Results 221 to 230 of about 61,131 (327)

A Human‐Based Skin‐Lymphoreticular Model‐on‐Chip to Emulate Inflammatory Skin Conditions

Advanced Healthcare Materials, EarlyView.
A human‐based lymphoreticular (LR) model was developed through guided self‐assembly and integrated in a skin‐lymphoreticular co‐culture in a microfluidic organ‐on‐chip to mimic interactions between skin and its draining lymph nodes. The human‐based skin‐lymphoreticular model resembles a minimally functional unit that allows to study interactions ...
Zheng Tan, Partho Protim Adhikary, Dana Wörz, Sarah Hedtrich   +3 more
wiley   +1 more source

Organ-on-a-Chip Models of the Female Reproductive System: Current Progress and Future Perspectives. [PDF]

Micromachines (Basel)
Pan M, Chen H, Deng K, Xiao K.
europepmc   +1 more source

Microphysiological Systems of Lymphatics and Immune Organs

Advanced Healthcare Materials, EarlyView.
This review surveys recent progress in engineering lymphatic microenvironments and immune organoids within microphysiological systems, emphasizing innovative strategies to recreate the biochemical and biophysical complexity of native lymphatic tissues.
Ishita Jain, Ankur Singh, Andrés J. García   +2 more
wiley   +1 more source

Editorial: Latest advancements in organ-on-a-chip technology. [PDF]

Front Pharmacol
Kassis J, Wan Z.
europepmc   +1 more source

Preliminary Study of a Ninj1‐Loaded Bimodal Ultrasound/NIR Fluorescence Targeted Molecular Probe for Diagnosing Early‐Stage Inflammation in Coronary Microvascular Dysfunction

Advanced Healthcare Materials, EarlyView.
Coronary microvascular dysfunction (CMD) targeting remains a challenge for precise diagnosis. This work presents a dual‐modal nanoprobe (T‐IR780‐NBs) that combines ultrasound contrast with near‐infrared fluorescence. This technology utilizes proteomics‐derived antibodies that specifically localize to inflamed and injured cardiac tissue, enabling ...
Xiaohui Xu, Lina Guan, Baihetiya Tayier, Chen Yuan, Shangke Chen, Qi Shi, Yuming Mu   +6 more
wiley   +1 more source

Integrative bioengineering strategies for endometrial regeneration: From biomaterials and stem cells to organoids and organ-on-a-chip technologies. [PDF]

Theranostics
Kim SR, Lee HY.
europepmc   +1 more source

Doxorubicin‐Loaded Metal–Organic Framework for Ferroptosis‐Enhanced Chemotherapy Through Sustained Zn Release and Glutathione Peroxidase Downregulation

Advanced Healthcare Materials, EarlyView.
A robust zinc‐based metal–organic framework (ZnMOF) enables dual functions of doxorubicin delivery and sustained Zn2+ release to trigger ferroptosis‐enhnaced chemotherapy. DOX@ZnMOF effectively depletes intracellular glutathione, suppresses GPX4, and elevates reactive oxygen species, leading to efficient oxidative DNA damage and apoptosis.
Xin Ma, Chenghua Deng, Chaoyu Wang, Langston Tilman, Jinhong Li, Wenbin Lin   +5 more
wiley   +1 more source

Low-cost injection moulding strategies for the fabrication of organ on a chip devices [PDF]

Charmet, Jérôme, Couling, Kevin, Dallmann, Robert, Goodship, Vannessa, Middleton, Bethany J.   +4 more
core  

A microfluidic cell culture device with integrated microelectrodes for barrier studies. [PDF]

, 2016
Andresen, Thomas Lars, Dufva, Martin, Kutter, Jörg P., Tan, Hsih-Yin   +3 more
core   +1 more source

Modeling of lung-liver interaction during infection in a human fluidic organ-on-a-chip. [PDF]

Sci Rep
Reinhold S, Herr C, Yao Y, Pourrostami M, Ritzmann F, Lehr T, Selzer D, Kohl Y, Yildiz D, Slevogt H, Beisswenger C, Bals R.   +11 more
europepmc   +1 more source