Results 21 to 30 of about 1,172,749 (303)
Circulating adrenomedullin estimates survival and reversibility of organ failure in sepsis: the prospective observational multinational Adrenomedullin and Outcome in Sepsis and Septic Shock-1 (AdrenOSS-1) study [PDF]
, 2018 Background: Adrenomedullin (ADM) regulates vascular tone and endothelial permeability during sepsis. Levels of circulating biologically active ADM (bio-ADM) show an inverse relationship with blood pressure and a direct relationship with vasopressor ...Abroug, S., Alcourt, Y., Allam, H., Antonelli, M., Aubrey, A., Bachoumas, K., Bangert, K., Barthelemy, R., Bartoli, C., Baudrillart, L., Bayer, S., Beeken, T., Beeker, T., Begot, E., Beishuizen, A., Beishuizen, B., Berghe, C., Bergmann, A., Berquier, G., Besancenot, H., Blet, A., Bloos, F., Bloos, P., Bodet-Contentin, L., Boivin, A., Bongiovanni, C., Bonnet, F., Border, N., Bos-Burgmeijer, M., Bouadma, L., Bouhours, G., Bourdier, J., Bourzeix, P., Braad, A., Brick, L., Brulls, C., Buelens, I., Calvat, S., Caumon, E., Cayot, S., Chapellas, C., Chassier, C., Chenaf, S., Chousterman, B. G., Clere-Jehl, R., Colin, G., Collienne, C., Constantin, J. -M., Conte, M., Cornet, A., Cracco, C., Cupaciu, A., Cutuli, S. L., D'Arrigo, S., Daix, T., Damoisel, C., De Heer, G., De Schryver, N., Deiler, V., Deisz, R., Delabranche, X., Delmas, J., Denou, F., Dequin, P. F., Desachy, A., Deschamps, A., Deye, N., Dhif, N., Di Somma, S., Digravio, V., Dubief, E., Duchambon, A. -A., Dugernier, T., Dujardin, M. -F., Ehrmann, S., Fally, M. A., Fedou, A. -L., Feld, F., Feliot, E., Fesard, P., Fiancette, M., Fournier, M. -C., Francois, B., Freys, G., Frings, D., Fuhrmann, V., Fullekrug, B., Gaillard, T., Galy, A., Garcon, P., Garot, D., Gaudry, S., Gaugain, S., Gayat, E., Geukens, P., Geven, C., Godet, T., Gonnert, F., Gouhier, C., Goury, A., Guerin, R., Guillon, A., Guyon, M., Hartmann, O., Haucke, A., Hecketsweiler, S., Heenen, S., Hemelaar, P., Henin, P., Henker, R., Henry-Lagarrigue, M., Herafa, I., Heunks, L., Hoedemaekers, A., Hohn, A., Hollinger, A., Huberlant, V., Huot, B., Jabaudon, M., Jacob, L., Janisch, T., Jaschinski, U., Joret, A., Jouan, Y., Kehl, L., Kelly, D. S., Kerdjana, L., Kerinn, M., Kerymel, M., Kluge, S., Kohlberg, K. K., Kolanos, S., Kortgen, A., Kreuser, I., Kummerlen, C., La Combe, B., La Foucher, B., Lacherade, J. -C., Lafon, C., Laissi, M., Laleu, S., Lascarrou, J. -B., Lascarrou, J. B., Lasocki, S., Laterre, P. -F., Laterre, P. F., Launoy, A., Laurent, Y., Lebert, C., Leblanc, D., Lebreton, S., Legall, C., Legrand, M., Legras, A., Lematte, M., Leone, F. E., Lessinger, J. -M., Letrou, S., Lindau, S., Loiez, A., Louadah, B., Lucht, A., Ludes, P. O., Mabilat, C., Magalhaes, E., Mairesse, J., Malissin, I., Mancia, C., Manivet, P., Maquigneau, N., Martin-Levevre, L., Marx, G., Marx, N., Massat, S., Mebazaa, A., Megarbane, B., Meier, B., Meier-Hellmann, A., Meinig, T., Mercier, E., Messika, J., Metzger, C., Meybohm, P., Meyer, A., Meziani, F., Mourvillier, B., Muller, J., Mutlak, H., Navarin, S., Neuville, M., Nierhaus, A., Nouaille, M., Orru, M., Oueslati, H., Papendorp, S., Pascal, J., Perbet, S., Petre, H., Pezechk, J., Pichon, N., Pickkers, P., Pierre, V., Pottecher, J., Quatrocchi, D., Quattrochi, D., Rabouel, Y., Radji, S., Radjou, A., Rahmani, H., Reignier, J., Renard, S., Ricard, J. -D., Ringeis, G., Rinket, M., Robert, A., Robin, L., Rodier, N., Rolhion, C., Rommer, M., Roovers, N., Roszyk, L., Rouleau, S., Rousseau, C., Rouve, E., Roux, D., Ruimy, A., Russo, V., Salmon, C., Schedler, D., Schindler, A., Schnell, D., Schreiber, J., Schroder, D., Schuerholz, T., Schwope, K., Scigalla, P., Sebastien, L., Sensen, B., Siedler, S., Siewecke, A., Simeon-Vieules, V., Simon, T. -P., Simona, S., Singer, B., Soffker, G., Sonneville, R., Soyer, B., Struck, J., Szozot, M., Thibault, S., Thirifays, A., Thomas-Ruddel, D., Timsit, J. -F., Trine, H., Trof, R. J., Vallecoccia, M. S., Van Der Hoeven, H., Van Wezel, H., Varchetta, A., Verlhac, C., Vermeijden, J., Victori, G., Vignon, P., Vinatier, I., Vinetti, M., Voicu, S., Wetsch, W., Wichmann, D., Wittebole, X., Yehia, A., Zacharowski, K. D., Zanquila, M., Zapatero, D. C., Zinzonni, V. E., Zoccoli, G. +274 morecore +1 more sourceThe effects of ultrasound exposure on P-glycoprotein-mediated multidrug resistance in vitro and in vivo
