Organ-on-chip - Open Access .click

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Organs-on-chips: research and commercial perspectives

Drug Discovery Today, 2017
Traditional preclinical drug testing methods utilize animal models to predict pharmacology and toxicology profiles. However, the data obtained from such methods cannot be directly extrapolated to humans and often do not provide a safe starting dose for first-in-human studies.
Aarathi, Balijepalli, Vaibhav, Sivaramakrishan +1 more
openaire +2 more sources

Engineering human islet organoids from iPSCs using an organ-on-chip platform.

Lab on a Chip, 2019
Human pluripotent stem cell (hPSC)-derived islet cells provide promising resources for diabetes studies, cell replacement treatment and drug screening.
Tingting Tao +7 more
semanticscholar +1 more source

Bioinspired Engineering of Organ-on-Chip Devices

2019
The human body can be viewed as an organism consisting of a variety of cellular and non-cellular materials interacting in a highly ordered manner. Its complex and hierarchical nature inspires the multi-level recapitulation of the human body in order to gain insights into the inner workings of life.
Li, Wang, Zhongyu, Li, Cong, Xu, Jianhua, Qin +3 more
openaire +2 more sources

Developing organs-on-chips for biomedicine