Results 81 to 90 of about 1,992,155 (390)

Fertility preservation in ovarian tumours [PDF]

open access: yes, 2018
A considerable number of patients with a cancer diagnosis are of childbearing age and have not satisfied their desire for a family. Despite ovarian cancer (OC) usually occurring in older patients, 3%–14% are diagnosed at a fertile age with the overall 5 ...
Bardhi, E.   +8 more
core   +1 more source

Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury

open access: yesFEBS Letters, EarlyView.
Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung   +6 more
wiley   +1 more source

Investigation of the Uniformity of Gel Shrinkage by Imaging Tracer Particles Using X‐Ray Microtomography

open access: yesAdvanced Engineering Materials, EarlyView., 2023
A novel method for tracking structural changes in gels using widely accessible microcomputed tomography is presented and validated for various hydro‐, alco‐, and aerogels. The core idea of the method is to track positions of micrometer‐sized tracer particles entrapped in the gel and relate them to the density of the gel network.
Anja Hajnal   +3 more
wiley   +1 more source

Revisiting the Principles of Preservation in an Era of Pandemic Obesity

open access: yesFrontiers in Immunology, 2022
The current obesity epidemic has caused a significant decline in the health of our donor population. Organs from obese deceased donors are more prone to ischemia reperfusion injury resulting from organ preservation.
John T. Langford   +8 more
doaj   +1 more source

Organ transplantation--then and now. [PDF]

open access: yes, 1987
The last 25 years have seen amazing progress in transplantation--from the development of techniques for immunosuppression to methods for organ removal and preservation.
Makowka, L, Starzl, TE
core  

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

open access: yesFEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Finding the Sweet Spot for Data Anonymization: A Mechanism Design Perspective [PDF]

open access: yesarXiv, 2021
Data sharing between different organizations is an essential process in today's connected world. However, recently there were many concerns about data sharing as sharing sensitive information can jeopardize users' privacy. To preserve the privacy, organizations use anonymization techniques to conceal users' sensitive data. However, these techniques are
arxiv  

Privacy Preserving Vertical Federated Learning for Tree-based Models [PDF]

open access: yes, 2020
Federated learning (FL) is an emerging paradigm that enables multiple organizations to jointly train a model without revealing their private data to each other. This paper studies {\it vertical} federated learning, which tackles the scenarios where (i) collaborating organizations own data of the same set of users but with disjoint features, and (ii ...
arxiv   +1 more source

The Role of Hormones and Trophic Factors as Components of Preservation Solutions in Protection of Renal Function before Transplantation: A Review of the Literature

open access: yesMolecules, 2020
Transplantation is currently a routine method for treating end-stage organ failure. In recent years, there has been some progress in the development of an optimal composition of organ preservation solutions, improving the vital functions of the organ and
Aneta Ostróżka-Cieślik   +1 more
doaj   +1 more source

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