Results 81 to 90 of about 61,131 (327)

Correction: Organ-on-a-chip with integrated semitransparent organic electrodes for barrier function monitoring.

Lab on a Chip, 2023
Correction for 'Organ-on-a-chip with integrated semitransparent organic electrodes for barrier function monitoring' by Denise Marrero et al., Lab Chip, 2023, https://doi.org/10.1039/d2lc01097f.
Denise Marrero, A. Guimerà, L. Maes, R. Villa, Mar Alvarez, X. Illa   +5 more
semanticscholar   +1 more source

Integrating biological vasculature into a multi-organ-chip microsystem [PDF]

, 2013
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG geförderten) Allianz- bzw. Nationallizenz frei zugänglich.This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence
Brincker, Sven, Busek, Mathias, Groth, Benjamin, Hoffmann, Silke, Horland, Reyk, Lauster, Roland, Lindner, Gerd, Lorenz, Alexandra, Marx, Uwe, Menzel, Ulrike, Schimek, Katharina, Sonntag, Frank, Walles, Heike   +12 more
core   +2 more sources

Kidney, Organ on a Chip drug.pdf

, 2022
Current Status of Kidney Organ-On-A-ChipTechnology for Safe Evaluation of Drug ...
Ramos Guevara, Michelle Adriana, Chapa, Christian   +1 more
openaire   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Cancer Cell Drug Response Transcriptomes in 3D [PDF]

, 2016
The relevance of different in vitro culture models of cancer cells is a hot topic, but few systematic and definitive analyses in this area exist. In this issue of Cell Chemical Biology, Senkowski et al.
Wennerberg, Krister
core   +1 more source

A novel approach to interrogating the effects of chemical warfare agent exposure using organ-on-a-chip technology and multiomic analysis

PLoS ONE, 2023
Organ-on-a-chip platforms are utilized in global bioanalytical and toxicological studies as a way to reduce materials and increase throughput as compared to in vivo based experiments.
Tyler D. P. Goralski, Conor C. Jenkins, Daniel J. Angelini, J. Horsmon, Elizabeth S. Dhummakupt, Gabrielle M. Rizzo, Brooke L. Simmons, Alvin T. Liem, Pierce A. Roth, Mark A. Karavis, Jessica M. Hill, J. Sekowski, Kyle P. Glover   +12 more
semanticscholar   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Microfluidic Organ‐on‐a‐Chip Technology for Advancement of Drug Development and Toxicology [PDF]

, 2015
In recent years, the exploitation of phenomena surrounding microfluidics has seen an increase in popularity, as researchers have found a way to use their unique properties to create superior design alternatives.
Acar, Agarwal, Annabi, Au, Augustsson, Bai, Baker, Bale, Baudoin, Baudoin, Bersini, Bhushan, Booth, Borenstein, Bricks, Chen, Chen, Cheng, Chiriaco, Condorelli, Cukierman, de Kanter, Deanfield, Douville, Dube, El-Ali, Esch, Esch, Fagerholm, Ferrell, Frey, Frohlich, Frohlich, Giridharan, Gong, Griep, Grosberg, Grosberg, Guguen-Guillouzo, Hashemi, Hashemi, Hashemi, Hattersley, He, Hinderer, Hoerstrup, Hoganson, Huang, Huang, Huang, Huh, Huh, Huh, Imura, Iori, Jang, Jang, Jang, Jeon, Jeon, Kamande, Kaplowitz, Khan, Kim, Kim, Kim, Kim, Kim, Kim, Kimura, Kirby, Kniazeva, Lee, Lee, Li, Li, Li, Li, Liu, Mahler, Marx, Marze, McCain, Meng, Mol, Moraes, Moraes, Morimoto, Mu, Nakao, Neuzil, Nichols, Odijk, Ould-Dris, Owaki, Prabhakarpandian, Ramello, Ren, Rigat-Brugarolas, Schimek, Schober, Schutte, Sechi, Shibata, Shintu, Siyan, Snouber, Song, Sreenivasan, Srigunapalan, Stucki, Sung, Sung, Sung, Sung, Sung, Suwanpayak, Tanaka, Tavana, Toh, Torisawa, Tourovskaia, van Midwoud, van Vlimmeren, Wagner, Wang, Wang, Weymann, Wikswo, Xu, Yeon, Yeon, Zhang, Zhang   +133 more
core   +3 more sources

A Comprehensive Review of Organ-on-a-Chip Technology and Its Applications

Biosensors
Organ-on-a-chip (OOC) is an emerging technology that simulates an artificial organ within a microfluidic cell culture chip. Current cell biology research focuses on in vitro cell cultures due to various limitations of in vivo testing.
Negar Farhang Doost, Soumya K. Srivastava   +1 more
doaj   +1 more source

A Fast Alternative to Soft Lithography for the Fabrication of Organ‐on‐a‐Chip Elastomeric‐Based Devices and Microactuators

Advancement of science, 2021
Organ‐on‐a‐chip technology promises to revolutionize how pre‐clinical human trials are conducted. Engineering an in vitro environment that mimics the functionality and architecture of human physiology is essential toward building better platforms for ...
D. Ferreira, M. Rothbauer, J. Conde, P. Ertl, Carla Oliveira, P. Granja   +5 more
semanticscholar   +1 more source