Results 61 to 70 of about 400,456 (327)

On Nonlinear Dynamics of the STAT5a Signaling Protein

open access: yesBiomath, 2014
In this paper we model the dynamics of the cross talk between MEK/ERK and JAK/STAT signaling pathways by means of nonlinear ordinary differential equations.
Elena Nikolova   +2 more
doaj   +1 more source

European Code Against Cancer, 5th edition – hormone replacement therapy, other common medical therapies and cancer

open access: yesMolecular Oncology, EarlyView.
The 5th edition of the European Code Against Cancer (ECAC5) contains 14 recommendations on cancer prevention. Here, we update the cancer prevention recommendations regarding the use of hormone replacement therapy (HRT), which is positioned as recommendation number 13 of the ECAC5.
Mangesh A. Thorat   +18 more
wiley   +1 more source

Method of the Logistic Function for Finding Analytical Solutions of Nonlinear Differential Equations

open access: yesМоделирование и анализ информационных систем, 2015
The method of the logistic function is presented for finding exact solutions of nonlinear differential equations. The application of the method is illustrated by using the nonlinear ordinary differential equation of the fourth order. Analytical solutions
N. A. Kudryashov
doaj   +1 more source

Modified Block Method for the Direct Solution of Second Order Ordinary Differential Equations [PDF]

open access: yes, 2011
The direct solution of general second order ordinary differential equations is considered in this paper. The method is based on the collocation and interpolation of the power series approximate solution to generate a continuous linear multistep method ...
Adebile, E.A.   +3 more
core  

A Recipe for State Dependent Distributed Delay Differential Equations

open access: yes, 2018
We use the McKendrick equation with variable ageing rate and randomly distributed maturation time to derive a state dependent distributed delay differential equation.
Cassidy, Tyler   +2 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Doubly Periodic Meromorphic Solutions of Autonomous Nonlinear Differential Equations

open access: yesМоделирование и анализ информационных систем, 2014
The problem of constructing and classifying elliptic solutions of nonlinear differential equations is studied. An effective method enabling one to find an elliptic solution of an autonomous nonlinear ordinary differential equation is described.
M. V. Demina, N. A. Kudryashov
doaj   +1 more source

Numerical Solution of Stieltjes Differential Equations

open access: yesMathematics, 2020
This work is devoted to the obtaining of a new numerical scheme based on quadrature formulae for the Lebesgue–Stieltjes integral for the approximation of Stieltjes ordinary differential equations.
Francisco J. Fernández   +1 more
doaj   +1 more source

Ermakov-Pinney and Emden-Fowler equations: new solutions from novel B\"acklund transformations

open access: yes, 2017
The class of nonlinear ordinary differential equations $y^{\prime\prime}y = F(z,y^2)$, where F is a smooth function, is studied. Various nonlinear ordinary differential equations, whose applicative importance is well known, belong to such a class of ...
Carillo, Sandra, Zullo, Federico
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

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