Results 81 to 90 of about 1,888,313 (328)

The SARS-coronavirus-host interactome [PDF]

, 2011
Coronaviruses (CoVs) are important human and animal pathogens that induce fatal respiratory, gastrointestinal and neurological disease. The outbreak of the severe acute respiratory syndrome (SARS) in 2002/2003 has demonstrated human vulnerability to ...
Brunn, Albrecht von, Carbajo-Lozoya, Javier, Dall'Armi, Ekatarina von, Ditt, Vanessa, Drosten, Christian, Friedel, Caroline C., Haas, Juergen G., Herrler, Georg, Herzog, Petra, Hilgenfeld, Rolf, Kallies, Stefan, Kuri, Thomas, Kögl, Manfred, Müller, Marcel A., Niemeyer, Daniela, Pfefferle, Susanne, Pumpor, Ksenia, Pöhlmann, Stefan, Schwarz, Frank, Schwegmann-Wessels, Christel, Schöpf, Julia, Steffen, Imke, Stellberger, Thorsten, Thiel, Heinz-Jürgen, Thiel, Volker, Weber, Friedemann, Zimmer, Ralf, Züst, Roland   +27 more
core   +1 more source

CRISPR/Cas9 editing of endogenous banana streak virus in the B genome of Musa spp. overcomes a major challenge in banana breeding [PDF]

, 2020
Open Access Journal; Published online: 31 Jan 2019Presence of the integrated endogenous banana streak virus (eBSV) in the B genome of plantain (AAB) is a major challenge for breeding and dissemination of hybrids.
Britt, A., Muiruri, S.K., Ntui, V.O., Ron, M., Tripathi, J.N., Tripathi, L.   +5 more
core   +1 more source

Orf virus encodes a functional dUTPase gene

Journal of General Virology, 2002
The present study is the first report on the functional activity of a parapoxvirus-encoded dUTPase. The dUTPase gene of the attenuated orf virus (ORFV), strain D1701, was expressed as a bacterial thioredoxin fusion protein.In vitroassays showed that ORFV dUTPase was highly specific for dUTP as substrate.
R, Cottone, M, Büttner, C J, McInnes, A R, Wood, H-J, Rziha   +4 more
openaire   +2 more sources

A genetic study of SSV1, the prototypical fusellovirus.

Frontiers in Microbiology, 2012
Viruses of thermophilic Archaea are unique in both their structures and genomic sequences. The most widespread and arguably best studied are the lemon-shaped fuselloviruses.
Eric eIverson, Kenneth eStedman
doaj   +1 more source

Orf virus infection in Alaskan mountain goats, Dall’s sheep, muskoxen, caribou and Sitka black-tailed deer

Acta Veterinaria Scandinavica, 2018
BackgroundThe zoonotic Orf virus (ORFV; genus Parapoxvirus, Poxviridae family) occurs worldwide and is transmitted between sheep and goats, wildlife and man.
M. Tryland, K. Beckmen, K. Burek‐Huntington, E. Breines, J. Klein   +4 more
semanticscholar   +1 more source

Decoding Triphenotypic Neutrophils in Cervical Cancer Evolution and Targeting SPP1+/GBP1+/ELOVL5+ Tumor‐Associated Neutrophils to Sensitize Immunotherapy

Advanced Science, EarlyView.
The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang, Xinyu Qu, Tingting Ren, Tong Wu, Weiyong Gu, Jingxin Ding, Keqin Hua, Junjun Qiu   +7 more
wiley   +1 more source

Analysis of a new negevirus-like sequence from Bemisia tabaci unveils a potential new taxon linking nelorpi- and centiviruses.

PLoS ONE
This study presents the complete genome sequence of a novel nege-like virus identified in whiteflies (Bemisia tabaci MEAM1), provisionally designated as whitefly negevirus 1 (WfNgV1).
Diego F Quito-Avila, Edison Reyes-Proaño, Gerardo Armijos-Capa, Ricardo I Alcalá Briseño, Robert Alvarez, Francisco F Flores   +5 more
doaj   +1 more source

The role of the Cucumber mosaic virus 2b protein in viral movement and symptom induction [PDF]

, 2009
The Cucumber mosaic virus (CMV) 2b protein is a counter-defense factor and symptom determinant. Conserved domains in the 2b protein sequence were mutated in the 2b gene of strain Fny-CMV.
Chen H.-Y., Fiona C. Robertson, Ham B.-K., Heiko Ziebell, John A. Walsh, John P. Carr, Ki Hyun Ryu, Lot H., Mathew Lewsey, Monique Surette, Palukaitis P., Peter Palukaitis, Roossinck M. J., Sun Hee Choi, Tina Payne, Tomas Canto   +15 more
core   +2 more sources

Cyclophilin B facilitates the replication of Orf virus [PDF]

Virology Journal, 2017
Viruses interact with host cellular factors to construct a more favourable environment for their efficient replication. Expression of cyclophilin B (CypB), a cellular peptidyl-prolyl cis-trans isomerase (PPIase), was found to be significantly up-regulated.
Kui Zhao, Jida Li, Wenqi He, Deguang Song, Ximu Zhang, Di Zhang, Yanlong Zhou, Feng Gao   +7 more
openaire   +3 more sources

Treatment of limb wounds of horses with orf virus IL-10 and VEGF-E accelerates resolution of exuberant granulation tissue, but does not prevent its development

PLoS ONE, 2018
Bandaging of limb wounds in horses leads to formation of exuberant granulation tissue (EGT) that retards healing due to protracted inflammation, aberrant vascularisation and delayed epithelialisation.
Lyn M. Wise, C. Bodaan, Gabriella S. Stuart, N. Real, Zabeen Lateef, A. Mercer, C. B. Riley, C. Theoret   +7 more
semanticscholar   +1 more source