Results 11 to 20 of about 2,772,477 (308)

Association of Sequential Organ Failure Assessment (SOFA) components with mortality [PDF]

, 2022
BACKGROUND Sequential Organ Failure Assessment (SOFA) is a practical method to describe and quantify the presence and severity of organ system dysfunctions and failures. Some proposals suggest that SOFA could be employed as an endpoint in trials.
Pekkarinen, Pirkka T, Tuomas Selander, Reinikainen, Matti, Jukka Takala, Anssi Pölkki, Selander, Tuomas, Pekkarinen, Pirkka T., Pölkki, Anssi, Takala, Jukka, Pirkka T. Pekkarinen, Matti Reinikainen   +10 more
core   +2 more sources

Editor: The Organ Manual Issue 5 January 2023 [PDF]

, 2023
Editor of The Organ Manual ...
Okpoti, Rebekah
core   +3 more sources

Moderate-Intensity Exercise Affects Gut Microbiome Composition and Influences Cardiac Function in Myocardial Infarction Mice

Frontiers in Microbiology, 2017
Physical exercise is commonly regarded as protective against cardiovascular disease (CVD). Recent studies have reported that exercise alters the gut microbiota and that modification of the gut microbiota can influence cardiac function.
Zuheng Liu, Zuheng Liu, Hai-Yue Liu, Hai-Yue Liu, Haobin Zhou, Haobin Zhou, Qiong Zhan, Qiong Zhan, Wenyan Lai, Wenyan Lai, Qingchun Zeng, Qingchun Zeng, Hao Ren, Hao Ren, Dingli Xu, Dingli Xu   +15 more
doaj   +1 more source

Incidence of individual organ dysfunction in fatal acute pancreatitis: analysis of 1024 death records [PDF]

, 2009
Background: Extrapancreatic organ dysfunction is the key determinant of mortality in acute pancreatitis (AP). This study aimed to document the frequency and duration of individual organ dysfunction in all fatalities caused by AP in a large, population ...
Parks, Rowan W.; id_orcid, Bayanne Olabi, Garden, O. James, Parks, Rowan W., O. James Garden, Mole, DJ, Robinson, Victoria, Damian J. Mole, Olabi, Bayanne, Victoria Robinson, Mole, Damian J., Parks, RW, Garden, OJ, Olabi, B, Robinson, V, Rowan W. Parks   +15 more
core   +1 more source

An efficacy and mechanism evaluation study of Levosimendan for the Prevention of Acute oRgan Dysfunction in Sepsis (LeoPARDS): protocol for a randomized controlled trial. [PDF]

, 2014
BACKGROUND: Organ dysfunction consequent to infection ('severe sepsis') is the leading cause of admission to an intensive care unit (ICU). In both animal models and early clinical studies the calcium channel sensitizer levosimendan has been demonstrated ...
McAuley, Daniel F, Orme, RML, Singer, M, L'E Orme, Robert M, Alexina J Mason, McAuley DF, Mason, Alexina J., Orme, Robert M L'E, Ashby D, Orme, Robert M., Mason, Alexina J, Liu, KD, Perkins, Gavin D., McAuley, Daniel F.; id_orcid, Gordon, Anthony C., Robert M Orme, Daniel F McAuley, Mason, AJ, Gordon, Anthony C, Gordon AC, Liu, Kathleen D., Orme RM, Gordon, AC, Mervyn Singer, Perkins, GD, Kathleen D Liu, Mason AJ, McAuley, Daniel F., Liu KD, Andrea Morelli, Ashby, D, Liu, Kathleen, Liu, Kathleen D, Gavin D Perkins, Morelli, A, Singer, Mervyn, Singer M, Perkins, Gavin D, Ashby, Deborah, Anthony C Gordon, Deborah Ashby, Orme, Robert MLE, Morelli, Andrea, Perkins GD, McAuley, DF   +44 more
core   +1 more source

Sirt1 Antisense Long Noncoding RNA Promotes Cardiomyocyte Proliferation by Enhancing the Stability of Sirt1

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Antisense long noncoding RNAs (lncRNAs) are single‐stranded RNAs that overlapped gene‐coding regions on the opposite DNA strand and play as critical regulators in cardiovascular diseases.
Bing Li, Yinlan Hu, Xinzhong Li, Guoqing Jin, Xiaoqiang Chen, Guojun Chen, Yanmei Chen, Senlin Huang, Wangjun Liao, Yulin Liao, Zhonghua Teng, Jianping Bin   +11 more
doaj   +1 more source

Patterning the geographies of organ transplantation: corporeality, generosity and justice [PDF]

, 2006
Organ transplantation is now an established treatment for patients with end-stage organ failure, yet there are spatial inequalities in access to this procedure.
Gail Davies, Davies, G, Davies, Gail
core   +1 more source

The effects of ultrasound exposure on P-glycoprotein-mediated multidrug resistance in vitro and in vivo

Journal of Experimental & Clinical Cancer Research, 2018
Background Multidrug resistance (MDR) is often responsible for the failure of chemotherapy treatment, and current strategies for cancer MDR are not adequately satisfying as to their efficacy and safety.
Chixiong Huang, Senlin Huang, Hairui Li, Xinzhong Li, Bing Li, Lintao Zhong, Junfeng Wang, Meishen Zou, Xiang He, Hao Zheng, Xiaoyun Si, Wangjun Liao, Yulin Liao, Li Yang, Jianping Bin   +14 more
doaj   +1 more source

SLC35E1 promotes keratinocyte proliferation in psoriasis by regulating zinc homeostasis

Cell Death and Disease, 2023
Keratinocyte hyperproliferation is a key pathogenic factor in psoriasis. However, the mechanisms that regulate keratinocyte hyperproliferation in this condition remain unclear. Here, we found that SLC35E1 was highly expressed in keratinocytes of patients
Tao Huang, Shijun Chen, Ke Ding, Baoqing Zheng, Weiqi Lv, Xiaobo Wang, Yadan Zhong, Hongxin Huang, Xin Zhang, Shufeng Ma, Bin Yang, Xiaohua Wang, Zhili Rong   +12 more
doaj   +1 more source

Disease severity adversely affects delivery of dialysis in acute renal failure [PDF]

, 2007
Background/Aims: Methods of intermittent hemodialysis (IHD) dose quantification in acute renal failure (ARF) are not well defined. This observational study was designed to evaluate the impact of disease activity on delivered single pool Kt/V-urea in ARF ...
Schiffl, Helmut
core   +1 more source