Results 81 to 90 of about 126,031 (209)

Selective excitatory effects of γ‐glutamyl‐glycine, a glutathione metabolite, on GluN1 NMDA and mGlu5 receptors impacting synaptic plasticity

British Journal of Pharmacology, EarlyView.
Background and Purpose Gamma‐glutamyl dipeptides are essentially produced after glutathione (GSH) degradation. While several γ‐glutamyl dipeptides have been detected in different organs and body fluids, their biological activity remains elusive. This is the case for γ‐Glutamyl‐Glycine (γ‐Glu‐Gly) which has been found in different brain areas.
Sandro Andreu, Victoria Gizzi, Ugo Pasco, Fatiha Sebih, Yattou Zitouni, Pablo Jimenez, Valérie Rolland, Alain Chavanieu, Sébastien Estaran, Matthieu Rousset, Thierry Cens, Guillaume Cazals, Pierre Charnet, Janique Guiramand, Catherine Cohen‐Solal, Claudine Ménard, Marie‐Céleste de Jésus Ferreira, Nathalie Chevallier, Sonia Cantel, Michel Vignes, Julien Roussel   +20 more
wiley   +1 more source

Rescue of pATOM36‐depleted T. brucei by human MTCH1/2 reveals common features of protein insertases

The FEBS Journal, EarlyView.
Human MTCH1 and MTCH2 (with an N‐terminal extension) functionally complement the loss of pATOM36 in T. brucei, indicating that these evolutionarily distant proteins recognize a common set of substrates and share fundamental principles of mitochondrial outer membrane protein insertion. Structural analyses reveal a common hydrophilic cavity, supporting a
Stephan Berger, Markus Daniel Gerber, Torsten Ochsenreiter, Christoph von Ballmoos, André Schneider   +4 more
wiley   +1 more source

Variable Infection Outcomes in Repeated Experimental Challenges of Atlantic Salmon (Salmo salar) With an Infectious Salmon Anaemia Virus Isolate

Journal of Fish Diseases, EarlyView.
ABSTRACT Infectious salmon anaemia (ISA) affects Atlantic salmon (Salmo salar) and is caused by the ISA virus (ISAV). The disease is associated with ISAV strains with deletions in the hemagglutinin‐esterase protein, named HPRΔ variants. The present study was initially designed as a vaccine efficacy study against ISA.
Lars Ole Sti Dahl, Stine Braaen, Øystein Wessel, Johanna Hol Fosse, Espen Rimstad   +4 more
wiley   +1 more source

SlBPC1 regulates fruit elongation by directly repressing SlOFP2/SlOFP21 and SUN expression in tomato

Journal of Integrative Plant Biology, EarlyView.
In tomato, switching off the transcription factor gene SlBPC1 leads to longer fruits by altering cell division patterns during early fruit development. The SlBPC1 regulatory pathway includes the SlOFP2, SlOFP21, and SUN genes, offering valuable targets for breeding tomatoes with market‐preferred shapes.
Sunan Gao, Long Cui, Licheng Xiao, Rong Huang, Jing Wei, Chunrui Chen, Wenran Su, Jiajun Ran, Lei Song, Jingyi Li, Taotao Wang, Zonglie Hong, Zhibiao Ye, Jie Ye, Junhong Zhang   +14 more
wiley   +1 more source

Metagenomic detection and characterization of RNA viruses associated with Rhipicephalus linnaei (Audouin, 1826) ticks from the Amazon, Pará, Brazil

Medical and Veterinary Entomology, EarlyView.
Metagenomic analysis of Rhipicephalus linnaei from the Brazilian Amazon revealed the presence of RNA viruses belonging to the families Chuviridae, Phenuiviridae, Orthomyxoviridae and Rhabdoviridae. This study reports the first detection of Brown dog tick mivirus 1 and Brown dog tick phlebovirus 2 in Brazil, based on genomic characterization and ...
Lucas Henrique da Silva e Silva, Sandro Patroca da Silva, Fábio Silva da Silva, Leonardo Henrique Almeida Hernández, Daniel Damous Dias, Sâmia Luzia Sena da Silva, Lúcia Aline Moura Reis, Hanna Carolina Farias Reis, Bruna Laís Sena do Nascimento, Roberto Carlos Feitosa Brandão, Durval Bertram Rodrigues Vieira, Bruno Tardelli Diniz Nunes, Ana Cecília Ribeiro Cruz, Joaquim Pinto Nunes Neto   +13 more
wiley   +1 more source

Verticillium dahliae CFEM Effector VdCR Stabilises the Susceptibility Factor GhAGP31 to Suppress Host Vascular Immunity and Promote Cotton Verticillium Wilt

Plant, Cell &Environment, EarlyView.
ABSTRACT Plant pathogenic fungi secrete a wide array of effector proteins to manipulate host immunity, including those containing CFEM (Common in Fungal Extracellular Membranes) domains. Here, we identified a CFEM domain‐containing effector VdCR from Verticillium dahliae, the causal agent of cotton Verticillium wilt.
Bo Pu, Haonan Yu, Zheyu Pan, Lisheng Duan, Tao Liu, Haiyuan Li, Jiali Liu, Renfu Zhang, Xiaoping Hu, Jun Qin   +9 more
wiley   +1 more source

Role of HTLV-1 orf-I encoded proteins in viral transmission and persistence

Retrovirology, 2019
The human T cell leukemia virus type 1 (HTVL-1), first reported in 1980 by Robert Gallo’s group, is the etiologic agent of both cancer and inflammatory diseases.
Sarkis Sarkis, Veronica Galli, Ramona Moles, David Yurick, Georges Khoury, Damian F. J. Purcell, Genoveffa Franchini, Cynthia A. Pise-Masison   +7 more
doaj   +1 more source

BvCaM7 Participates in Sugar Beet (Beta vulgaris L.) Resistance to CLS (Cercospora Leaf Spot) by Activating BvPAL via BvMYB108 and Is Accompanied by Calcium Dynamics

Plant, Cell &Environment, EarlyView.
ABSTRACT CLS (Cercospora leaf spot) is a major constraint in sugar beet (Beta vulgaris L.) cultivation, yet the functions of CaM/CML family members in CLS resistance are unclear. This study identified the CaM/CML family in sugar beet and focused on BvCaM7, which was significantly upregulated under CLS. Calcium measurements revealed differential calcium
Meilin He, Hongyong Lou, Guangzhou Ding, Chunlei Zhao   +3 more
wiley   +1 more source

Understanding extracellular vesicles in antiaging

Periodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

Answer: Orf virus infection [PDF]

Annals of Saudi Medicine, 2020
Monica Garcia-Arpa, Lucia Gonzalez-Ruiz, Luis Gomez-Sanchez, Marcos Carmona-Rodriguez   +3 more
openaire   +1 more source