Results 21 to 30 of about 359,848 (279)

A Violently Tornadic Supercell Thunderstorm Simulation Spanning a Quarter-Trillion Grid Volumes: Computational Challenges, I/O Framework, and Visualizations of Tornadogenesis

open access: yesAtmosphere, 2019
Tornadoes remain an active subject of observational and numerical research due to the damage and fatalities they cause worldwide as well as poor understanding of their behavior, such as what processes result in their genesis and what determines their ...
Leigh Orf
doaj   +1 more source

Climate-Resilient Infrastructure as a Public Good: Welfare, Risk, and Climate-Smart Growth

open access: yesChallenges
Climate change has emerged as a defining global crisis, with the frequency and intensity of climate-induced disasters rising sharply and imposing disproportionate costs on developing economies and small island states.
Manish Vaidya, Soumya Bhowmick
doaj   +1 more source

Investigation of the complications and incidences of orf disease during and after the Feast of the Sacrifice period

open access: yesDermatologica Sinica, 2015
Background/objectives: Orf is not an endemic disease. However, it causes epidemics after the Feast of the Sacrifice in Muslim countries because it is transmitted from animals.
Handan Saçar   +3 more
doaj   +1 more source

Orf (ecthyma contagiosum)

open access: yesThe Pan African Medical Journal, 2021
Orf, also known as ecthyma contagiosum, is a parapox virus infection endemic among sheep and goats that can be transmitted to humans particularly to farmers, sheepherders, butchers and veterinarians. Although it’s a self-limiting infection, complications
Konstantina Mavridou, Maria Bakola
doaj   +1 more source

Antibiotic Resistance Profile in Co-Infecting Bacteria Isolated from Sheep Dipslaying Orf Lesions

open access: yesBulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca: Veterinary Medicine, 2020
Antibiotic resistance in veterinary medicine poses lately increasing risks in therapeutic success and threatens the life of patients with various bacterial infections.
Elisabeta PASTOR   +3 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Biochemical analysis of bacteriophage Orf family recombinases [PDF]

open access: yes, 2012
Bacterial pathogen evolution is an important field of study in light of the emergence of new diseases and drug resistant strains. Genomic rearrangements facilitated by temperate bacteriophages provide a major route for bacteria to acquire new pathogenic ...
WALLACE, IAIN,DAVID
core  

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Şâfiî Mezhebinde Örf ve Âdetin Yeri ve Kaynak Değeri

open access: yesİslam Medeniyeti Araştırmaları Dergisi, 2023
Hukukun sosyal hayata uyumunu sağlayan örf ve âdet usul kurallarının belirlenmesi ve fıkhî meselelere çözümler sunması noktasında başvurulması gereken sosyal normdur.
Mehmet Selim Aslan
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

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