Results 91 to 100 of about 122,503 (234)

Advances in large DNA fragment assembly for microbial cell factory engineering

open access: yesQuantitative Biology, Volume 14, Issue 3, September 2026.
Abstract The efficient, rapid, and reliable assembly of DNA fragments is essential for advancing metabolic engineering and synthetic biology. With the rapid advancement of DNA synthesis and assembly technologies, the scale of DNA assembly has expanded from single genes to metabolic pathways and even genomes.
Yu Zhang   +5 more
wiley   +1 more source

Astrocytic mGluR5 Regulation of Synaptic Transmission is Activity‐Dependent in Adult Rats

open access: yesGlia, Volume 74, Issue 8, August 2026.
In adulthood, astrocytic mGluR5 increases synaptic efficacy through presynaptic A2ARs. This occurs when a small number of synapses are activated simultaneously. This pathway is abolished when numerous synapses are recruited. ABSTRACT Data accumulated over the last two decades have demonstrated that astrocytes play key roles in the regulation of ...
Sarah Mountadem   +18 more
wiley   +1 more source

Spontaneous regression of equine sarcoids is an exceptional event

open access: yesEquine Veterinary Journal, Volume 58, Issue 4, Page 889-894, July 2026.
Abstract Sarcoids are benign, yet locally aggressive skin tumours that commonly affect horses and other equid species. The lesions are induced by bovine papillomavirus types 1, 2, and probably 13 in conjunction with other factors including trauma and a genetic predisposition.
Sabine Brandt
wiley   +1 more source

Epoxy Clerodane Diterpene Attenuates the Differentiated Adipocyte Hypertrophy and Enhances Mitochondrial Metabolism

open access: yesChemistryOpen, Volume 15, Issue 7, July 2026.
Epoxy Clerodane Diterpene (ECD) significantly reduces adipocyte hypertrophy and lipid accumulation in human mesenchymal stem cell (hMSC)‐derived adipocytes. ECD improves mitochondrial membrane potential (ΔΨm), increases thermogenic regulators (UCP‐1, PPARγC1α), decreases adipogenic markers (C/EBPα, PPARγ), and reduces inflammatory mediators (TNF‐α, NF ...
Sahar Abdulaziz AlSedairy   +4 more
wiley   +1 more source

Endoplasmic reticulum stress and the unfolded protein response in lung diseases: molecular pathways and therapeutic interventions

open access: yesThe Journal of Pathology, Volume 269, Issue 3, Page 268-283, July 2026.
Abstract Endoplasmic reticulum stress (ERS) occurs when the protein‐folding capacity of the endoplasmic reticulum (ER) is overwhelmed, triggering the unfolded protein response (UPR) to restore homeostasis. However, severe or persistent ERS can shift the UPR toward pro‐inflammatory, apoptotic, and fibrotic signaling, thereby exacerbating tissue injury ...
Lanlan Song   +6 more
wiley   +1 more source

RNA interference in crop protection: opportunities and challenges during the transition to commercialization

open access: yesPest Management Science, Volume 82, Issue 7, Page 5971-5986, July 2026.
RNA interference (RNAi) technologies, host‐induced gene silencing (HIGS) and spray‐induced gene silencing (SIGS), potentially offer sustainable crop protection. However, efficacy, costs, regulatory clarity, and socio‐environmental impacts require further evaluation for broader use.
Elisabetta Sergi   +12 more
wiley   +1 more source

Molecular Characterisation of Orf Virus in Goats From Eastern Türkiye

open access: yesVeterinary Medicine and Science, Volume 12, Issue 4, July 2026.
This study provides the molecular characterisation of Orf virus (ORFV) strains circulating in Türkiye. Phylogenetic analysis of F1L, B2L, and VIR genes reveals high genetic similarity with Asian and global isolates, highlighting the importance of multi‐gene analysis in monitoring viral outbreaks and understanding disease origins.
Remziye Özbek   +2 more
wiley   +1 more source

Afrina barna-like Virus, a Novel Virus Associated with Afrina sporoboliae, the Drop Seed Gall-Forming Nematode

open access: yesViruses
A novel barna-like virus was found to be associated with field-collected Afrina sporoboliae plant-parasitic nematodes. The positive-sense, single-stranded RNA genome of this virus, named Afrina barna-like virus (AfBLV), comprises 4020 nucleotides ...
Edison Reyes-Proaño   +6 more
doaj   +1 more source

Cucumber green mottle mosaic virus: A persistent seed‐borne threat to cucurbits

open access: yesAnnals of Applied Biology, Volume 189, Issue 1, July 2026.
Cucumber green mottle mosaic virus (CGMMV) is a highly stable, seed‐borne tobamovirus that threatens global cucurbit production. Its efficient mechanical and seed transmission, long‐term environmental persistence, and the spread of Clade II CGMMV isolates drive its rapid dissemination and cause severe yield losses.
Esperanza Gea‐Caballero   +1 more
wiley   +1 more source

Detection and molecular characterisation of beet chlorosis virus in sugar beet in the Czech Republic

open access: yesAnnals of Applied Biology, Volume 189, Issue 1, July 2026.
Beet chlorosis virus (BChV) was detected for the first time in Czech sugar beet, and its diversity was assessed. One‐enzyme RTX‐PCR screened 37 symptomatic plants from 15 fields, and BChV was found in 12 plants. Twelve isolates were confirmed by Sanger sequencing of the readthrough domain (RTD), while one representative isolate was sequenced by high ...
Emad Ibrahim   +5 more
wiley   +1 more source

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