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Organ Transplantation [PDF]

The Lancet, 1968
BRUNO J. URBAN
openalex   +4 more sources

Macrophages in Organ Transplantation [PDF]

Frontiers in Immunology, 2020
Current immunosuppressive therapy has led to excellent short-term survival rates in organ transplantation. However, long-term graft survival rates are suboptimal, and a vast number of allografts are gradually lost in the clinic. An increasing number of animal and clinical studies have demonstrated that monocytes and macrophages play a pivotal role in ...
Farideh Ordikhani, Rodrigo Sanchez-Tarjuelo, Venu Pothula, Jordi Ochando, Jordi Ochando, Stefan Jordan   +5 more
openaire   +4 more sources

Expert consensus on clinical trials of human xenotransplantation in China

Health Care Science, 2022
The history of xenotransplantation started in the 19th century. After a few decades of investigation, significant breakthroughs and preclinical milestones have been achieved worldwide.
Jiefu Huang, China Organ Transplantation Development Foundation   +1 more
doaj   +1 more source

Continuous Renal Replacement Therapy in Pediatric Patients With Acute Kidney Injury After Liver Transplantation

Frontiers in Pediatrics, 2022
ObjectiveThis study aimed to explore the clinical application of continuous renal replacement therapy (CRRT) in pediatric patients with acute kidney injury (AKI) after liver transplantation.MethodsPediatric patients who underwent liver transplantation ...
Yan Sun, Yan Sun, Sinan Gao, Sinan Gao, Xingqiang Wang, Xingqiang Wang, Lixin Yu, Lixin Yu, Min Xu, Min Xu, Wei Gao, Wei Gao, Chao Sun, Chao Sun, Bing Wang, Bing Wang   +15 more
doaj   +1 more source

A Transformer-Based Deep Learning Approach for Fairly Predicting Post-Liver Transplant Risk Factors [PDF]

J Biomed Inform. 2024 Jan;149:104545, 2023
Liver transplantation is a life-saving procedure for patients with end-stage liver disease. There are two main challenges in liver transplant: finding the best matching patient for a donor and ensuring transplant equity among different subpopulations. The current MELD scoring system evaluates a patient's mortality risk if not receiving an organ within ...
arxiv   +1 more source

L-carnitine promotes liver regeneration after hepatectomy by enhancing lipid metabolism

Journal of Translational Medicine, 2023
Background Lipid metabolism plays an important role in liver regeneration, but its regulation still requires further research. In this study, lipid metabolites involved in mouse liver regeneration at different time points were sequenced and analyzed to ...
Xi Zhou, Guobin Huang, Lu Wang, Yuanyuan Zhao, Junbo Li, Dong Chen, Lai Wei, Zhishui Chen, Bo Yang   +8 more
doaj   +1 more source

Sirolimus in combination with low-dose extended-release tacrolimus in kidney transplant recipients

Frontiers in Medicine, 2023
IntroductionMany challenges remain for long-term survival of renal allografts. Once-daily sirolimus (SRL) combined with low-dose extended-release tacrolimus (LER-TAC) may improve medication adherence and reduce the potential nephrotoxicity of calcineurin
Zhi-yu Zou, Lin-rui Dai, Yi-bo Hou, Chen-zhen Yu, Ren-jie Chen, Yan-yan Chen, Bin Liu, Hui-bo Shi, Nian-qiao Gong, Zhi-shui Chen, Song Chen, Sheng Chang, Wei-jie Zhang   +12 more
doaj   +1 more source

Impact of donor age on short-term outcomes after pediatric split liver transplantation

Frontiers in Pediatrics, 2023
BackgroundDonor shortage is an important limitation of liver transplantation (LT). Split liver transplantation (SLT) may increase the sources of donors and reduce the problem of organ shortage.
Min Xu, Min Xu, Chong Dong, Chong Dong, Chao Sun, Chao Sun, Kai Wang, Kai Wang, Wei Zhang, Wei Zhang, Hong Qin, Hong Qin, Chao Han, Chao Han, Yang Yang, Yang Yang, Fubo Zhang, Fubo Zhang, Zhen Wang, Zhen Wang, Weiping Zheng, Weiping Zheng, Xinzhe Wei, Xinzhe Wei, Wei Gao, Wei Gao, Zhongyang Shen, Zhongyang Shen   +27 more
doaj   +1 more source

Bioinformatics analyses on the immune status of renal transplant patients, a systemic research of renal transplantation

BMC Medical Genomics, 2020
Background Kidney transplantation is the most effective treatment for end-stage renal disease. Allograft rejections severely affect survivals of allograft kidneys and recipients.
Mei Meng, Weitao Zhang, Qunye Tang, Baixue Yu, Tingting Li, Ruiming Rong, Tongyu Zhu, Ming Xu, Yi Shi   +8 more
doaj   +1 more source

Liraglutide Attenuates Hepatic Ischemia–Reperfusion Injury by Modulating Macrophage Polarization

Frontiers in Immunology, 2022
Ischemia-reperfusion injury (IRI) is a common complication associated with liver surgery, and macrophages play an important role in hepatic IRI. Liraglutide, a glucagon-like peptide-1 (GLP-1) analog primarily used to treat type 2 diabetes and obesity ...
Shang-Lin Li, Shang-Lin Li, Zhi-Min Wang, Cong Xu, Cong Xu, Fu-Heng Che, Fu-Heng Che, Xiao-Fan Hu, Xiao-Fan Hu, Rui Cao, Rui Cao, Ya-Nan Xie, Ya-Nan Xie, Yang Qiu, Yang Qiu, Hui-Bo Shi, Hui-Bo Shi, Bin Liu, Bin Liu, Chen Dai, Chen Dai, Jun Yang, Jun Yang   +22 more
doaj   +1 more source