IL-1α and TNF-α Down-Regulate CRH Receptor-2 mRNA Expression in the Mouse Heart [PDF]
, 2001 Two receptors (CRH receptor type 1 and CRH receptor type 2) have been identified for the stress-induced neuropeptide, CRH and related peptides, urocortin, and urocortin II.
Coste, Sarah C. +4 more
core +2 more sources
Advanced Synthesis &Catalysis, Volume 368, Issue 9, 5 May 2026.The enantioselective synthesis of naphthocoumarin adducts via a tandem organocatalytic 1,4‐addition/decarboxylation delivers excellent control over a newly forged stereocenter and yields configurationally stable synclinal atropisomers. The process features broad substrate scope and scalability, and its structural and mechanistic foundations are ...
M. Chiara Cabua +10 more
wiley +1 more source
The Development of a Single Frequency Place in the Mammalian Cochlea: The Cochlear Resonance in the Mustached Bat Pteronotus parnellii [PDF]
, 2003 Cochlear microphonic potentials (CMs) were recorded from the sharply tuned, strongly resonant auditory foveae of 1- to 5-week-old mustached bats that were anesthetized with Rompun and Ketavet.
Drexl, Markus +4 more
core +2 more sources
A Conceptual Framework for Assessing Soil Structural Attributes Across Contrasting Land‐Use Types
European Journal of Soil Science, Volume 77, Issue 3, May–June 2026.ABSTRACT Soil structure governs ecosystem functioning across scales, but its complexity requires integrative approaches that capture geometric and functional properties. This study proposes a methodological framework that integrates field‐based visual evaluation of soil structure (VESS), X‐ray computed tomography (CT) and soil hydraulic property (SHP ...
Niklas Schmücker +4 more
wiley +1 more source
Optimal management of Cogan’s syndrome: a multidisciplinary approach [PDF]
, 2017 Cogan's syndrome (CS) is a rare disorder characterized by nonsyphilitic interstitial keratitis (IK) and audio-vestibular symptoms. CS affects mainly young Caucasian adults, mostly during their first three decades of age, and may develop into typical and ...
D'Aguanno, Vittorio +3 more
core +1 more source
Journal of Otolaryngology - Head and Neck SurgeryImportance Mesenchymal stem cells (MSCs) have the capability of providing ongoing paracrine support to degenerating tissues. Since MSCs can be extracted from a broad range of tissues, their specific surface marker profiles and growth factor secretions ...
Marc J. W. Lammers MD, PhD +7 more
doaj +1 more source
Cochlear progenitor number is controlled through mesenchymal FGF receptor signaling
eLife, 2015 The sensory and supporting cells (SCs) of the organ of Corti are derived from a limited number of progenitors. The mechanisms that regulate the number of sensory progenitors are not known.
Sung-Ho Huh +2 more
doaj +1 more source
Studies of intercellular Ca2+ signaling and gap-junction coupling in the developing cochlea of mouse models affected by congenital hearing loss [PDF]
, 2013 Connexin 26 (Cx26) and connexin 30 (Cx30) form gap junction channels that allow the intercellular diffusion of the Ca2+ mobilizing second messenger IP3.
Rodriguez Hernandez, Laura
core +1 more source
Cooperativity of Kv7.4 channels confers ultrafast electromechanical sensitivity and emergent properties in cochlear outer hair cells. [PDF]
, 2020 The mammalian cochlea relies on active electromotility of outer hair cells (OHCs) to resolve sound frequencies. OHCs use ionic channels and somatic electromotility to achieve the process.
Chiamvimonvat, Nipavan +12 more
core +1 more source
PLoS Genetics, 2019 The mouse organ of Corti, housed inside the cochlea, contains hair cells and supporting cells that transduce sound into electrical signals. These cells develop in two main steps: progenitor specification followed by differentiation.
Lu M Yang +3 more
doaj +1 more source