Results 61 to 70 of about 395,319 (323)
FEBS Letters, EarlyView.Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile +8 more
wiley +1 more source
Neural ordinary differential equation control of dynamics on graphs
Physical Review Research, 2022 We study the ability of neural networks to calculate feedback control signals that steer trajectories of continuous-time nonlinear dynamical systems on graphs, which we represent with neural ordinary differential equations (neural ODEs).
Thomas Asikis +2 more
doaj +1 more source
Motion Planning of Uncertain Ordinary Differential Equation Systems [PDF]
, 2011 This work presents a novel motion planning framework, rooted in nonlinear programming theory, that treats uncertain fully and under-actuated dynamical systems described by ordinary differential equations.
Hays, Joe +3 more
core +1 more source
Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes
FEBS Letters, EarlyView.Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley +1 more source
, 2009 System of semilinear ordinary differential equation and fractional differential equation of distributed order is investigated and solved in a mild and classical sense.
Atanackovic, Teodor M. +2 more
core +1 more source
FEBS Letters, EarlyView.Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican +7 more
wiley +1 more source
On Nonlinear Dynamics of the STAT5a Signaling Protein
Biomath, 2014 In this paper we model the dynamics of the cross talk between MEK/ERK and JAK/STAT signaling pathways by means of nonlinear ordinary differential equations.
Elena Nikolova +2 more
doaj +1 more source
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
Method of the Logistic Function for Finding Analytical Solutions of Nonlinear Differential Equations
Моделирование и анализ информационных систем, 2015 The method of the logistic function is presented for finding exact solutions of nonlinear differential equations. The application of the method is illustrated by using the nonlinear ordinary differential equation of the fourth order. Analytical solutions
N. A. Kudryashov
doaj +1 more source
Numerical Solution of Stieltjes Differential Equations
Mathematics, 2020 This work is devoted to the obtaining of a new numerical scheme based on quadrature formulae for the Lebesgue–Stieltjes integral for the approximation of Stieltjes ordinary differential equations.
Francisco J. Fernández +1 more
doaj +1 more source