Results 101 to 110 of about 61,131 (327)
A primary neural cell culture model to study neuron, astrocyte, and microglia interactions in neuroinflammation. [PDF]
, 2020 BackgroundInteractions between neurons, astrocytes, and microglia critically influence neuroinflammatory responses to insult in the central nervous system.
Goshi, Noah +3 more
core
Magnetically levitated mesenchymal stem cell spheroids cultured with a collagen gel maintain phenotype and quiescence [PDF]
, 2017 Multicellular spheroids are an established system for three-dimensional cell culture. Spheroids are typically generated using hanging drop or non-adherent culture; however, an emerging technique is to use magnetic levitation.
Berry, Catherine C. +5 more
core +2 more sources
Lab on a Chip, 2020 Traditional drug screening models are often unable to faithfully recapitulate human physiology in health and disease, motivating the development of microfluidic organs-on-a-chip (OOC) platforms that can mimic many aspects of human physiology and in the ...
Alan Chramiec +13 more
semanticscholar +1 more source
Organ-on-a-chip for assessing environmental toxicants [PDF]
Current Opinion in Biotechnology, 2017 Man-made xenobiotics, whose potential toxicological effects are not fully understood, are oversaturating the already-contaminated environment. Due to the rate of toxicant accumulation, unmanaged disposal, and unknown adverse effects to the environment and the human population, there is a crucial need to screen for environmental toxicants. Animal models
Soohee, Cho, Jeong-Yeol, Yoon
openaire +2 more sources
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Lab on a Chip, 2020 The outer blood-retinal barrier (oBRB) tightly controls the transport processes between the neural tissue of the retina and the underlying blood vessel network.
Yusuf B Arık +13 more
semanticscholar +1 more source
Engineering cell heterogeneity into organs-on-a-chip [PDF]
Lab on a Chip, 2018 To improve predictive efficacy of organ-on-a-chip devices, developers must consider cell heterogeneity.
David R. Mertz +2 more
openaire +2 more sources
Arthritis Care &Research, Accepted Article.Objectives There is growing interest in evaluating new strategies to delay or prevent post‐traumatic osteoarthritis (PTOA) in individuals who have sustained anterior cruciate ligament (ACL) injury. This study sought to determine characteristics of potential treatments that are acceptable to patients with ACL injury.
Kevin Kennedy +9 more
wiley +1 more source
New Methods in Tissue Engineering: Improved Models for Viral Infection [PDF]
, 2014 New insights in the study of virus and host biology in the context of viral infection are made possible by the development of model systems that faithfully recapitulate the in vivo viral life cycle.
Bhatia, Sangeeta N +4 more
core +1 more source
Scientific ReportsSnakebite envenomation is a major public health issue which causes severe morbidity and mortality, affecting millions of people annually. Of a diverse range of clinical manifestations, local and systemic haemorrhage are of particular relevance, as this ...
Mátyás A. Bittenbinder +5 more
semanticscholar +1 more source