Results 161 to 170 of about 347,509 (295)

Relationship Between PTBP1 and Pancreatic Cancer Based on microRNA and Behavior During TYMS‐Mediated Carcinogenesis

Cancer Science, EarlyView.
Corresponding Author and colleagues identify a pancreas‐enriched microRNA, miR‐216b‐5p, that suppresses PTBP1 and its downstream effector TYMS. Their findings reveal a novel miR‐216b‐5p/PTBP1/TYMS regulatory axis driving pancreatic cancer progression and establish PTBP1 as a central molecular regulator of tumor biology beyond its metabolic role ...
Shigenori Suzuki, Hiroaki Hase, Yosuke Inomata, Jun Arima, Kentaro Jingushi, Atsushi Tomioka, Nao Kawaguchi, Hiroki Hamamoto, Ryo Tanaka, Yoshiro Imai, Mitsuhiro Asakuma, Tomohito Tanaka, Kazutake Tsujikawa, Kohei Taniguchi, Sang‐Woong Lee   +14 more
wiley   +1 more source

Overcoming Subjectivity in Bandgap Evaluation through On-Resonance Fluorescence: Establishing a Robust and Objective Optical Metric for Fluorescent Materials. [PDF]

ACS Meas Sci Au
Pham H, Yan R, McEachin J, Zou S, Zhang D.   +4 more
europepmc   +1 more source

Monitoring wildlife health for diseases with visible signs by integrating camera traps with marked individuals

Conservation Biology, EarlyView.
Abstract Monitoring wildlife health is essential for conservation and management, wildlife and livestock welfare, and public health in a One Health framework. Yet, wildlife health monitoring often requires long‐term fieldwork and intensive sampling, which can be costly or logistically challenging, especially for remote, rare, or elusive populations. To
Jonathan Tichon, Roi Lapid, Roni King, Elyasaf Freiman, Orr Spiegel, Erez Baruchi, Aviam Atar, Shirli Bar‐David, David Saltz   +8 more
wiley   +1 more source

Etymologia: Orf

Emerging Infectious Diseases, 2013
doaj   +1 more source

Enhancer RNAs: similarities with both lncRNAs and mRNAs reveal novel functions. [PDF]

RNA Biol
Vlasov PA, Manley JL.
europepmc   +1 more source

Shikimate pathway disruption in yeast induces metabolite self‐assembly into toxic aggregates

The FEBS Journal, EarlyView.
In Saccharomyces cerevisiae, shikimate pathway disruption induces toxic metabolite assemblies. Deleting ARO4 plus phenylalanine (Phe) feeding causes Phenylalanine accumulation, lowers ARO3 activity, and triggers amyloid‐like fibril formation. Deleting ARO3 plus tyrosine (Tyr) feeding leads to Tyrosine buildup and similar fibril assembly.
Hanaa Adsi, Myra Gartner, Claris Simovich, Lihi Gershon, Alexander Brandis, Ehud Gazit, Dana Laor Bar‐Yosef   +6 more
wiley   +1 more source

Enrichment and Reduction of Microsatellite Regions in the Myxoma Virus Genome Following Species Jump to the Iberian Hare (<i>Lepus granatensis</i>). [PDF]

Transbound Emerg Dis
Menéndez-Manjón A, Cardoso B, Castro-Scholten S, Agüero M, Duran M, Buitrago D, Lopes AM, Abrantes J, Martinez-Haro M, Cano-Terriza D, Jiménez-Martín D, Camacho-Sillero L, Nicieza I, Arenas-Vicente S, Calonge-Sanz I, Parra F, Alvarez AL, Domínguez P, Martín-Alonso JM, García-Bocanegra I, Dalton KP.   +20 more
europepmc   +1 more source

Digitale Demokratie und Öffentlich-Rechtliche Medien [Digital Democracy and Public Service Media]. In ORF Public Value Studie 2017/2018: Der Auftrag: Demokratie [ORF Public Value Study 2017/2018: The Mission: Democracy]

, 2018
Fuchs, Christian
core  

H2‐dependent modulation of tetrahydromethanopterin S‐methyltransferase (Mtr complex) activity by the small protein MtrR in Methanosarcina mazei

The FEBS Journal, EarlyView.
Small protein MtrR is a regulator of the Mtr methyltransferase complex in Methanosarcina mazei. It binds specifically to the MtrA subunit and modulates Mtr activity in response to hydrogen (H2) availability. Deleting mtrR impairs growth in the presence but not absence of H2, indicating its role in directing methyl transfer toward an energy‐conserving ...
Tim Habenicht, Bjarne Hastedt, Liam Cassidy, Claudia Kießling, Andreas Tholey, Jan M. Schuller, Ruth A. Schmitz   +6 more
wiley   +1 more source

A distinct gene expression mechanism for d‐amino acid utilization in hyperthermophilic archaeon Pyrococcus horikoshii

The FEBS Journal, EarlyView.
The genes PH0137, PH0138, and PH0140 form a cluster in the genome of Pyrococcus horikoshii. The PH0140 gene encodes a transcription factor identified as a d‐amino acid‐responsive regulatory protein (DARP). In feast mode, l‐Ile‐bound DARP binds to the promoter and represses transcription of PH0137 and PH0138. In famine mode, DARP binds to d‐allo‐Ile and
Ryushi Kawakami, Tomoki Kawase, Taira Uehara, Haruhiko Sakuraba, Tomohiko Matsuzawa, Junji Hayashi, Toshihisa Ohshima   +6 more
wiley   +1 more source