Results 61 to 70 of about 1,373,001 (268)

Hierarchical orderings of textual units [PDF]

Proceedings of the 19th international conference on Computational linguistics -, 2002
Text representation is a central task for any approach to automatic learning from texts. It requires a format which allows to interrelate texts even if they do not share content words, but deal with similar topics. Furthermore, measuring text similarities raises the question of how to organize the resulting clusters. This paper presents cohesion trees (
openaire   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Prognostic factors for advanced lung cancer patients with do-not-intubate order in intensive care unit: a retrospective study

BMC Pulmonary Medicine, 2022
Background The survival of patients with lung cancer undergoing critical care has improved. An increasing number of patients with lung cancer have signed a predefined do-not-intubate (DNI) order before admission to the intensive care unit (ICU).
Chia-I Shen, Shan-Yao Yang, Hwa-Yen Chiu, Wei-Chih Chen, Wen-Kuang Yu, Kuang-Yao Yang   +5 more
doaj   +1 more source

Positive Derivations on Partially Ordered Linear Algebra With an Order Unit [PDF]

Proceedings of the American Mathematical Society, 1978
We show that the range of a positive derivation on a Dedekind σ \sigma -complete partially ordered linear algebra with an order unit is a set of generalized nilpotents. With additional assumptions on the algebra, we show that the algebra has an important property similar to a property of the algebra of upper triangular matrices.
Dai, Taen-Yu, DeMarr, Ralph
openaire   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Modified Current Differencing Unit and its Application for Electronically Reconfigurable Simple First-order Transfer Function

Advances in Electrical and Computer Engineering, 2015
Modified current differencing unit (MCDU) and its simple filtering application are introduced in this paper. Modification of the well-known current differencing unit consists in weighted difference of both input currents controlled by adjustable ...
SOTNER, R., JERABEK, J., HERENCSAR, N., ZAK, T., JAIKLA, W., VRBA, K.   +5 more
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Decision rules for robotic mobile fulfillment systems

Operations Research Perspectives, 2019
The Robotic Mobile Fulfillment Systems (RMFS) is a new type of robotized, parts-to-picker material handling system, designed especially for e-commerce warehouses.
M. Merschformann, T. Lamballais, M.B.M. de Koster, L. Suhl   +3 more
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source