Results 41 to 50 of about 173,725,199 (293)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
A two - grid, fourth order method for nonlinear fourth order boundary value problems [PDF]
, 1985 A fourth order convergent finite difference method is developed for the numerical solution of the nonlinear fourth order boundary value problem y(iv)(x) = f(x,y ...
Twizell, E H
core +4 more sources
Comparison of two types of order convergence with topological convergence in an ordered topological vector space [PDF]
Proceedings of the American Mathematical Society, 1977 Birkhoff and Peressini proved that if ( X , T
May, Roger W., McArthur, Charles W.
openaire +2 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
On Multivariate Bernstein Polynomials
Mathematics, 2020 In this paper, we first revisit and bring together as a sort of survey, properties of Bernstein polynomials of one variable. Secondly, we extend the results from one variable to several ones, namely—uniform convergence, uniform convergence of the ...
Mama Foupouagnigni +1 more
doaj +1 more source
The second order spectrum and optimal convergence [PDF]
Mathematics of Computation, 2013 The method of second order relative spectra has been shown to reliably approximate the discrete spectrum for a self-adjoint operator. We extend the method to normal operators and find optimal convergence rates for eigenvalues and eigenspaces. The convergence to eigenspaces is new, while the convergence rate for eigenvalues improves on the previous ...
openaire +4 more sources
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Complete convergence for arrays of minimal order statistics
International Journal of Mathematics and Mathematical Sciences, 2004 For arrays of independent Pareto random variables, this paper establishes complete convergence for weighted partial sums for the smaller order statistics within each row. This result improves on past strong laws.
André Adler
doaj +1 more source