Results 71 to 80 of about 5,038,205 (326)

Characterizations of Pareto, Weibull and Power Function Distributions Based On Generalized Order Statistics [PDF]

open access: yes, 2016
Characterizations of probability distributions by different regression conditions on generalized order statistics has attracted the attention of many researchers.
Ahsanullah, M., Hamedani, Gholamhossein
core   +1 more source

Two-sided estimates for order statistics of log-concave random vectors

open access: yes, 2019
We establish two-sided bounds for expectations of order statistics ($k$-th maxima) of moduli of coordinates of centered log-concave random vectors with uncorrelated coordinates.
C Borell   +11 more
core   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Complete convergence for arrays of ratios of order statistics

open access: yesOpen Mathematics, 2019
Let {Xn,k, 1 ≤ k ≤ mn, n ≥ 1} be an array of independent random variables from the Pareto distribution. Let Xn(k) be the kth largest order statistic from the nth row of the array and set Rn,in,jn = Xn(jn)/Xn(in) where jn < in. The aim of this paper is to
Miao Yu   +3 more
doaj   +1 more source

Some Results on a Generalized Residual Entropy based on Order Statistics

open access: yesStatistica, 2014
In the present paper, we discuss some monotone properties of the GRE of order (α, β) in order statistics under various assumptions. It is shown that monotone properties are preserved under the formation of a parallel system but not under the formation of
Suchandan Kayal
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Exact distributions of order statistics from ln,p-symmetric sample distributions

open access: yesDependence Modeling, 2017
We derive the exact distributions of order statistics from a finite number of, in general, dependent random variables following a joint ln,p-symmetric distribution. To this end,we first review the special cases of order statistics fromspherical aswell as
Müller K., Richter W.-D.
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Using Order Texture Statistics to Classify Multi-Class Malware

open access: yesScientific Journal of King Faisal University: Basic and Applied Sciences
The most significant challenge in the security of information and communication networks is the escalating number of malware types, followed by the search for appropriate methods to protect systems against them, which is one of the most critical concerns
Raaed Fadhil Mohammed
doaj   +1 more source

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