Results 181 to 190 of about 467,774 (286)

VDJ-Insights: simplifying the annotation of genomic immunoglobulin and T cell receptor regions. [PDF]

Bioinformatics
Ott SE, Le GN, Mohammadi SJ, Mittertreiner J, Pasini EM, Bontrop RE, de Groot NG, Bruijnesteijn J.   +7 more
europepmc   +1 more source

Regulation of PHOX2B gene expression by the long non‐coding natural antisense RNA PHOX2B‐AS1

The FEBS Journal, EarlyView.
PHOX2B is a transcription factor essential for autonomic nervous system development. We identify and characterize PHOX2B‐AS1, a human long non‐coding antisense transcript at the PHOX2B locus, along with its murine counterpart. Our findings reveal bidirectional transcription and reciprocal regulation: PHOX2B activates PHOX2B‐AS1, whereas PHOX2B‐AS1 ...
Simona Di Lascio, Ana Lucia Cuadros Gamboa, Martina Bertocchi, Filippo Chiesa, Francesca Cargnin, Ettore Mosca, Paride Pelucchi, Viviana Tritto, Stefania Corti, Isabella Ceccherini, Paola Riva, Roberta Benfante, Diego Fornasari   +12 more
wiley   +1 more source

TRANSAID: a hybrid deep learning framework for translation site prediction with integrated biological feature scoring. [PDF]

Front Bioinform
Li Y, Wang B, Liu Z, Wei W, Fei C, Xu S, Han T, Geng W, Wu Z.   +8 more
europepmc   +1 more source

H2‐dependent modulation of tetrahydromethanopterin S‐methyltransferase (Mtr complex) activity by the small protein MtrR in Methanosarcina mazei

The FEBS Journal, EarlyView.
Small protein MtrR is a regulator of the Mtr methyltransferase complex in Methanosarcina mazei. It binds specifically to the MtrA subunit and modulates Mtr activity in response to hydrogen (H2) availability. Deleting mtrR impairs growth in the presence but not absence of H2, indicating its role in directing methyl transfer toward an energy‐conserving ...
Tim Habenicht, Bjarne Hastedt, Liam Cassidy, Claudia Kießling, Andreas Tholey, Jan M. Schuller, Ruth A. Schmitz   +6 more
wiley   +1 more source

Identification of hot spring Obelisk-like RNA replicons and expanded diversity of the Obelisk superfamily. [PDF]

Nat Commun
Urayama SI, Fukudome A, Mutz P, Matsushita Y, Takaki Y, Nishimura Y, Medvedeva S, Krupovic M, Koonin EV, Nunoura T.   +9 more
europepmc   +1 more source

A distinct gene expression mechanism for d‐amino acid utilization in hyperthermophilic archaeon Pyrococcus horikoshii

The FEBS Journal, EarlyView.
The genes PH0137, PH0138, and PH0140 form a cluster in the genome of Pyrococcus horikoshii. The PH0140 gene encodes a transcription factor identified as a d‐amino acid‐responsive regulatory protein (DARP). In feast mode, l‐Ile‐bound DARP binds to the promoter and represses transcription of PH0137 and PH0138. In famine mode, DARP binds to d‐allo‐Ile and
Ryushi Kawakami, Tomoki Kawase, Taira Uehara, Haruhiko Sakuraba, Tomohiko Matsuzawa, Junji Hayashi, Toshihisa Ohshima   +6 more
wiley   +1 more source

A new Epseptimavirus bacteriophage vB_SalS-SIY1lw as a potential antimicrobial alternative to multidrug-resistant Salmonella Infantis. [PDF]

Sci Rep
Liao YT, Voelker A, Arellano AR, Zhang Y, Harden LA, Salvador A, Wu VCH.   +6 more
europepmc   +1 more source

‘AN AUSTRIAN FATE’: TRAUMA, REPRESSION AND WAR IN ADRIAN GOIGINGER'S DER FUCHS (2022)

German Life and Letters, EarlyView.
ABSTRACT This article examines one of the highest‐grossing films in recent years in Austria, Der Fuchs (Adrian Goiginger, 2022), which focuses on the friendship of the protagonist, a Wehrmacht soldier, with an abandoned fox cub, but in the process elides more than four years of the soldier's wartime experience.
Katya Krylova
wiley   +1 more source

Corporate Sponsoring of the Council Presidency: A Research Agenda

JCMS: Journal of Common Market Studies, EarlyView.
Abstract Member states holding the Council Presidency routinely seek corporate sponsors. Typically, these sponsors offer free or discounted goods and services, such as food, beverages, cell phones, software or a car fleet in exchange for being labelled an official partner or sponsor of the Presidency.
Gijs Jan Brandsma, Reinout van der Veer
wiley   +1 more source