Results 21 to 30 of about 2,364,274 (318)

In vivo therapeutic potential of Inula racemosa in hepatic ischemia–reperfusion injury following orthotopic liver transplantation in male albino rats

AMB Express, 2017
Hepatic ischemia–reperfusion (I/R) injury mainly occurs following hepatic resection and liver transplantation and cause severe liver damage, organ injuries, and dysfunction.
Zhuoyi Wang, Lei Geng, Zhiyun Chen, Bingyi Lin, Mangli Zhang, Shusen Zheng   +5 more
doaj   +1 more source

TJ-M2010-5, a novel CNS drug candidate, attenuates acute cerebral ischemia-reperfusion injury through the MyD88/NF-κB and ERK pathway

Frontiers in Pharmacology, 2022
Background: Cerebral ischemia-reperfusion injury (CIRI) inevitably occurs after vascular recanalization treatment for ischemic stroke. The accompanying inflammatory cascades have a major impact on outcome and regeneration after ischemic stroke. Evidences
Zeyang Li, Zeyang Li, Minghui Zhao, Minghui Zhao, Xiaoqian Zhang, Yiran Lu, Yang Yang, Yang Yang, Yalong Xie, Yalong Xie, Zhimiao Zou, Zhimiao Zou, Liang Zhou, Liang Zhou, Runshi Shang, Runshi Shang, Limin Zhang, Limin Zhang, Fengchao Jiang, Dunfeng Du, Dunfeng Du, Ping Zhou, Ping Zhou   +22 more
doaj   +1 more source

Organ Procurement and Transplantation Network

Definitions, 2020
Description: The only national patient waiting list and an online database system, called UNet, that links all of the professionals involved in the donation and transplantation system for the collection, storage, analysis, and publication of all OPTN ...

semanticscholar   +1 more source

Cytomegalovirus in solid organ transplant recipients—Guidelines of the American Society of Transplantation Infectious Diseases Community of Practice

Clinical Transplantation, 2019
Cytomegalovirus (CMV) is one of the most common opportunistic infections that affect the outcome of solid organ transplantation. This updated guideline from the American Society of Transplantation Infectious Diseases Community of Practice provides ...
R. Razonable, A. Humar
semanticscholar   +1 more source

Value of blood lipid in predicting graft dysfunction after organ and tissue transplantation: A study of Mendelian randomization

Heliyon, 2023
Background: While immunosuppressive regimens have improved outcomes in solid organ transplantation, non-immune factors have also been identified as contributors to graft prognosis.
Yuanyuan Zhao, Dunfeng Du, Lai Wei, Zhishui Chen   +3 more
doaj   +1 more source

Banff 2019 Meeting Report: Molecular diagnostics in solid organ transplantation–Consensus for the Banff Human Organ Transplant (B‐HOT) gene panel and open source multicenter validation

American Journal of Transplantation, 2020
This meeting report from the XV Banff conference describes the creation of a multiorgan transplant gene panel by the Banff Molecular Diagnostics Working Group (MDWG).
M. Mengel, A. Loupy, M. Haas, C. Roufosse, M. Naesens, E. Akalin, M. C. Clahsen‐van Groningen, Jessy Dagobert, A. Demetris, J. Duong van Huyen, Juliette Gueguen, F. Issa, B. Robin, I. Rosales, J. H. von der Thüsen, A. Sánchez‐Fueyo, R. Smith, K. Wood, B. Adam, R. Colvin   +19 more
semanticscholar   +1 more source

The COVID-19 outbreak in Italy: Initial implications for organ transplantation programs

American Journal of Transplantation, 2020
The spread of Coronavirus Disease 2019 (COVID‐19) has already reached a pandemic dimension within a few weeks. Italy has been one of the first countries dealing with the outbreak of COVID‐19, and severe measures have been adopted to limit viral ...
R. Angelico, S. Trapani, T. Manzia, L. Lombardini, G. Tisone, M. Cardillo   +5 more
semanticscholar   +1 more source

RNA interference therapeutics in organ transplantation: The dawn of a new era

American Journal of Transplantation, 2020
RNA interference (RNAi) is a natural process through which double‐stranded RNA molecules can silence the gene carrying the same code as the particular RNA of interest. In 2006, the discovery of RNAi was awarded the Nobel Prize in Medicine and its success
I. Brüggenwirth, P. Martins
semanticscholar   +1 more source

Identification of the Subtypes of Renal Ischemia-Reperfusion Injury Based on Pyroptosis-Related Genes

Biomolecules, 2023
Ischemia-reperfusion injury (IRI) often occurs in the process of kidney transplantation, which significantly impacts the subsequent treatment and prognosis of patients.
Xinhao Niu, Yin Celeste Cheuk, Xiao Li, Ruiming Rong, Xiaoqing Xu, Cuidi Xu, Yongsheng Luo, Pingbao Zhang, Jingjing Guo   +8 more
doaj   +1 more source

Heme oxygenase-1-transduced bone marrow mesenchymal stem cells in reducing acute rejection and improving small bowel transplantation outcomes in rats

Stem Cell Research & Therapy, 2016
Background We determined whether bone marrow mesenchymal stem cells (BMMSCs) transduced with heme oxygenase-1 (HO-1), a cytoprotective and immune-protective factor, could improve outcomes for small bowel transplantation (SBTx) in rats.
Yang Yang, Hong Li Song, Wen Zhang, Ben Juan Wu, Nan Nan Fu, Chong Dong, Zhong Yang Shen   +6 more
doaj   +1 more source