Results 51 to 60 of about 333,767 (302)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The second order spectrum and optimal convergence [PDF]
Mathematics of Computation, 2013 The method of second order relative spectra has been shown to reliably approximate the discrete spectrum for a self-adjoint operator. We extend the method to normal operators and find optimal convergence rates for eigenvalues and eigenspaces. The convergence to eigenspaces is new, while the convergence rate for eigenvalues improves on the previous ...
openaire +4 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Second order predictor-corrector pairs [PDF]
, 1976 The purpose of this study is to introduce multistep methods for approximating the solutions of ordinary differential equations and to study the general convergent, second order, predictor-corrector pair.
Franklin, Carol Marley +1 more
core
FEBS Letters, EarlyView.The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile +8 more
wiley +1 more source
Expanding the convergence domain for chun-stanica-neta family of third order methods in banach spaces [PDF]
, 2015 We present a semilocal convergence analysis of a third order method for approximating a locally unique solution of an equation in a Banach space setting. Recently, this method was studied by Chun, Stanica and Neta.
George, Santhosh +2 more
core +1 more source
Complete convergence for arrays of minimal order statistics
International Journal of Mathematics and Mathematical Sciences, 2004 For arrays of independent Pareto random variables, this paper establishes complete convergence for weighted partial sums for the smaller order statistics within each row. This result improves on past strong laws.
André Adler
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
A two - grid, fourth order method for nonlinear fourth order boundary value problems [PDF]
, 1985 A fourth order convergent finite difference method is developed for the numerical solution of the nonlinear fourth order boundary value problem y(iv)(x) = f(x,y ...
Twizell, E H
core
Generalized convergence analysis of the fractional order systems
Open Physics, 2018 The aim of the present work is to generalize the contraction theory for the analysis of the convergence of fractional order systems for both continuous-time and discrete-time systems.
Ruzitalab Ahmad +2 more
doaj +1 more source