency and bypasses established resistance in multidrug‐resistant strains, demonstrating an ...
Joshua S. Fitch +6 more
wiley +1 more source
Geometry‐Encoded Actuation as a Structural Interaction Layer in Origami Robots
Advanced Science, EarlyView.We present geometry‐encoded actuation (GEA), a design framework that integrates multistable origami with liquid crystal elastomer actuators to encode environmental interactions into autonomous structural responses. GEA enables programmable shape transformation without continuous sensing or complex control, achieving robust adaptive manipulation and ...
Jianshu Zhou +8 more
wiley +1 more source
F‐Type Pyocin Versus Phage λ Tail: Conserved Hub, Divergent Fibers
Advanced Science, EarlyView.Near‐atomic cryo‐EM structures of a Gram‐negative F‐type pyocin reveal a conserved tail tip architecture shared with bacteriophage λ together with a previously unrecognized side‐fiber attachment mode. These findings provide new insight into tailocin assembly and host recognition and establish a structural framework for engineering precision ...
Zhiwei Gu +5 more
wiley +1 more source
Dipolar Coupling Errors in Nuclear Spin Qubits
Advanced Science, EarlyView.Multi‐nuclear spin registers of phosphorus‐atom qubits in silicon have demonstrated 99.99% single and >$>$99.9% two qubit gate fidelities. Despite nanometer separation, read‐out fidelities between individual nuclear spins within the register are not identical.
I. D. Thorvaldson +15 more
wiley +1 more source
Order-picking systems and methods
, 2006 The order-picking process is the most laborious and the most costly activity in a typical warehouse. As 50% of total order picking time is spent on traveling, organizational changes and application of various order-picking methods to reduce travel distances could lead to significant improvements. In this paper routing, storage and orderbatching methods
Oluić, Čedomir, Đukić, Goran
openaire +1 more source
Advanced Science, EarlyView.This work presents a computational–experimental strategy to engineer material‐binding peptides toward polymer specificity. Molecular dynamics simulations identified residues driving polystyrene binding, enabling targeted substitutions that greatly reduced polystyrene affinity while preserving PET binding.
Julian Luka +3 more
wiley +1 more source
Predicting Emotion and Engagement of Workers in Order Picking Based on Behavior and Pulse Waves Acquired by Wearable Devices. [PDF]
Sensors (Basel), 2019 Kajiwara Y, Shimauchi T, Kimura H.
europepmc +1 more source
Canonical Antibodies Adopt Distinct Binding Modes to Recognize Viral Glycan Shields
Advanced Science, EarlyView.Canonical Y‐shaped antibodies recognize viral glycan shields through adaptive Fab assembly states shaped by glycan organization and somatic hypermutation. Structural analyses ofbroadly neutralizing antibodies VRC35 and VRC36 across glycoproteins of HIV‐1, influenza, SARS‐CoV‐2, and Lassa viruses reveal distinct Fab assembly states, spanning monovalent,
Jiaxuan Cheng +71 more
wiley +1 more source
The Impact of Visual Guided Order Picking on Ocular Comfort, Ocular Surface and Tear Function. [PDF]
PLoS One, 2016 Klein-Theyer A +7 more
europepmc +1 more source