Results 31 to 40 of about 37,769 (267)

Cost-effectiveness of Interventions to Increase Utilization of Kidneys From Deceased Donors With Primary Brain Malignancy in an Australian Setting

Transplantation Direct, 2023
Background. Kidneys from potential deceased donors with brain cancer are often foregone due to concerns of cancer transmission risk to recipients. There may be uncertainty around donors’ medical history and their absolute transmission risk or risk-averse
James A. Hedley, MBiostats, Patrick J. Kelly, PhD, Melanie Wyld, PhD, Karan Shah, MS, Rachael L. Morton, PhD, Juliet Byrnes, PhD, Brenda M. Rosales, PhD, Nicole L. De La Mata, PhD, Kate Wyburn, PhD, Angela C. Webster, PhD   +9 more
doaj   +1 more source

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar, Karen Thibaudeau, Mary Mathias, Heather McDaniel, Madlen Reschke, Klaus Tenbrock, Joseph M. Parker, Amy Shapiro   +7 more
wiley   +1 more source

Perfusion-induced renal hardness measured by Shore durometer: a novel, low-cost biomarker of donor kidney quality

Renal Failure
Quantitative assessment of donor kidney quality remains challenging in transplantation medicine. This study investigated the correlation between Shore durometer-measured renal hardness and established quality indicators (hypothermic machine perfusion ...
Guozhen Chen, Haiping Liu, Fan Wang, Chenguang Ding, Wujun Xue   +4 more
doaj   +1 more source

Rational Use of Herbal Products in Pediatric Patients Treated With Anticancer Drugs in the European Union

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The use of herbal medical preparation (HMP) is rising among pediatric oncology patients, often to manage treatment‐related symptoms. Their effectiveness remains uncertain, and the risk of herb–drug interactions is underestimated.
Orianne Mahot, Mathieu Corvaisier, Laurence Spiesser‐Robelet, Mylène Duplan, Isabelle Pellier, Delphine Bourneau‐Martin, Séverine Derbré   +6 more
wiley   +1 more source

Association Between Three Lung Donor Scores and Lung Acceptance in DBD and DCD Donors

Transplant International
The use of extended criteria donors (ECD) has become increasingly important in lung transplantation to address organ donor shortages. To better assess lung graft quality and optimize donor selection, several scores have been developed.
Fabian Iten, Julius Weiss, Simon Schwab, Franziska Beyeler, Thorsten Krueger, Angela Koutsokera, Macé Schuurmans, Isabelle Opitz, György Lang, Franz Immer   +9 more
doaj   +1 more source

Guidelines for Pediatric Radiotherapy Simulation: A Report From the Children's Oncology Group Radiation Oncology Discipline

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric radiation therapy presents unique challenges compared to adult treatments, including those of immobilization, potential need for sedation, and the critical importance of accurate, reproducible positioning. Additionally, heightened attention to imaging doses is necessary to minimize long‐term toxicity in survivors.
Parham Alaei, Stephen Mihalcik, Sujith Baliga, Young Kwok, Dana Casey, Eric Ehler, Christiane Burton, John C. Breneman, Daphne A. Haas‐Kogan, Suzanne L. Wolden, Arnold C. Paulino, Nadia N. Laack, Natia Esiashvili, Sarah Milgrom, Christine Hill‐Kayser, Thomas J. Fitzgerald, John A. Kalapurakal, Chia‐Ho Hua   +17 more
wiley   +1 more source

Evaluating the efficacy of basiliximab versus no induction in low-immunological-risk kidney transplant recipients: a propensity score matched analysis

Renal Failure
Background The optimal use of induction therapy in low-immunological-risk kidney transplant recipients (KTRs) remains uncertain. While Basiliximab (BSX) is widely utilized, its comparative outcomes with no induction therapy require further evaluation ...
Dahao Zhang, Jiqiu Wen, Jianhui Dong, Rong Ma, Shijian Li, Jihua Wu, Ning Wen, Zhiying Lei, Haibin Li, Jun Yin, Xuyong Sun   +10 more
doaj   +1 more source

Dysregulation of innate cell types in the hepatic immune microenvironment of alcoholic liver cirrhosis

Frontiers in Immunology, 2023
IntroductionThe risk of alcoholic cirrhosis increases in a dose- and time-dependent manner with alcohol consumption and ethanol metabolism in the liver. Currently, no effective antifibrotic therapies are available.
Ao Ren, Ao Ren, Ao Ren, Wenjing He, Wenjing He, Wenjing He, Jiawei Rao, Jiawei Rao, Jiawei Rao, Dongmei Ye, Dongmei Ye, Dongmei Ye, Pengrui Cheng, Pengrui Cheng, Pengrui Cheng, Qian Jian, Qian Jian, Qian Jian, Zongli Fu, Zongli Fu, Zongli Fu, Xuzhi Zhang, Xuzhi Zhang, Xuzhi Zhang, Ronghai Deng, Ronghai Deng, Ronghai Deng, Yifang Gao, Yifang Gao, Yifang Gao, Yi Ma, Yi Ma, Yi Ma   +32 more
doaj   +1 more source

Organ donation in Spain [PDF]

Nephrology Dialysis Transplantation, 1999
attached to the Spanish Department of Health. From Background the very beginning, it was presumed that the shortage of organs is the principal limitation to organ transplant Spain is a European Community country with 39.66 and that the problem was probably not the absence of million inhabitants divided into 17 autonomous suitable donors but a failure ...
B, Miranda, M, Fernández Lucas, C, de Felipe, M, Naya, J M, González-Posada, R, Matesanz   +5 more
openaire   +2 more sources

Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall, Emma N. Harrison, Genevieve C. Kendall   +2 more
wiley   +1 more source