Results 141 to 150 of about 1,177,046 (259)

Human Orf Disease; a case series in Kashan City, Iran

International Archives of Health Sciences, 2015
Aims Infection with parapoxvirus is an occupational hazard of farm workers, abattoir workers, veterinarians, and others with frequent exposure to sheep, cattle, or goats.
Afzali H.1 MD,, Momen–Heravi M.* MD
doaj  

Nucleases and Their Inhibitors: Exploring Biological Roles, Industrial Applications, and Challenges in Heterologous Expression

Biotechnology Journal, Volume 21, Issue 9, September 2026.
Graphical Abstract and Lay Summary Intracellular nucleases, depicted as blue circles in a nucleosome, hydrolyze phosphodiester bonds, repair damaged DNA using DNA base excision repair (BER), mismatch repair (MMR), and homologous recombination (HR), and are involved in DNA replication.
Wian Vermeulen, Anton Du Preez van Staden, Leon M. T. Dicks   +2 more
wiley   +1 more source

Microproteins as a Hidden Player in Breast Cancer: From Molecular Insights to Therapeutic Potential

Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT Breast cancer continues to pose a public health problem and is the second leading cause of cancer‐related mortality among women globally. Despite advances in our understanding of cancer biology and the development of treatment strategies, the therapeutic response is not often satisfactory as treatment efficacy is limited by severe side effects
Qianyi Dai, Kimberly Seaman, Xin Song, Amel Sassi, Xiaolong Yang, Lidan You   +5 more
wiley   +1 more source

Endogenous Bornavirus‐Like Nucleoprotein 1 Regulates Cellular Processes and DNA Double‐Strand Breaks in U‐87 MG Glioblastoma Cells

Cancer Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background Glioblastoma (GBM) is a common brain cancer with a poor prognosis and a high recurrence rate. DNA damage repair plays a crucial role in GBM carcinogenesis and treatment resistance. Human endogenous bornavirus‐like nucleoprotein 1 (EBLN1) regulates cellular processes and genetic stability. However, the biological role of EBLN1 in GBM
Jing Liang, Dongdong Zeng, Yujie Guo, Cuiyuan Jing, Lin Tang, Zhanpeng Luo, Peng He   +6 more
wiley   +1 more source

mRNA Therapeutics Beyond Infectious Diseases: Expanding Therapeutic Applications and Future Perspectives

Immunity, Inflammation and Disease, Volume 14, Issue 9, September 2026.
Messenger RNA therapeutics are rapidly expanding beyond infectious diseases into oncology, autoimmune disorders, protein replacement therapy, cardiovascular and neurological diseases, and regenerative medicine. Advances in RNA engineering and targeted delivery are driving the development of safe, programmable, and precision therapeutics for diverse ...
Gedion Mengistu Dejen
wiley   +1 more source

Viruses in the sediments around the trenches harbor diverse survival mechanisms

iMetaOmics, Volume 3, Issue 3, September 2026.
Deep‐sea trenches are the deepest and most isolated environments in the global ocean but the diversity and adaptation of the viral communities remain poorly characterized. In this study, 5563 viral operational taxonomic units (vOTUs) were identified from sediments of the Yap Trench and Western Caroline Basin.
Yue Su, Hao Yu, Shujuan Sun, Kaiyang Zheng, Ziyue Wang, Chen Gao, Guangxue Li, Xiaoshou Liu, Hongbing Shao, David Paez‐Espino, Andrew McMinn, Yantao Liang, Min Wang   +12 more
wiley   +1 more source

Smart Design: Integrating Artificial Intelligence and Gene Editing for Advanced mRNA Therapeutics

MedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.
The challenges of mRNA therapy and the application of artificial intelligence and gene editing in the field of mRNA drugs. ABSTRACT Artificial intelligence (AI) and gene editing are increasingly being applied to the design and evaluation of mRNA therapeutics.
Haixing Shi, Shengbin Liu, Danni Dai, Shanhui Jiang, Tingchen Tian, Zhenyi Niu, Zhongzheng Xiang, Chaoyu Zou, Fang Liu, Xue Tang, Xin Jiang, Xiangrong Song   +11 more
wiley   +1 more source

High‐Content CRISPR Screening: Methods and Applications

MedComm, Volume 7, Issue 9, September 2026.
High‐content CRISPR screening represents a paradigm shift in functional genomics, moving beyond traditional survival‐based readouts to enable multidimensional mapping of genotype–phenotype relationships. This review systematically outlines the methodological evolution of this approach, detailing advances in perturbation modalities, delivery systems ...
Yike Zhang, Yimeng Zhang, Xudong Tang, Xinyu Deng, Yitian Zhou, Yanfeng Wu, Jianhua Luo   +6 more
wiley   +1 more source

Atypical case of an orf virus infection in sheep. [PDF]

BMC Vet Res
Segna A, Portobanco Villalobos ID, Ganter M, Ludlow M, Baumgärtner W, Gregor KM.   +5 more
europepmc   +1 more source

Turnip Mosaic Virus‐Based gRNA Delivery System for Plant Genome Editing

Plant Direct, Volume 10, Issue 9, September 2026.
ABSTRACT Plant virus‐based gRNA delivery systems offer a rapid alternative to stable transformation for CRISPR‐mediated genome editing, but potyvirus‐based platforms in Cas9‐expressing plants are still underexplored. Here, we developed a turnip mosaic virus (TuMV)‐based system for gRNA delivery in Cas9‐expressing Nicotiana benthamiana and tested ...
Ekkachai Khwanbua, Ryan R. Lappe, Austin A. Bierl, Steven A. Whitham   +3 more
wiley   +1 more source