Results 101 to 110 of about 801,709 (375)
APL Bioengineering, 2020 Organ-on-a-chip (OoC) systems have evolved to a promising alternative to animal testing and traditional cell assays in drug development and enable personalization for precision medicine.
Stefan Schneider +4 more
doaj +1 more source
Pharmacological activation of endogenous protective pathways against oxidative stress under conditions of sepsis [PDF]
, 2016 Funding The study was funded entirely by institutional funds.Peer ...
Galley, H. F. +4 more
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Polymerase Chain Reaction and blood culture for diagnosis of canine sepsis
Ciência Rural, 2018 : Sepsis is characterized by the presence of organ dysfunction secondary to the dysregulated systemic inflammatory response associated with an infection, and has high mortality rates.
Marcelo Marques da Silveira +8 more
doaj +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
A Brief History of Cell Culture: From Harrison to Organs-on-a-Chip
CellsThis comprehensive overview of the historical milestones in cell culture underscores key breakthroughs that have shaped the field over time. It begins with Wilhelm Roux’s seminal experiments in the 1880s, followed by the pioneering efforts of Ross ...
Lincoln Gozzi Moro +8 more
doaj +1 more source
Detection of Brucella organisms from Egyptian raw milk using cultural and molecular techniques
Kafrelsheikh Veterinary Medical Journal, 2020 Aim: This study aimed to detect Brucella organisms in Egyptian raw milk using cultural and molecular techniques.Methods: Two hundred bulk milk samples were collected from 2 cities at El-Gharbia and Kafer El-Sheikh Governorates during the summer and winter seasons.
Ibrahim Aman +3 more
openaire +1 more source
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Current ecological understanding of fungal-like pathogens of fish: what lies beneath? [PDF]
, 2014 Despite increasingly sophisticated microbiological techniques, and long after the first discovery of microbes, basic knowledge is still lacking to fully appreciate the ecological importance of microbial parasites in fish. This is likely due to the nature
Casey eJessop +6 more
core +4 more sources
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source