Results 91 to 100 of about 619,936 (293)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

open access: yesFEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile   +8 more
wiley   +1 more source

Security Analysis of Order Preserving Symmetric Cryptography”, [PDF]

open access: yes, 2013
: Order preserving encryption is a type of homomorphic encryption in which the homomorphic operation is order comparison. This means that comparing encrypted data returns the same result than comparing the original data.
Magda Valls   +7 more
core  

A lightweight privacy-preserving truth discovery mechanism for IoT

open access: yesDianxin kexue, 2021
In order to solve diverse quality and privacy leakage of perceived data in fog-cloud integrated internet of things (IoT), a streaming encryption-based privacy-preserving truth discovery mechanism for IoT was proposed.Firstly, by utilizing shuffling and ...
Yingjie HE   +5 more
doaj   +2 more sources

Part 1 of Martin’s Conjecture for order-preserving and measure-preserving functions

open access: yesJournal of the American Mathematical Society
Martin’s Conjecture is a proposed classification of the definable functions on the Turing degrees. It is usually divided into two parts, the first of which classifies functions which are not above the identity and the second of which classifies functions which are above the identity.
Lutz, Patrick, Siskind, Benjamin
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

On better approximation order for the max-product Meyer-König and Zeller operator

open access: yesDemonstratio Mathematica
Bede et al. (B. Bede, L. Coroianu, and S. G. Gal, Approximation and shape preserving properties of the nonlinear Meyer-König and Zeller operator of max-product kind, Numer. Funct. Anal. Optim. 31 (2010), no.
Çit Sezin, Doğru Ogün
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Robust detail-preserving signal extraction [PDF]

open access: yes
We discuss robust filtering procedures for signal extraction from noisy time series. Particular attention is paid to the preservation of relevant signal details like abrupt shifts. moving averages and running medians are widely used but have shortcomings
Fried, Roland   +2 more
core  

Optimal extensions for positive order continuous operators on Banach functions spaces [PDF]

open access: yes, 2014
In this paper we give conditions under which a positive order continuous operator T defined on a Banach function space can be extended, preserving the order continuity in a certain optimal way.
Delgado Garrido, Olvido
core   +1 more source

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