Results 241 to 250 of about 61,131 (327)

Innovative organ-on-a-chip platforms for exploring tumorigenesis and therapy in head and neck cancer. [PDF]

J Transl Med
Lin C, Zhang Z, Yang F, Gu S, Zuo J, Wu Y, Zhang J, Zhou T, Zhang Y, Chen Z, Gu Z, Shen Z.   +11 more
europepmc   +1 more source

Skin‐Interfaced Therapeutic Patches for Wound Fluid Management and Transdermal Drug Delivery

Advanced Healthcare Materials, EarlyView.
This study presents an integrated skin‐interfaced device combining microfluidics, hydrogel film technology, flexible electronics, and iontophoresis‐based transdermal delivery of PDRN to enhance wound healing. The device effectively manages wound fluid, maintains optimal moisture, and non‐invasively delivers therapeutic drugs.
Dongjun Han, Donghyun Kim, Haram Lee, Dong‐Wook Park, Sung Soo Kwak, Joohee Kim   +5 more
wiley   +1 more source

Bridging the Gap: How Organ-on-a-Chip Technology Facilitates the Battle against Glioma. [PDF]

Small Sci
Liu S, Gong Z, Zhou D, Ayala-Nunez V, Xu T, Wick P.   +5 more
europepmc   +1 more source

A multi-throughput multi-organ-on-a-chip system on a plate formatted pneumatic pressure-driven medium circulation platform.

Lab on a Chip, 2017
T. Satoh, S. Sugiura, Shin Kazumi, Reiko Onuki-Nagasaki, S. Ishida, K. Kikuchi, M. Kakiki, Toshiyuki Kanamori   +7 more
semanticscholar   +1 more source

Bone Healing Around Implants in Normal and Medically Compromised Conditions: Osteoporosis and Diabetes

Advanced Healthcare Materials, EarlyView.
xx xx. ABSTRACT Osseointegration of orthopedic and dental implants is influenced by local and systemic factors, including their physicochemical surface properties and the patient's overall health status. Titanium and its alloys have been a longstanding standard for bone implants due to their innate biocompatibility and mechanical properties.
Dainelys Guadarrama Bello, Fabio Variola, Antonio Nanci   +2 more
wiley   +1 more source

An Organ-on-a-Chip Modular Platform with Integrated Immunobiosensors for Monitoring the Extracellular Environment. [PDF]

Micromachines (Basel)
Kanioura A, Filippidou MK, Tsounidi D, Petrou PS, Chatzandroulis S, Tserepi A.   +5 more
europepmc   +1 more source

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

Advanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney, Silvia M. Mihăilă, Lorenzo Moroni, Carlos Mota   +3 more
wiley   +1 more source

Porcine intestinal organoids cultured in an organ-on-a-chip microphysiological system. [PDF]

Biochem Biophys Rep
Bacon J, Kitchel H, Stutz J, Chen JH, Smith A, Van Horn RD, Moreland C, Abraham T, Baker T, Aihara E, Hillgren K.   +10 more
europepmc   +1 more source

A Synovium‐on‐Chip Platform to Study Multicellular Interactions in Arthritis

Advanced Healthcare Materials, EarlyView.
The Synovium‐on‐Chip comprises a thin microporous PDMS membrane to support co‐culture of fibroblast‐like synoviocytes (FLS), THP‐1‐derived macrophages, and endothelial cells, enabling real‐time analysis of synovial‐vascular interactions. FLS migration through the pores drives endothelial remodeling, while TNF‐α stimulation induces robust inflammatory ...
Laurens R. Spoelstra, Fleur R. Semmekrot, Nuno Araújo‐Gomes, Daniël Wijnperle, Monique M. A. Helsen, Martijn H.J. Van Den Bosch, Loes. I. Segerink, Séverine Le Gac, Marcel Karperien   +8 more
wiley   +1 more source

Organoid, organ-on-a-chip and traditional Chinese medicine. [PDF]

Chin Med
Yang J, Jiang Y, Li M, Wu K, Wei S, Zhao Y, Shen J, Du F, Chen Y, Deng S, Xiao Z, Yuan W, Wu X.   +12 more
europepmc   +1 more source