Journal of Experimental & Clinical Cancer Research, 2018 Background Multidrug resistance (MDR) is often responsible for the failure of chemotherapy treatment, and current strategies for cancer MDR are not adequately satisfying as to their efficacy and safety.Chixiong Huang, Senlin Huang, Hairui Li, Xinzhong Li, Bing Li, Lintao Zhong, Junfeng Wang, Meishen Zou, Xiang He, Hao Zheng, Xiaoyun Si, Wangjun Liao, Yulin Liao, Li Yang, Jianping Bin +14 moredoaj +1 more sourceSLC35E1 promotes keratinocyte proliferation in psoriasis by regulating zinc homeostasis
Cell Death and Disease, 2023 Keratinocyte hyperproliferation is a key pathogenic factor in psoriasis. However, the mechanisms that regulate keratinocyte hyperproliferation in this condition remain unclear. Here, we found that SLC35E1 was highly expressed in keratinocytes of patients Tao Huang, Shijun Chen, Ke Ding, Baoqing Zheng, Weiqi Lv, Xiaobo Wang, Yadan Zhong, Hongxin Huang, Xin Zhang, Shufeng Ma, Bin Yang, Xiaohua Wang, Zhili Rong +12 moredoaj +1 more sourceHepatic artery pseudoaneurysm ligation after orthotopic liver transplantation-a report of 7 cases [PDF]
, 1992 Pseudoaneurysm (PA) is a rare but life-threatening complication of liver transplantation. The authors present their experience on 7 patients treated by ligation of a post-OLT PA.Gordon, R, Madariaga, J, Starzl, TE, Tepetes, K, Todo, S, Tzakis, A, Tzoracoleftherakis, E, Zajko, AB +7 morecore +1 more sourceAssociation between admission plasma 2-oxoglutarate levels and short-term outcomes in patients with acute heart failure: a prospective cohort study
Molecular Medicine, 2019 Background 2-oxoglutarate (2OG), an intermediate metabolite in the tricarboxylic acid cycle, has been found to associate with chronic heart failure (HF), but its effect on short-term adverse outcomes in patients with acute HF (AHF) is uncertain.Zhengliang Peng, Qiong Zhan, Xiangkun Xie, Hanlin Li, Yan Tu, Yujia Bai, Xingfu Huang, Wenyan Lai, Boxin Zhao, Qingchun Zeng, Dingli Xu +10 moredoaj +1 more sourceTargeted inhibition of PTPN22 is a novel approach to alleviate osteogenic responses in aortic valve interstitial cells and aortic valve lesions in mice
BMC Medicine, 2023 Background Calcific aortic valve disease (CAVD) is the most prevalent valvular disease and has high morbidity and mortality. CAVD is characterized by complex pathophysiological processes, including inflammation-induced osteoblastic differentiation in ...Shunyi Li, Zichao Luo, Shuwen Su, Liming Wen, Gaopeng Xian, Jing Zhao, Xingbo Xu, Dingli Xu, Qingchun Zeng +8 moredoaj +1 more sourceAssessment of cerebral microbleeds by susceptibility-weighted imaging at 3T in patients with end-stage organ failure [PDF]
, 2018 Purpose: Cerebral microbleeds (CMBs) are small rounded lesions representing cerebral hemosiderin deposits surrounded by macrophages that results from previous microhemorrhages.Cannella, Roberto, Gambino, Angelo, Lo Re, Vincenzina, Mamone, Giuseppe, Miraglia, Roberto, Sparacia, Gianvincenzo +5 morecore +1 more sourceEngineered Cas12a-Plus nuclease enables gene editing with enhanced activity and specificity
BMC Biology, 2022 Background The CRISPR-Cas12a (formerly Cpf1) system is a versatile gene-editing tool with properties distinct from the broadly used Cas9 system. Features such as recognition of T-rich protospacer-adjacent motif (PAM) and generation of sticky breaks, as ...Hongxin Huang, Guanjie Huang, Zhihong Tan, Yongfei Hu, Lin Shan, Jiajian Zhou, Xin Zhang, Shufeng Ma, Weiqi Lv, Tao Huang, Yuchen Liu, Dong Wang, Xiaoyang Zhao, Ying Lin, Zhili Rong +14 moredoaj +1 more source
