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Novel Multi-Antigen Orf-Virus-Derived Vaccine Elicits Protective Anti-SARS-CoV-2 Response in Monovalent and Bivalent Formats. [PDF]
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Reviews in Medical Virology, 2017
SummaryOrf virus (ORFV) is an important pathogen responsible for a highly contagious zoonotic viral infection that threatens those who handle sheep and goats. Orf virus is the prototype of the Parapoxvirus genus, and its resilience in the environment and ability to reinfect its host has contributed to the spread and maintenance of the infection in many
Christina Bergqvist +2 more
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SummaryOrf virus (ORFV) is an important pathogen responsible for a highly contagious zoonotic viral infection that threatens those who handle sheep and goats. Orf virus is the prototype of the Parapoxvirus genus, and its resilience in the environment and ability to reinfect its host has contributed to the spread and maintenance of the infection in many
Christina Bergqvist +2 more
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Virology, 1964
Abstract Three methods can be used to show that both upper and lower surfaces of orf virus particles are seen in sodium phosphotungstate-stained electron micrographs. These have demonstrated that the characteristic tubular thread structure of the wall of the particle is in the form of a left-hand spiral coil of a single thread.
J, NAGINGTON, A A, NEWTON, R W, HORNE
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Abstract Three methods can be used to show that both upper and lower surfaces of orf virus particles are seen in sodium phosphotungstate-stained electron micrographs. These have demonstrated that the characteristic tubular thread structure of the wall of the particle is in the form of a left-hand spiral coil of a single thread.
J, NAGINGTON, A A, NEWTON, R W, HORNE
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Ocular Infection with Orf Virus
American Journal of Ophthalmology, 1984Orf virus infection of the pericanthal eyelid skin and conjunctiva was diagnosed by electron microscopy. Orf is a paravaccinia virus responsible for contagious pustular dermatitis in sheep and goats. It occasionally affects humans. The patient was a farmwife who had recently handled lambs.
G, Freeman, A J, Bron, B, Juel-Jensen
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2020
Capripox infections of small ruminants, namely goatpox and sheeppox, are OIE notifiable and transboundary animal diseases. Goatpox and sheeppox are prevalent in some parts of Africa, the Middle East, and Asia with occasional outbreaks in regions of Europe.
Gnanavel Venkatesan +4 more
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Capripox infections of small ruminants, namely goatpox and sheeppox, are OIE notifiable and transboundary animal diseases. Goatpox and sheeppox are prevalent in some parts of Africa, the Middle East, and Asia with occasional outbreaks in regions of Europe.
Gnanavel Venkatesan +4 more
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Conservation and variation in orf virus genomes
Virology, 1987The genomes of several orf virus strains were analyzed with the restriction endonucleases EcoRI, HindIII, BamHI, and KpnI, and cleavage site maps were deduced. In general, the right half of the genome showed conservation of restriction sites compared with the left half.
A J, Robinson +4 more
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The structure and cloning of orf virus DNA
Virology, 1987A map of cleavage sites for the restriction endonucleases EcoRI, HindIII, BamHI, HpaI, and KpnI for a New Zealand strain of orf virus (NZ2) DNA has been deduced. Also, the entire genome, apart from approximately 0.1 kbp at each end, has been cloned into various vectors.
A A, Mercer +3 more
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Orf virus infection in sheep or goats
Veterinary Microbiology, 2015Orf virus, a member of the genus Parapoxvirus, is the causative agent of contagious ecthyma ('Orf'). It is a pathogen with worldwide distribution, causing significant financial losses in livestock production. The disease mainly affects sheep and goats, but various other ruminants and mammals have been reported to be infected as well.
V, Spyrou, G, Valiakos
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Cytokines and their inhibitors in orf virus infection
Veterinary Immunology and Immunopathology, 1996The epitheliotropic parapoxvirus, orf virus, can repeatedly infect sheep skin. A specific immune response is generated as reinfections induce smaller lesions with quicker resolution times than primary lesions. Cyclosporin-A treatment abrogates this partial immunity.
D, Haig +10 more
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The immune and inflammatory response to orf virus
Comparative Immunology, Microbiology and Infectious Diseases, 1997Orf virus is a zoonotic, epitheliotropic DNA parapox virus that principally infects sheep and goats. The fact that the virus can repeatedly reinfect sheep has provoked an interest in the underlying cellular, virological and molecular mechanisms for its apparent escape from the host protective immune response.
D M, Haig +4 more
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