Results 71 to 80 of about 62,689 (299)
Organ-on-a-chip platforms for evaluation of environmental nanoparticle toxicity
Bioactive Materials, 2021 Despite showing a great promise in the field of nanomedicine, nanoparticles have gained a significant attention from regulatory agencies regarding their possible adverse health effects upon environmental exposure.
Rick Xing Ze Lu, Milica Radisic
doaj +1 more source
One-step fabrication of an organ-on-a-chip with spatial heterogeneity using a 3D bioprinting technology [PDF]
, 2018 Although various types of organs-on-chips have been introduced recently as tools for drug discovery, the current studies are limited in terms of fabrication methods.
Lee, H, Cho, DW
core +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Mimicking and surpassing the xenograft model with cancer-on-chip technology
EBioMedicine, 2021 Organs-on-chips are in vitro models in which human tissues are cultured in microfluidic compartments with a controlled, dynamic micro-environment. Specific organs-on-chips are being developed to mimic human tumors, but the validation of such ‘cancer-on ...
Job Komen +4 more
doaj +1 more source
3D Printing of Organs-On-Chips [PDF]
Bioengineering, 2017 Organ-on-a-chip engineering aims to create artificial living organs that mimic the complex and physiological responses of real organs, in order to test drugs by precisely manipulating the cells and their microenvironments. To achieve this, the artificial organs should to be microfabricated with an extracellular matrix (ECM) and various types of cells ...
YI, HEE GYEONG +2 more
openaire +4 more sources
, 2020 Cell-cell communication plays a pivotal role in the coordination and function of biological systems. Three-dimensional (3D) cellular constructs provide venues to explore cellular communication for tissue development and drug discovery, as their 3D ...
Anna Kalmykov (4933954)
core +1 more source
Bioinspired human stomach-on-a-chip with in vivo like function and architecture
, 2023 The lack of biomimetic in vitro models capable of reproducing the complex architecture and the dynamic environment of the gastric mucosa, delay the development of diagnostic and therapeutic tools.
Oliveira, Carla; orcid: +5 more
core +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
Developments and Applications of Liver-on-a-Chip Technology—Current Status and Future Prospects
BiomedicinesBackground/Objectives: Liver-on-a-chip (LiOC) technology is increasingly recognized as a transformative platform for modeling liver biology, disease mechanisms, drug metabolism, and toxicity screening.
Joseph Mugaanyi +5 more
doaj +1 more source