Results 1 to 10 of about 2,364,274 (318)

Activation of immune signals during organ transplantation

Signal Transduction and Targeted Therapy, 2023
The activation of host’s innate and adaptive immune systems can lead to acute and chronic graft rejection, which seriously impacts graft survival. Thus, it is particularly significant to clarify the immune signals, which are critical to the initiation ...
Qingwen Li, P. Lan
semanticscholar   +1 more source

The Global Impact of COVID-19 on Solid Organ Transplantation: Two Years Into a Pandemic

Transplantation, 2022
The coronavirus disease 2019 (COVID-19) pandemic has had a major global impact on solid organ transplantation (SOT). An estimated 16% global reduction in transplant activity occurred over the course of 2020, most markedly impacting kidney transplant and ...
A. Nimmo, D. Gardiner, I. Ushiro‐Lumb, R. Ravanan, J. Forsythe   +4 more
semanticscholar   +1 more source

Gut microbiome dysbiosis is associated with increased mortality after solid organ transplantation

Science Translational Medicine, 2022
Organ transplantation is a life-saving treatment for patients with end-stage disease, but survival rates after transplantation vary considerably. There is now increasing evidence that the gut microbiome is linked to the survival of patients undergoing ...
J. C. Swarte, Yanni Li, Shixian Hu, J. Björk, R. Gacesa, A. Vich Vila, R. Douwes, V. Collij, A. Kurilshikov, A. Post, M. Klaassen, M. Eisenga, A. Gomes-Neto, D. Kremer, B. Jansen, T. Knobbe, S. Berger, J. Sanders, M. Heiner-Fokkema, R. Porte, F. Cuperus, V. D. de Meijer, C. Wijmenga, E. Festen, A. Zhernakova, Jingyuan Fu, H. Harmsen, H. Blokzijl, S. Bakker, R. Weersma   +29 more
semanticscholar   +1 more source

Expert consensus on clinical trials of human xenotransplantation in China

Health Care Science, 2022
The history of xenotransplantation started in the 19th century. After a few decades of investigation, significant breakthroughs and preclinical milestones have been achieved worldwide.
Jiefu Huang, China Organ Transplantation Development Foundation   +1 more
doaj   +1 more source

Grand Challenges in Organ Transplantation

Frontiers in Transplantation, 2022
The modern era of organ transplantation was pioneered at the Peter Bent Brigham Hospital in Boston by physician-scientists John P. Merrill (nephrologist), and Joseph E. Murray (surgeon).
J. Kupiec-Weglinski
semanticscholar   +1 more source

The Unique Immunomodulatory Properties of MSC-Derived Exosomes in Organ Transplantation

Frontiers in Immunology, 2021
Methods for suppressing the host immune system over the long term and improving transplantation tolerance remain a primary issue in organ transplantation.
Qingyuan Zheng, Shuijun Zhang, Wenzhi Guo, Xiao‐Kang Li   +3 more
semanticscholar   +1 more source

Continuous Renal Replacement Therapy in Pediatric Patients With Acute Kidney Injury After Liver Transplantation

Frontiers in Pediatrics, 2022
ObjectiveThis study aimed to explore the clinical application of continuous renal replacement therapy (CRRT) in pediatric patients with acute kidney injury (AKI) after liver transplantation.MethodsPediatric patients who underwent liver transplantation ...
Yan Sun, Yan Sun, Sinan Gao, Sinan Gao, Xingqiang Wang, Xingqiang Wang, Lixin Yu, Lixin Yu, Min Xu, Min Xu, Wei Gao, Wei Gao, Chao Sun, Chao Sun, Bing Wang, Bing Wang   +15 more
doaj   +1 more source

L-carnitine promotes liver regeneration after hepatectomy by enhancing lipid metabolism

Journal of Translational Medicine, 2023
Background Lipid metabolism plays an important role in liver regeneration, but its regulation still requires further research. In this study, lipid metabolites involved in mouse liver regeneration at different time points were sequenced and analyzed to ...
Xi Zhou, Guobin Huang, Lu Wang, Yuanyuan Zhao, Junbo Li, Dong Chen, Lai Wei, Zhishui Chen, Bo Yang   +8 more
doaj   +1 more source

Covid-19 and Solid Organ Transplantation: A Review Article.

Transplantation, 2020
The coronavirus pandemic has significantly impacted solid organ transplantation (SOT). Early in the outbreak period, transplant societies recommended suspending living kidney transplant programs in communities with widespread transmission to avoid ...
Y. Azzi, Rachel Bartash, J. Scalea, P. Loarte-Campos, E. Akalin   +4 more
semanticscholar   +1 more source

Bioinformatics analyses on the immune status of renal transplant patients, a systemic research of renal transplantation

BMC Medical Genomics, 2020
Background Kidney transplantation is the most effective treatment for end-stage renal disease. Allograft rejections severely affect survivals of allograft kidneys and recipients.
Mei Meng, Weitao Zhang, Qunye Tang, Baixue Yu, Tingting Li, Ruiming Rong, Tongyu Zhu, Ming Xu, Yi Shi   +8 more
doaj   +1 more source