Results 91 to 100 of about 97,814 (298)

Organ Preservation in Rectal Cancer: The Patients' Perspective

Frontiers in Oncology, 2019
Organ preservation after a clinical complete response to radiochemotherapy is currently one of the most discussed topics in the management of rectal cancer. However, the patients' perspective has only been poorly studied so far. In this multicenter study,
Cihan Gani, Cihan Gani, Cihan Gani, Nina Gani, Sebastian Zschaeck, Fabian Eberle, Norbert Schaeffeler, Thomas Hehr, Bernhard Berger, Stefan Georg Fischer, Johannes Claßen, Stephan Zipfel, Claus Rödel, Martin Teufel, Martin Teufel, Daniel Zips, Daniel Zips   +16 more
doaj   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Opportunities and challenges with the implementation of normothermic machine perfusion in kidney transplantation

Nature Communications
End stage kidney disease and dialysis are lifetime limiting and lifestyle-defining conditions with enormous costs to the health care system. Despite a severe organ shortage, thousands of organs that are retrieved for transplantation go to waste every ...
Ton J. Rabelink, Sarah Hosgood, Thomas Minor, Markus Selzner, Annemarie Weissenbacher, Henri GD Leuvenink, Stefan Schneeberger   +6 more
doaj   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

Absence of Exogenous Glucose in the Perfusate During Kidney Hypothermic Machine Perfusion Does Not Affect Mitochondrial Function

Background: Optimizing organ preservation techniques is imperative in the face of donor kidney shortage and high waiting list mortality. Hypothermic machine perfusion (HMP) has emerged as an effective method to improve graft function post-transplantation,
Henri G. D. Leuvenink, Barbara M. Bakker, Leonie H. Venema, Jan-Luuk Hillebrands, Dafni Efraimoglou, L. Annick van Furth, Albert Gerding   +6 more
core   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Linear accelerator-based stereotactic fractionated photon radiotherapy as an eye-conserving treatment for uveal melanoma

Radiation Oncology, 2018
Background The purpose of this retrospective analysis is to analyze clinical outcome, visual acuity and enucleation rates after linear accelerator-based stereotactic fractionated photon radiotherapy for primary uveal melanoma.
Sati Akbaba, Robert Foerster, Nils Henrik Nicolay, Nathalie Arians, Tilman Bostel, Juergen Debus, Henrik Hauswald   +6 more
doaj   +1 more source

Organ donation Week 3 - Organ preservation and transport

, 2017
This video focuses on organ preservation and transportation. The video defines what ischaemia is and how it plays a role in the organ transportation and preservation process.
Thomson, David
core  

DAMPs and NLRP3 Inflammasome Response in Fatty Liver Grafts Preservation in Different Preservation Solutions

, 2020
Resumen del trabajo presentado en el American Transplant Congress 2020, originalmente programado para tener lugar en Filadelfia (Estados Unidos), se convirtió en un Congreso Virtual debido a COVID-19, celebrado del 30 de mayo al 3 de junio de 2020Purpose:
Folch-Puy, Emma, Panisello-Roselló, Arnau, Carbonell, Teresa, Bardallo, Raquel G., Teixeira da Silva, Rui, Roselló-Catafau, Joan   +5 more
core   +1 more source