Journal of the American Medical Association (JAMA), 2019 Importance Experimental data suggest that intravenous vitamin C may attenuate inflammation and vascular injury associated with sepsis and acute respiratory distress syndrome (ARDS). Objective To determine the effect of intravenous vitamin C infusion on
A. Fowler +35 more
semanticscholar +1 more source
Statin therapy in critical illness : an international survey of intensive care physicians' opinions, attitudes and practice [PDF]
, 2012 Background Pleotropic effects of statins on inflammation are hypothesised to attenuate the severity of and possibly prevent the occurrence of the host inflammatory response to pathogen and infection-related acute organ failure.
Di Gangi, Stefania +6 more
core +1 more source
Hydroxymethylglutaryl-CoA reductase inhibition with simvastatin in acute lung injury to reduce pulmonary dysfunction (HARP-2) trial : study protocol for a randomized controlled trial [PDF]
, 2012 Acute lung injury (ALI) is a common devastating clinical syndrome characterized by life-threatening respiratory failure requiring mechanical ventilation and multiple organ failure.
A Mercat +31 more
core +1 more source
Organ Failure Due to Systemic Injury in Acute Pancreatitis.
Gastroenterology, 2019 Acute pancreatitis may be associated with both local and systemic complications. Systemic injury manifests in the form of organ failure, which is seen in approximately 20% of all cases of acute pancreatitis and defines "severe acute pancreatitis." Organ ...
P. Garg, Vijay P. Singh
semanticscholar +1 more source
Circulating Biologically Active Adrenomedullin Predicts Organ Failure and Mortality in Sepsis [PDF]
, 2019 BACKGROUND: Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Biologically active adrenomedullin (bio-ADM) is an emerging biomarker for sepsis.
Bergmann, A. +4 more
core +1 more source
Rating organ failure via adverse events using data mining in the intensive care unit [PDF]
, 2008 The main intensive care unit (ICU) goal is to avoid or reverse the organ failure process by adopting a timely intervention. Within this context, early identification of organ impairment is a key issue. The sequential organ failure assessment (SOFA) is an
Cortez, Paulo +4 more
core +1 more source
Soluble toll-like receptor 2 is a biomarker for sepsis in critically ill patients with multi-organ failure within 12 h of ICU admission [PDF]
, 2017 Soluble TLR2 levels are elevated in infective and inflammatory conditions, but its diagnostic value with sepsis-induced multi-organ failure has not been evaluated.
Durno, Kimberley +6 more
core +2 more sources
Does the Presence of a Measurable Blood Alcohol Level in a Potential Organ Donor Affect the Outcome of Liver Transplantation? [PDF]
, 1991 The widespread application of hepatic transplantation has created a tremendous demand for donor organs. An assessment of donor parameters is thought to be important in selecting good donors; however, the criteria utilized have not been standardized. This
Ascher NL +9 more
core +1 more source
Hepatic artery pseudoaneurysm ligation after orthotopic liver transplantation-a report of 7 cases [PDF]
, 1992 Pseudoaneurysm (PA) is a rare but life-threatening complication of liver transplantation. The authors present their experience on 7 patients treated by ligation of a post-OLT PA.
Gordon, R +7 more
core +1 more source
In vitro effect of canine hyperimmune sera on TNFa activity [PDF]
, 2006 [Introduction]: Septic shock in dogs is caused by cardiovascular and vasomotor failure associated with an uncontrolled intrinsic release of inflammatory mediators [1–5].
Kotiw, Michael +3 more
core +2 more sources