Results 1 to 10 of about 298,035 (357)

Organ preservation: current limitations and optimization approaches [PDF]

Frontiers in Medicine
Despite the annual rise in patients with end-stage diseases necessitating organ transplantation, the scarcity of high-quality grafts constrains the further development of transplantation.
Qiulin Ran, Jiayi Zhang, Jisheng Zhong, Ji Lin, Shuai Zhang, Guang Li, Bin You   +6 more
doaj   +2 more sources

The European Larynx Organ Preservation Study [MK-3475-C44] [PDF]

Frontiers in Oncology
The European Larynx Organ Preservation Study (ELOS; NCT06137378) is a prospective, randomized, open-label, two-armed parallel group controlled, phase II multicenter larynx organ preservation (LOP) trial in locoregionally advanced (LA) stage III, IVA/B ...
Gunnar Wichmann, Gunnar Wichmann, Theresa Wald, Theresa Wald, Markus Pirlich, Markus Pirlich, Joanna Napp, Ina Münter, Thomas Asendorf, Ralf Tostmann, Jeannette Vogt, Jeannette Vogt, Kathrin Vogel, Kathrin Vogel, Sylvia Meuret, Sylvia Meuret, Matthaeus Stoehr, Matthaeus Stoehr, Veit Zebralla, Veit Zebralla, Nils Henrik Nicolay, Nils Henrik Nicolay, Thomas Kuhnt, Thomas Kuhnt, Peter Hambsch, Peter Hambsch, Orlando Guntinas-Lichius, Orlando Guntinas-Lichius, Jens Peter Klußmann, Susanne Wiegand, Susanne Wiegand, Susanne Wiegand, Andreas Dietz, Andreas Dietz   +33 more
doaj   +2 more sources

Nanotechnology-driven advancements in organ transplantation: Multifaceted strategies for organ preservation, ischemia reperfusion injury, immunomodulation and post-transplant monitoring [PDF]

Materials Today Bio
Organ transplantation faces critical challenges, including donor shortages, suboptimal preservation, ischemia-reperfusion injury (IRI), and immune rejection.
Ziyin Chen, Mingxiao Zhang, Congrong Shen, Xinyu Zhao, Jianfeng Wang, Xianwen Wang   +5 more
doaj   +2 more sources

Editorial: Organ preservation for rectal cancer patients [PDF]

Frontiers in Surgery
Ionut Negoi, John R. T. Monson, Leonardo Bustamante-Lopez, Leonardo Bustamante-Lopez, Zoe Garoufalia, Vito D'Andrea, Sameh Hany Emile   +6 more
doaj   +2 more sources

Vascular Microphysiological System for Investigating Endothelial Barrier Function During Organ Preservation and Reperfusion. [PDF]

Small
Kim Y, Goswami I, Gill E, Mahmoodi SR, Consiglio AN, Velazquez J, Nieman G, Alburo AAA, Woods B, Ellis BW, Filz von Reiterdank I, Uygun K, Uygun BE, Rubinsky B, Healy KE.   +14 more
europepmc   +3 more sources

Establishment of Functional Liver Spheroids From Human Hepatocyte-Derived Liver Progenitor-Like Cells for Cell Therapy

Frontiers in Bioengineering and Biotechnology, 2021
Globally, about two million people die from liver diseases every year. Liver transplantation is the only reliable therapy for severe end-stage liver disease, however, the shortage of organ donors is a huge limitation.
Wen-Ming Liu, Wen-Ming Liu, Xu Zhou, Xu Zhou, Cai-Yang Chen, Cai-Yang Chen, Dong-Dong Lv, Wei-Jian Huang, Wei-Jian Huang, Yuan Peng, Hong-Ping Wu, Yi Chen, Yi Chen, Dan Tang, Dan Tang, Li-Na Guo, Xiu-Li Wang, Hong-Dan Zhang, Xiao-Hua Liu, Xiao-Hua Liu, Li-Qun Yang, Li-Qun Yang, Wei-Feng Yu, Wei-Feng Yu, He-Xin Yan, He-Xin Yan, He-Xin Yan, He-Xin Yan   +27 more
doaj   +1 more source

Isochoric Supercooling Organ Preservation System

Bioengineering, 2023
This technical paper introduces a novel organ preservation system based on isochoric (constant volume) supercooling. The system is designed to enhance the stability of the metastable supercooling state, offering potential long-term preservation of large ...
Gabriel Năstase, Florin Botea, George-Andrei Beșchea, Ștefan-Ioan Câmpean, Alexandru Barcu, Ion Neacșu, Vlad Herlea, Irinel Popescu, Tammy T. Chang, Boris Rubinsky, Alexandru Șerban   +10 more
doaj   +1 more source

Organ Repair and Regeneration During Ex Situ Dynamic Preservation: The Future is Nano

Transplant International, 2023
Organ preservation and assessment with machine perfusion (MP) has provided transplant physicians with the ability to evaluate and select grafts suitable for transplantation.
Nicholas Gilbo, Nicholas Gilbo, Joris Blondeel, Joris Blondeel, Jacques Pirenne, Jacques Pirenne, Renato Romagnoli, Renato Romagnoli, Giovanni Camussi, Giovanni Camussi, Diethard Monbaliu, Diethard Monbaliu   +11 more
doaj   +1 more source

Recent Advances in Organ Preservation Solutions and Methods for Using in Liver and Kidney Transplantation

مجله دانشکده پزشکی اصفهان, 2020
Background: The organ transplantation has been developed due to recent advances in transplantation surgery. The method of preservation and the type of preserving solution are determining factors in the outcome of the transplantations.
Zahra Jamadi, Parinaz Parhizgar, Ghasem Yazdanpanah, Tahereh Tayebi, Roghayeh Tarasi, Hassan Niknejad   +5 more
doaj   +1 more source

Benign and malignant renal cells are differentially inhibited during prolonged organ preservation. [PDF]

PLoS ONE, 2013
The worry of potential residual renal cancer cells in donor kidney after resection of small renal cancer impedes the extensive use of such controversial donor source.
Nengwang Yu, Shuai Fu, Yubao Liu, Zhihou Fu, Jianzhong Meng, Zhonghua Xu, Baocheng Wang, Aimin Zhang   +7 more
doaj   +1 more source