Results 101 to 110 of about 62,519 (299)

Oxygen levels in thermoplastic microfluidic devices during cell culture [PDF]

, 2013
We developed a computational model to predict oxygen levels in microfluidic plastic devices during cell culture. This model is based on experimental evaluation of oxygen levels.
Kamm, Roger Dale, Kasuya, Junichi, Ochs, Christopher J., Pavesi, Andrea   +3 more
core   +1 more source

Small Force, Big Impact: Next Generation Organ-on-a-Chip Systems Incorporating Biomechanical Cues

Frontiers in Physiology, 2018
Mechanobiology-on-a-chip is a growing field focusing on how mechanical inputs modulate physico-chemical output in microphysiological systems. It is well known that biomechanical cues trigger a variety of molecular events and adjustment of mechanical ...
Ece Ergir, Ece Ergir, Barbara Bachmann, Barbara Bachmann, Barbara Bachmann, Barbara Bachmann, Heinz Redl, Heinz Redl, Heinz Redl, Giancarlo Forte, Giancarlo Forte, Giancarlo Forte, Peter Ertl, Peter Ertl, Peter Ertl   +14 more
doaj   +1 more source

Triplet‐Triplet Annihilation Enhances Photochemical Curing Contrast for Vat‐Based 3D Printing

Advanced Functional Materials, EarlyView.
Triplet–triplet annihilation photopolymerization (TTAP) resins enhance curing contrast for digital light processing (DLP) 3D printing compared to conventional Type I and II photopolymerizations at matched optical densities. By exploiting a superlinear initiation response, TTAP preserves fine details, allowing reliable fabrication of complex structures ...
Connor J. O'Dea, Evan P. Scruggs, Zachariah A. Page   +2 more
wiley   +1 more source

Organisms-on-a-chip

EPJ Web of Conferences
The progression of fibrosis is frequently related to a failed healing process, and it may affect many tissues and organs causing severe consequences including post-infarct heart insufficiency, post-injury limb paralysis, cirrhosis, nephropathy, retinopathy, failure of implanted devices and even resistance to chemotherapy in solid tumours.
openaire   +2 more sources

Parallel 3D Bioprinting on SLIPS‐Microarrays

Advanced Functional Materials, EarlyView.
This work introduces the first truly parallel 3D bioprinting method, enabling both the simultaneous fabrication of hundreds of cell laden hydrogel 3D structures and their HTS in individual liquid compartments. By integrating Digital Light Processing (DLP) stereolithography with functional micropatterns, the platform decouples printing time from array ...
Julius von Padberg, Julian A. Serna, Maike Schliephake, Pavel A. Levkin   +3 more
wiley   +1 more source

Differentiation, Evaluation, and Application of Human Induced Pluripotent Stem Cell–Derived Endothelial Cells [PDF]

, 2017
The emergence of induced pluripotent stem cell (iPSC) technology paves the way to generate large numbers of patient-specific endothelial cells (ECs) that can be potentially delivered for regenerative medicine in patients with cardiovascular disease.
Gil, Chang-Hyun, Lin, Yang, Yoder, Mervin C.   +2 more
core   +1 more source

Organ-on-a-chip: a more promising in vitro model [PDF]

Jichu yixue yu linchuang
Traditional in vitro models have inevitable limitations and there are significant differences in assessing drug efficacy and side effects as compared to human trials.
YANG Zhenli, XIA Yujia, LIU Yuqin
doaj   +1 more source

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

Advanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo, Mi Jeong Lee, Hyun Wook Kang, Seonhee Byeon, Soo‐Kyoung Choi, Nakwon Choi, Seung‐Woo Cho, Yoonhee Jin   +7 more
wiley   +1 more source

A primary neural cell culture model to study neuron, astrocyte, and microglia interactions in neuroinflammation. [PDF]

, 2020
BackgroundInteractions between neurons, astrocytes, and microglia critically influence neuroinflammatory responses to insult in the central nervous system.
Goshi, Noah, Lein, Pamela J, Morgan, Rhianna K, Seker, Erkin   +3 more
core  

Magnetically levitated mesenchymal stem cell spheroids cultured with a collagen gel maintain phenotype and quiescence [PDF]

, 2017
Multicellular spheroids are an established system for three-dimensional cell culture. Spheroids are typically generated using hanging drop or non-adherent culture; however, an emerging technique is to use magnetic levitation.
Berry, Catherine C., Dalby, Matthew J., Lewis, Emily E.L., Lewis, Natasha S., Mullin, Margaret, Wheadon, Helen   +5 more
core   +2 more sources