Results 121 to 130 of about 122,503 (234)

Inhibition of PHF1 promotes ferroptosis via IRES‐dependent Snail translation regulation in pancreatic ductal adenocarcinoma

open access: yesVIEW, Volume 7, Issue 3, June 2026.
PHF1 is a known epigenetic regulator involved in transcriptional silencing in cancer. In this study, we identified PHF1 as an oncogene that promotes PDAC progression and demonstrated that its inhibition induces ferroptosis. Mechanistically, PHF1 physically interacts with the FBL/NOP56/NOP58 snoRNP complex to enhance the IRES‐dependent translation of ...
Yujiao Xie   +9 more
wiley   +1 more source

Use of a Local Anaesthetic/Antiseptic Formulation for the Treatment of Lambs Experimentally Infected with Orf Virus. [PDF]

open access: yesAnimals (Basel), 2023
Lacasta D   +12 more
europepmc   +1 more source

New Finnlakevirus Isolate FLiP‐2 Provides Insight Into the Ecology of ssDNA Phages in Flavobacterium Hosts

open access: yesEnvironmental Microbiology, Volume 28, Issue 6, June 2026.
Despite the small genome size, ssDNA virus FLiP is remarkably well adapted to the seasonal variations of boreal fresh waters demonstrating excellent condition and host specific flexibility in its host interactions. FLiP plaques detected far from the original infection site represent a previously undescribed phenomenon, likely caused by the phage non ...
Kati Mäkelä   +5 more
wiley   +1 more source

The whole genome analysis of four Orf virus strains from Europe and South America. [PDF]

open access: yesVirus Evol
Cacciabue M   +8 more
europepmc   +1 more source

Isolation of a Novel Lytic Pseudomonas aeruginosa Phage Henu5 and Fitness Costs of Phage‐Driven Resistance

open access: yesMicrobial Biotechnology, Volume 19, Issue 6, June 2026.
This study isolated and identified a novel lytic phage that infects Pseudomonas aeruginosa. Henu5 exhibited good physicochemical stability. Additionally, the phage‐resistant mutants showed fitness trade‐offs in growth, virulence and antibiotic susceptibility, along with in vivo fitness, which might direct future phage selection in clinical settings ...
Salwa E. Gomaa   +7 more
wiley   +1 more source

Spiroplasma Are Protective Heritable Symbionts With Low Physiological Impact in the Drosophilid Fly Zaprionus kolodkinae

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 3, June 2026.
Zaprionus kolodkinae flies carry a maternally inherited ixodetis clade Spiroplasma that protects its host against wasp attack but has low overall physiological impact. Genome analysis presented a set of known symbiosis‐relevant effectors, and one encoding—a ricin B domain protein—that is novel to this Spiroplasma genome.
Nuha Alamer   +5 more
wiley   +1 more source

Regulation of PHOX2B gene expression by the long non‐coding natural antisense RNA PHOX2B‐AS1

open access: yesThe FEBS Journal, Volume 293, Issue 12, Page 3502-3527, June 2026.
PHOX2B is a transcription factor essential for autonomic nervous system development. We identify and characterize PHOX2B‐AS1, a human long non‐coding antisense transcript at the PHOX2B locus, along with its murine counterpart. Our findings reveal bidirectional transcription and reciprocal regulation: PHOX2B activates PHOX2B‐AS1, whereas PHOX2B‐AS1 ...
Simona Di Lascio   +12 more
wiley   +1 more source

Rapid Onsite Visual Detection of Orf Virus Using a Recombinase-Aided Amplification Assay. [PDF]

open access: yesLife (Basel), 2023
Cui H   +8 more
europepmc   +1 more source

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