Results 171 to 180 of about 362,976 (244)

ALIGaToR: a tool for the automated annotation of immunoglobulin and T cell receptor genomic loci. [PDF]

Oxf Open Immunol
Schramm CA, Olubo S, Douek DC.
europepmc   +1 more source

Crucial Contribution of BACH1 to Bladder Cancer Progression via Upregulating Epithelial‐Mesenchymal Transition Pathway

Cancer Science, EarlyView.
BACH1 is associated with poor prognosis in BC patients and plays a critical role in promoting tumor progression and metastasis. Furthermore, we elucidated the mechanism by which BACH1 facilitates tumor progression and metastasis, primarily through activation of the EMT pathway. These findings suggest that BACH1 may serve as a novel prognostic biomarker
Tomoya Hatayama, Kenshiro Takemoto, Kohei Kobatake, Kento Miura, Liyanage P. Perera, Ryoken Yamanaka, Kazuma Yukihiro, Hiroyuki Shikuma, Kyosuke Iwane, Ryo Tasaka, Yuki Kohada, Miki Naito, Shunsuke Miyamoto, Yohei Sekino, Hiroyuki Kitano, Keisuke Goto, Akihiro Goriki, Keisuke Hieda, Osamu Kaminuma, Nobuyuki Hinata   +19 more
wiley   +1 more source

Insights into the architecture of earthworm metallothionein genes, powered by long-read genomics and transcriptomics. [PDF]

NAR Genom Bioinform
Karpov MA, Short S, Kille P, Hobbs C, Etxabe AG, Spurgeon DJ, Stürzenbaum SR.   +6 more
europepmc   +1 more source

A11 Peptide Enhances Radiosensitivity by Degrading EphA2 in Nasopharyngeal Carcinoma

Cancer Science, EarlyView.
In EphA2‐high‐expressing nasopharyngeal carcinoma cells, radiation triggers RSK‐dependent phosphorylation of EphA2 at Ser897, which in turn activates AKT and promote radioresistance. The A11 peptide breaks this signaling cascade by degrading EphA2 and blocking its S897 phosphorylation, thereby markedly enhancing radiosensitivity.
Ming Zhang, Zhi‐Qiang Xiao, Wei Huang, Shan‐Shan Lu, Hong Yi, Juan Feng   +5 more
wiley   +1 more source

A facial nodular orf infection in an HIV positive patient: Report of a case

Turkderm Turkish Archives of Dermatology and Venereology
Sema Aytekin, Burak Ekinci, Cansu Sönmez   +2 more
doaj   +1 more source

Mounting Evidence for an Expanded Host Range of Influenza B Viruses. [PDF]

Viruses
Koutsakos M, Parry RH, Wille M.
europepmc   +1 more source

Human Infection with Orf Virus from Goats in China, 2012

Vector Borne and Zoonotic Diseases, 2014
Keshan Zhang, Yongjie Liu, Han-jin Kong, Y. Shang, Xiang-tao Liu   +4 more
semanticscholar   +1 more source

LncRNA H19‐Encoded Micropeptide altH19 Promotes DNA Replication and Mitosis in Myeloma Cells by Enhancing the Phosphorylation of CDK2 at Threonine 160

Cell Proliferation, EarlyView.
The micropeptide altH19 interacts with phosphorylated CDK2 (p‐CDK2), subsequently activating CDK2 phosphorylation. This enhances the downstream E2F1 target gene RB activity, which accelerates DNA replication, ultimately leading to rapid myeloma cell mitosis and proliferation.
Yaxin Zhang, Wenjing Li, Xu Cao, Jiwei Mao, Xiaodan Zhou, Linlin Liu, Ruosi Yao   +6 more
wiley   +1 more source

Cyanobacteriochrome-like GAF folds in phages revealed via AlphaFold proteomic modelling. [PDF]

Comput Struct Biotechnol J
Meza-Padilla I, Doxey AC, Nissimov JI.
europepmc   +1 more source

Climate shocks, democratization and (a culture of) cooperation

Economica, EarlyView.
Abstract While the direct economic effects of adverse climate shocks are well known, their indirect institutional impact is still poorly understood. To clarify this, we test the idea that adverse climate shocks push time‐inconsistent elites to enact inclusive political institutions, and non‐elites to embrace strong norms of cooperation.
Giacomo Benati, Carmine Guerriero
wiley   +1 more source