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Comprehensive Development in Organ-On-A-Chip Technology
Journal of Pharmaceutical Sciences, 2022The expeditious advancement in the organ on chip technology provided a phase change to the conventional in vitro tests used to evaluate absorption, distribution, metabolism, excretion (ADME) studies and toxicity assessments. The demand for an accurate predictive model for assessing toxicity and reducing the potential risk factors became the prime area ...
X, Joseph +3 more
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Organs-on-a-chip for drug discovery
Current Opinion in Pharmacology, 2013The current drug discovery process is arduous and costly, and a majority of the drug candidates entering clinical trials fail to make it to the marketplace. The standard static well culture approaches, although useful, do not fully capture the intricate in vivo environment.
Seila, Selimović +2 more
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2017
Organ-on-a-chip systems are novel platforms, which imitate key functions of living organ, including specific microarchitectures, cell–cell and tissue–tissue interactions, and extracellular communication. Microtechnology offers the possibility of creating more complex, multi-organ platforms known as Body-on-a-chip or Human-on-a-chip.
Aleksandra Szuplewska +2 more
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Organ-on-a-chip systems are novel platforms, which imitate key functions of living organ, including specific microarchitectures, cell–cell and tissue–tissue interactions, and extracellular communication. Microtechnology offers the possibility of creating more complex, multi-organ platforms known as Body-on-a-chip or Human-on-a-chip.
Aleksandra Szuplewska +2 more
openaire +1 more source
2022
This presentation was uploaded for the SGS Research Showcase 2022. Choose your favourite presentation for the SGS Research Showcase People's Choice Award: Pecha Kucha category.
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This presentation was uploaded for the SGS Research Showcase 2022. Choose your favourite presentation for the SGS Research Showcase People's Choice Award: Pecha Kucha category.
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Emerging Biosensor Trends in Organ-on-a-Chip
2020Organ-on-a-chip technology is ideally suited to cultivate and analyze 2D/3D cell cultures, organoids, and other tissue analogues in vitro, because these microphysiological systems have been shown to generate architectures, structural organization, and functions that closely resemble their respective human tissues and organs. Although great efforts have
Mario, Rothbauer, Peter, Ertl
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A guide to the organ-on-a-chip
Nature Reviews Methods Primers, 2022Chak Ming Leung, Pim de Haan, Ge-Ah Kim
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Clamping strategies for organ-on-a-chip devices
Nature Reviews Materials, 2023Lorenzo Moroni, Stefan Giselbrecht
exaly