Results 71 to 80 of about 790,004 (346)

Pop stars and idolatry: an investigation of the worship of popular music icons, and the music and cult of Prince. [PDF]

, 2010
Prince is an artist who integrates elements from the sacred into his work. He uses popular iconography to present himself as an icon of consumer culture, as a deified ‘rock god’ worshipped by his fans, and as a preacher leading his audience like a ...
Baty S. Paige, Besancon Alain, Boorstin Daniel J., Buxton D., Cooper Carol, Cowan Douglas, Durkheim Emile, Frith Simon, Goodwin Andrew, Hallick Mary Paloumpis, Hill Dave, Longhurst Brian, Lowenthal Leo, Murry Charles Shaar, O’Hagan Sean, Rein Irving, Rupert Till, Salewicz Chris, Sutcliffe Phil, Till Rupert, Tosches Nick, Tudor Andrew, Vincent Rickey, White Charles   +23 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Fungal speciation using quantitative polymerase chain reaction (QPCR) in patients with and without chronic rhinosinusitis. [PDF]

, 2006
Objectives/hypothesisThe objectives of this study were to determine the mycology of the middle meatus using an endoscopically guided brush sampling technique and polymerase chain reaction laboratory processing of nasal mucous; to compare the mycology of ...
Goldberg, Andrew N, Murr, Andrew H, Vesper, Stephen   +2 more
core  

CMV in the gut: a critical review of CMV detection in the immunocompetent host with colitis. [PDF]

, 2015
As scientific techniques for the detection of cytomegalovirus (CMV) improve, we are able to detect small amounts of CMV in the mucosal wall. As clinicians, we are unsure how to interpret the results of this novel test.
Goodman, AL, Griffiths, PD, Murray, CD, Watkins, J, Webster, DP   +4 more
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Plant organ cultures as masked mycotoxin biofactories: Deciphering the fate of zearalenone in micropropagated durum wheat roots and leaves. [PDF]

PLoS ONE, 2017
"Masked mycotoxins" senso strictu are conjugates of mycotoxins resulting from metabolic pathways activated by the interplay between pathogenic fungi and infected plants.
Laura Righetti, Enrico Rolli, Gianni Galaverna, Michele Suman, Renato Bruni, Chiara Dall'Asta   +5 more
doaj   +1 more source

The Value of the Dead: The Commodification of Corpses in Western Culture [PDF]

, 2018
Since the 19th century, the deceased human body and its parts have been increasingly dehumanized, objectified, and commodified in Western culture. Thus, in a relatively short period of time, the corpse became, and continues to be, a highly valuable ...
Wallace, Charles Z.
core   +2 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Experimental liver models: From cell culture techniques to microfluidic organs‐on‐chip [PDF]

, 2021
Michela Anna Polidoro, Erika Ferrari, Simona Marzorati, Ana Lleó, Marco Rasponi   +4 more
openalex   +1 more source

Determination of antimicrobial susceptibilities on infected urines without isolation [PDF]

, 1979
A method is described for the quick determination of the susceptibilities of various unidentified bacteria contained in an aqueous physiological fluid sample, particularly urine, to one or more antibiotics.
Barza, M. J., Chappelle, E. W., Deming, J. W., Picciolo, G. L., Shrock, C. G., Vellend, H., Weinstein, L.   +6 more
core   +1 more source