Results 81 to 90 of about 104,420 (304)

BLASTP hits against the NR database for all putative ORFs.

, 2014
All hits for the putative ORFs listed in Table 1 are grouped into 8 cases according to the queried ORFs and hits returned from the database.BLASTP hits against the NR database for all putative ORFs.
Yu-Nong Gong (133849), Shin-Ru Shih (110819), Chi-Jene Chen (675268), Rei-Lin Kuo (409064), Guang-Wu Chen (133840)   +4 more
core   +1 more source

Rational Design of Broad‐Spectrum Anti‐Enteroviral Molecular Glues Targeting Enteroviral RNAi Suppressors

Advanced Science, EarlyView.
By leveraging this homodimerization mechanism, molecular glues were rationally designed to induce dysfunctional 3A dimerization, thereby restoring antiviral RNAi. The optimal molecular glue, VTP‐32, demonstrated potent and pan‐enterovirus (groups A, B, D) antiviral effects.
Yuan Fang, Xiong Xie, Huidi Fan, Botao Wu, An Wang, Wenhao Dai, Zezhong Liu, Jian Li, Huoyan Tong, Jianan Li, Yujie Ren, Jinlin Wang, Xi Zhou, Hong Liu   +13 more
wiley   +1 more source

ORFs and genes that changed after modification.

, 2013
ORFs and genes that changed after modification.
Martin C. Frith (45567), Kiyoshi Asai (92186), Edward Wijaya (275834), Paul Horton (275835)   +3 more
core   +1 more source

ZDHHC18‐Mediated Palmitoylation of ORF3a Promotes SARS‐CoV‐2 Pathogenesis by Antagonizing TRIM16‐Mediated Ubiquitination and Proteasomal Degradation

Advanced Science, EarlyView.
Palmitoylation by ZDHHC18 blocks ORF3a K27‐linked ubiquitination mediated by TRIM16, thereby preventing its proteasomal degradation and strengthening viral pathogenesis. Targeting palmitoylation through a pharmacological inhibitor (2‐BP), a competitive inhibitory peptide (OPIP), or adenovirus‐mediated knockdown of ZDHHC18 expression presents a ...
Sidi Yang, Kun Li, Lihong Liu, Linsen Zeng, Qifeng Deng, Jiacheng Huang, Xiaoran Dong, Xin Wang, Jianwei Liang, Hongchao Liu, Hong Peng, Yuxin Lin, Xiaolu Xie, Yuzhen Ye, Tiefeng Xu, Zhaohuan Wang, Chun‐Mei Li, Deyin Guo   +17 more
wiley   +1 more source

Spontaneous Deletion of an "ORFanage" Region Facilitates Host Adaptation in a "Photosynthetic" Cyanophage.

PLoS ONE, 2015
Viruses have been suggested to be the largest source of genetic diversity on Earth. Genome sequencing and metagenomic surveys reveal that novel genes with unknown functions are abundant in viral genomes.
Richard J Puxty, Blanca Perez-Sepulveda, Branko Rihtman, David J Evans, Andrew D Millard, David J Scanlan   +5 more
doaj   +1 more source

RNA-seq validation for ORFs newly identified by SILAC.

, 2013
ORFs detected by SILAC-based MS were compared to deep sequencing data (RNA-seq). (A–H) Integrated Genome Browser (Affymetrix) screenshots depict gene loci with nucleotide positions referring to the plus-strand.
Marcus Krüger (277353), Bork A. Berghoff (424746), Konrad U. Förstner (413040), Anne Konzer (424747), Tom Rische (424749), Nils N. Mank (424748), Mario Looso (402639), Gabriele Klug (147020)   +7 more
core   +1 more source

Noncanonical ORFs possibly detected in mass spectrometry data.

, 2023
Noncanonical ORFs possibly detected in mass spectrometry data.
Anne-Ruxandra Carvunis (149561), Aaron Wacholder (8460039)   +1 more
core   +1 more source

DMS‐MaPseq and DREEM Analyses Implicate the Critical Role of RNA Structural Dynamics in Turnip Yellow Mosaic Virus Pathogenicity

Advanced Science, EarlyView.
RNA structural profiling of Turnip Yellow Mosaic Virus by DMS‐MaPseq and DREEM analyses uncover that viral genome‐wide RSS is highly complicated and heterogeneous, with alternative RSSs widely distributed across the genome. Notably, the viral 3’ tRNA‐like structure adopts alternative conformations in vivo.
Jiaying Zhu, Changhao Li, Chisimbily Onyia, Xindi Li, Xingxing Yan, Songxiao Zhong, Taerin Oh, Xiuren Zhang   +7 more
wiley   +1 more source

Predicted ORFs for the R40 transcripts

, 2014
Predicted ORFs for the R40 transcripts.
Stevenson, Sean, Cuming, Andrew C., Pierre-François Perroud (3317985), Aikaterini Symeonidi (3317988), Symeonidi, Aikaterini, Stuart F. McDaniel (3273798), McDaniel, Stuart F., Szövényi, Péter, Perroud, Pierre-François, Quatrano, Ralph S., Péter Szövényi (67024), Ralph S. Quatrano (3317982), Stefan A. Rensing (22608), Sean Stevenson (3317979), Andrew C. Cuming (12357), Rensing, Stefan A.   +15 more
core   +1 more source

Mn‐Induced Support Stabilization and Ir Electronic Activation Enable Acid‐Stable, Low‐Loading IrO2 Water Oxidation

Advanced Science, EarlyView.
This study introduces a dual‐regulation strategy utilizing a Mn‐doped Co3O4 support to enhance the activity and stability of low‐loading IrO2 catalysts for acidic water oxidation. Mn induces strong Mn─O covalency to reinforce the spinel lattice and activates Ir sites via interfacial electron transfer.
Zhe Liu, Guoxin Ma, Shixiang Yu, Rui Jin, Fei Wang, Xinxin Wen, Mengxin Chen, Yani Ding, Jia Liu, Xinkai Guo, Diab Khalafallah, Hassan Fouad, Xiao Ren, Siwei Li   +13 more
wiley   +1 more source