Results 111 to 120 of about 91,588,802 (303)

Organisms-on-a-chip

open access: yesEPJ Web of Conferences
The progression of fibrosis is frequently related to a failed healing process, and it may affect many tissues and organs causing severe consequences including post-infarct heart insufficiency, post-injury limb paralysis, cirrhosis, nephropathy, retinopathy, failure of implanted devices and even resistance to chemotherapy in solid tumours.
openaire   +2 more sources

Glucose Deprivation‐Driven Concurrent Induction of Apoptosis/Disulfidptosis/Ferroptosis by Tumor Targeting Nanoassemblies in Triple‐Negative Breast Cancer Therapy

open access: yesAdvanced Functional Materials, EarlyView.
Innovative hybrid nanoassemblies installed with ferrocene, D‐α‐tocopherol succinate, and phloretin exploit the metabolic vulnerability of triple‐negative breast cancer under glucose starvation. By blocking glucose uptake, this single nanoplatform simultaneously orchestrates apoptosis, disulfidptosis, and ferroptosis to achieve synergistic and ...
Song Yi Lee   +10 more
wiley   +1 more source

In situ differentiation and generation of functional liver organoids from human iPSCs in a 3D perfusable chip system [PDF]

open access: yes, 2018
Liver organoids derived from human pluripotent stem cells (PSCs) represent a new type of in vitro liver model for understanding organ development, disease mechanism and drug testing.
Qin, Jianhua   +6 more
core   +1 more source

Engineering Solutions for Representative Models of the Gastrointestinal Human-Microbe Interface

open access: yesEngineering, 2017
Host-microbe interactions at the gastrointestinal interface have emerged as a key component in the governance of human health and disease. Advances in micro-physiological systems are providing researchers with unprecedented access and insights into this ...
Marc Mac Giolla Eain   +5 more
doaj   +1 more source

Synthesis of AgBiS2 and AgInS2 Based on Formation Energies in Sulfur‐Rich Reducing Flame

open access: yesAdvanced Functional Materials, EarlyView.
High‐surface‐area AgInS2 and AgBiS2 nanoparticles were synthesized via enclosed flame spray pyrolysis by tuning flame conditions and formation energies to guide phase formation. Flame parameters were tuned to suppress oxides and enable pure sulfide phase growth.
Muhammad Ali Martuza   +7 more
wiley   +1 more source

Bioprinted 3-dimensional lung organoids for respiratory disease modeling and therapeutic applications [PDF]

open access: yesOrganoid
Advances in 3-dimensional (3D) lung models have created new opportunities in respiratory research, providing alternatives to conventional 2-dimensional cultures and animal models.
Jimin Jang, Se-Ran Yang
doaj   +1 more source

An In Situ Oxidation Strategy for Ti3C2@TiO2 Heterojunction: Narrow‐Band Photodetection and Trace Chromium Ion Determination

open access: yesAdvanced Functional Materials, EarlyView.
A Ti3C2@TiO2 heterostructure has been successfully fabricated by an in situ oxidation approach. The as‐fabricated Ti3C2@TiO2‐based photodetector exhibits narrow‐spectrum response with excellent stability. It also realizes sensitive Cr(VI) detection in a large concentration range of 10−12–10−6 M with an ultra‐low detection limit of 7.6 × 10−12 M ...
Jiahui Hou   +11 more
wiley   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

open access: yesAdvanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami   +4 more
wiley   +1 more source

Organ-on-a-chip : engineered microenvironments for safety and efficacy testing / [PDF]

open access: yes
Includes index.Print version record.Includes bibliographical references and index ...
Peitsch, Manuel Claude,editor.   +2 more
core  

Modelling cardiac fibrosis through a mechanically active multi-chamber organ on chip device [PDF]

open access: yes, 2020
Introduction Cardiac fibrosis (CF) is a pathological remodeling occurring, for instance, after myocardial infarction. The process is characterized by reduction in the number of cardiomyocytes (CMs), which are substituted by proliferating fibroblasts ...
Andrea Mainardi   +8 more
core  

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