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2006
The success of organ transplantation is critically dependent on the quality of the donor organ. Donor organ quality, in turn, is determined by a variety of factors including donor age and preexisting disease, the mechanism of brain death, donor management prior to organ procurement, the duration of hypothermic storage, and the circumstances of ...
Mark, Hicks +4 more
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The success of organ transplantation is critically dependent on the quality of the donor organ. Donor organ quality, in turn, is determined by a variety of factors including donor age and preexisting disease, the mechanism of brain death, donor management prior to organ procurement, the duration of hypothermic storage, and the circumstances of ...
Mark, Hicks +4 more
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Controversy in Organ Preservation
Urologic Clinics of North America, 1976Renal preservation has contributed to improvements in human cadaver kidney transplantation in terms of viability testing and logistics. Unfortunately, the antigenicity of a kidney has not been reduced by our present preservation methods; consequently, immunologic problems in cadaver kidney transplantation still remain.
M O, Magnusson, N T, Stowe
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Surgical Clinics of North America, 1986
This article briefly explores the mechanisms of ischemic damage and then considers the effects of cooling and other supplementary measures that can protect organs during storage. Clinical applications of this information are considered, and likely avenues for future improvements in techniques for organ preservation are discussed.
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This article briefly explores the mechanisms of ischemic damage and then considers the effects of cooling and other supplementary measures that can protect organs during storage. Clinical applications of this information are considered, and likely avenues for future improvements in techniques for organ preservation are discussed.
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Problems of Organ Preservation ORGAN PRESERVATION
Transplantation, 1967SUMMARYStorage in an intermediate host has permitted better and longer (5 days) preservation of a dog kidney than any other method.Perfusion with hypothermia, as well as hyperbaric oxygen and hypothermia, has in isolated instances permitted successful reimplantation after 3 days storage.Simple ...
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Perfusion, 1991
Clinical heart transplantation began in December 1967 when Cristiaan Barnard performed the first human to human heart transplant on a 57 year old man with ischaemic heart disease, in Cape Town. This ushered in a bout of enthusiastic heart transplantations world-wide over the subsequent few years which soon waned as the problems of acute rejection and ...
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Clinical heart transplantation began in December 1967 when Cristiaan Barnard performed the first human to human heart transplant on a 57 year old man with ischaemic heart disease, in Cape Town. This ushered in a bout of enthusiastic heart transplantations world-wide over the subsequent few years which soon waned as the problems of acute rejection and ...
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Normothermic preservation of isolated organs
Journal of Biomedical Engineering, 1981Abstract Many perfusional techniques have already been described for the preservation of isolated organs, but we present here the basic problems at cellular level regarding functional preservation. The technique we use permits physiological and pharmacological studies on isolated organs and may also be helpful in the development of long term ...
J B, Buchs +3 more
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Organ Preservation for Rectal Cancer
Journal of Clinical Oncology, 2007Organ preservation with maintenance of function in the treatment of rectal cancer is highly valued by patients. Although most patients with resectable rectal cancer can undergo a sphincter-sparing radical procedure, there are patient, tumor, surgeon, and treatment factors that influence the ability to restore intestinal continuity after radical ...
Nancy N, Baxter, Julio, Garcia-Aguilar
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Nihon Geka Gakkai zasshi, 1997
Organ procurement is the first step of organ preservation. We have developed "in situ machine wash out technique with CMH solution" for the purpose of rapid cooling and complete elimination of blood. The utility of this technique was confirmed by both experimentally and clinically. Two major techniques have been used for organ preservation.
T, Asano, T, Kenmochi, K, Isono
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Organ procurement is the first step of organ preservation. We have developed "in situ machine wash out technique with CMH solution" for the purpose of rapid cooling and complete elimination of blood. The utility of this technique was confirmed by both experimentally and clinically. Two major techniques have been used for organ preservation.
T, Asano, T, Kenmochi, K, Isono
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Viability assays in organ preservation
Cryobiology, 1989Assays to determine the viability of preserved organs ideally must meet two important requirements: (i) in the clinical environment, they should allow the surgeon to determine if an organ will be viable when it is transplanted (this needs to be done in a noninvasive, nondestructive manner, and currently no such assay exists), and (ii) in the research ...
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Medicina intensiva, 2009
Maintaining organ viability from extraction to transplantation is crucial to ensure the function and survival of the graft. In recent years, maintaining organ viability has become more challenging because the shortage of donors has led to broader criteria for donor acceptability and consequently to organs with greater compromise.
José Luis Escalante, Cobo +1 more
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Maintaining organ viability from extraction to transplantation is crucial to ensure the function and survival of the graft. In recent years, maintaining organ viability has become more challenging because the shortage of donors has led to broader criteria for donor acceptability and consequently to organs with greater compromise.
José Luis Escalante, Cobo +1 more
openaire +1 more source