Results 1 to 10 of about 104,226 (75)
Trends in organ preservation [PDF]
Organ preservation aims to provide a viable graft with primary function post-transplant. The current basis of preservation for transplantation is static cold storage using specific preservation solutions which minimise cellular swelling and membrane pump activity, thus maintaining cellular ATP levels. The current organ shortage and consequent expansion
McLaren, A, Friend, P
openaire +3 more sources
Normothermic organ preservation [PDF]
Abstract Although organ preservation has relied upon hypothermia throughout the history of clinical transplantation, increasing reliance on suboptimal organs has recently focused attention on novel techniques that avoid the cumulative effects of preexisting organ damage and cold preservation.
Jamieson, R, Friend, P
openaire +2 more sources
Organ reperfusion and preservation
Organ transplantation is one of the medical success stories of the 20th century. Transplantation is, however, a victim of its own success with demand for organs far exceeding supply. The ischemia/reperfusion injury associated with organ transplantation is complex with interlinking cellular pathways and cascades.
Jamieson, R, Friend, P
openaire +3 more sources
Blockchain-Powered Supply Chain Management for Kidney Organ Preservation [PDF]
Due to the shortage of available kidney organs for transplants, handling every donor kidney with utmost care is crucial to preserve the organ's health, especially during the organ supply chain where kidneys are prone to deterioration during transportation.
arxiv
Perspectives in Organ Preservation
Maintaining organ viability after donation until transplantation is critically important for optimal graft function and survival. To date, static cold storage is the most widely used form of preservation in every day clinical practice. Although simple and effective, it is questionable whether this method is able to prevent deterioration of organ ...
Maathuis, M, Leuvenink, H, Ploeg, R
openaire +4 more sources
Organ preservation: which temperature for which organ? [PDF]
In 1954, Joseph Murray performed the first successful human organ transplant from a live kidney donor, Richard Herrick, into the donor’s twin, Robert. Since no form of organ preservation was available, the surgeries happen in two simultaneous operating rooms.
Bellini, Maria Irene, D’Andrea, Vito
openaire +4 more sources
Experimental organ preservation
Abstract An experimental model for the study of organ preservation based on the isolated, biologically perfused rat heart is described. Using this model a standard storage solution has been evolved for use with initial perfusion and hypothermic storage. This solution contains Dextran 40 and insulin.
Calman Kc, P. R. F. Bell
openaire +4 more sources
SA-GAN: Structure-Aware GAN for Organ-Preserving Synthetic CT Generation [PDF]
In medical image synthesis, model training could be challenging due to the inconsistencies between images of different modalities even with the same patient, typically caused by internal status/tissue changes as different modalities are usually obtained at a different time.
arxiv
Self-organized criticality in deterministic systems with disorder [PDF]
Using the Bak-Sneppen model of biological evolution as our paradigm, we investigate in which cases noise can be substituted with a deterministic signal without destroying Self-Organized Criticality (SOC). If the deterministic signal is chaotic the universality class is preserved; some non-universal features, such as the threshold, depend on the time ...
arxiv +1 more source
Self-Organizing Time Map: An Abstraction of Temporal Multivariate Patterns [PDF]
This paper adopts and adapts Kohonen's standard Self-Organizing Map (SOM) for exploratory temporal structure analysis. The Self-Organizing Time Map (SOTM) implements SOM-type learning to one-dimensional arrays for individual time units, preserves the orientation with short-term memory and arranges the arrays in an ascending order of time.
arxiv +1 more source