Results 101 to 110 of about 2,489,307 (382)

Biomimetic Nanomedicines Deliver Naringin for Enhanced Acute Liver Failure Therapy via Balanced Regulation of Hepatocyte Oxidative Stress and Kupffer Cell Inflammation

open access: yesAdvanced Functional Materials, EarlyView.
A biomimetic nanomedicine (RBLN) constructed by loading natural antioxidants to clinically used layered double hydroxide nanoparticles is surface coated with fresh or senescent red blood cell membrane for balanced drug delivery to hepatocytes and KCs, thereby simultaneously alleviating liver oxidant stress and inflammation for effective drug‐induced ...
Jiahui Shao   +8 more
wiley   +1 more source

Organ transplantation--then and now. [PDF]

open access: yes, 1987
The last 25 years have seen amazing progress in transplantation--from the development of techniques for immunosuppression to methods for organ removal and preservation.
Makowka, L, Starzl, TE
core  

Induction of donor-specific transplantation tolerance to skin and cardiac allografts using mixed chimerism in (A + B → A) in rats [PDF]

open access: yes, 1993
Mixed allogeneic chimerism (A + B → A) was induced in rats by reconstitution of lethally irradiated LEW recipients with a mixture of T-cell depleted (TCD) syngeneic and TCD allogeneic ACI bone marrow. Thirty-seven percent of animals repopulated as stable
Cai, X   +4 more
core   +1 more source

Outcomes in Solid-Organ Transplantation: Success and Stagnation.

open access: yesTexas Heart Institute Journal, 2019
S ince emerging as a f ield in the 1980s, solid-organ transplantation has progressed rapidly, enabled by advances in immunosuppression, imaging methods, antimicrobial agents, and donor–recipient matching.
Abbas Rana, E. Godfrey
semanticscholar   +1 more source

Transmembrane Activation of Catalysis and Protein Refolding in Synthetic Cells by Enzymes and Nanozymes

open access: yesAdvanced Functional Materials, EarlyView.
Synthetic cells are engineered herein to respond to an external chemical messenger by the activation of intracellular catalysis. The chemical messenger molecules are catalytically generated by an extracellular enzyme or a mineral surface, whereas the intracellular catalysis emerges via direct enzyme activation or via protein refolding.
Dante G. Andersen   +5 more
wiley   +1 more source

Perioperative factors associated with survival following surgery for pancreatic cancer – a nationwide analysis of 473 cases from Denmark.

open access: yesBMC Surgery
Background Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal cancers worldwide, with an overall 5-year survival rate of only 5%. The effect of perioperative treatment factors including duration of surgery, blood transfusions as well ...
Laura Marr Spore   +8 more
doaj   +1 more source

Transplantation tolerance from a historical perspective [PDF]

open access: yes, 2001
Although transplantation immunology as a distinctive field began with the development of experimental models that showed the feasibility of bone marrow transplantation, organ engraftment was accomplished first in humans, and was thought for many years to
Starzl, TE, Zinkernagel, RM
core   +1 more source

The past, present, and future of costimulation blockade in organ transplantation.

open access: yesCurrent Opinion in Organ Transplantation, 2019
PURPOSE OF REVIEW Manipulating costimulatory signals has been shown to alter T cell responses and prolong graft survival in solid organ transplantation.
P. Schroder   +5 more
semanticscholar   +1 more source

Anionic Citrate‐Based 3D‐Printed Scaffolds for Tunable and Sustained Orthobiologic Delivery to Enhance Tissue Regeneration

open access: yesAdvanced Functional Materials, EarlyView.
A potent anionic citric acid‐based 3D‐printed scaffold is developed for the sustained and controlled release of orthobiologics to enhance orthopedic therapeutic efficacy. Comprehensive in vivo studies demonstrated effective bone fusion and high safety at a low dose of BMP‐2 delivered by the system, establishing it as a promising platform for safe ...
Se‐Hwan Lee   +12 more
wiley   +1 more source

Organ Entrepreneurs [PDF]

open access: yes, 2017
The supply of human organs for transplantation might seem an unlikely place to begin thinking about entrepreneurship. After all, there is no production market for human organs and, with the surprising exception of Iran, legal rules around the world make ...
Healy, Kieran, Krawiec, Kimberly D.
core   +2 more sources

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