Results 141 to 150 of about 110,333 (306)

Sex differences in hepatic enzymes and transporters involved in pharmacokinetics

Liver Research
Females experience adverse drug reactions at approximately twice the rate of males, contributing to drug-related morbidity and mortality in the United States.
Mehak Behal, Zachary McCalla, Xinwen Wang   +2 more
doaj   +1 more source

The Role of Organic Cation Transporters in the Pharmacokinetics, Pharmacodynamics and Drug-Drug Interactions of Tyrosine Kinase Inhibitors. [PDF]

Int J Mol Sci, 2023
Xiu F, Rausch M, Gai Z, Su S, Wang S, Visentin M.   +5 more
europepmc   +1 more source

Transient Charging of Mixed Ionic‐Electronic Conductors by Anomalous Diffusion

Advanced Materials, EarlyView.
This article explores charge transport in mixed ionic‐electronic conductors (MIECs) through electrochemical impedance spectroscopy and transient current analysis. Focusing on PEDOT:PSS, WO3, and n‐doped PBDF, it uncovers the impact of anomalous diffusion via fractional modeling. The study reveals key correlations that deepen understanding and guide the
Heyi Zhang, Gonzalo Rivera‐Sierra, Shirin Siahjani‐Gultekin, Jenifer Rubio‐Magnieto, Anis Allagui, Ignacio Sanjuán, David Franco, Antonio Guerrero, Enrique H. Balaguera, Juan Bisquert   +9 more
wiley   +1 more source

Pharmacological and physiological characteristics of organic cation transporters (OCTs) and multidrug and toxin extrusion proteins (MATEs)

, 2013
Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Pharmacology and Toxicology Student: Pavla Gregorová Supervisor: Prof. PharmDr. František Štaud, Ph.D.
Gregorová, Pavla
core  

Supplementary Tables 1-3 from Interactions of Tyrosine Kinase Inhibitors with Organic Cation Transporters and Multidrug and Toxic Compound Extrusion Proteins

, 2011
Supplementary Tables 1-3 from Interactions of Tyrosine Kinase Inhibitors with Organic Cation Transporters and Multidrug and Toxic Compound Extrusion ...
Kathleen M. Giacomini (259990), Tsuyoshi Minematsu (15065071)   +1 more
core   +1 more source

Amino Acid-Responsive Crohn’s Disease: A Case Study [Retraction]

Clinical and Experimental Gastroenterology, 2020
Stein A, Hinz M, Uncini T. Clin Exp Gastroenterol. 2010;3:171–177. The Editor-in-chief and Publisher of Clinical and Experimental Gastroenterology wish to retract the published article.
Stein A, Hinz M, Uncini T
doaj  

Targeting organic cation transporters at the blood-brain barrier to treat ischemic stroke in rats. [PDF]

Exp Neurol, 2022
Stanton JA, Williams EI, Betterton RD, Davis TP, Ronaldson PT.   +4 more
europepmc   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Expression, regulation and substrate specificity of organic cation transporters in human renal cell systems

, 2006
Active uptake of the organic cation, tetraethylammonium (TEA), was shown in freshly isolated human and rat PT cells.  This uptake was both inhibitable and temperature dependent.
Duffy, Kevin
core  

Amino Acid-Responsive Crohn’s Disease: A Case Study [Expression of Concern]

Clinical and Experimental Gastroenterology, 2020
Stein A, Hinz M, Uncini T. Clin Exp Gastroenterol.  2010;3:171– 177. The Editor-in-Chief and Publisher of Clinical and Experimental Gastroenterology wish to issue an Expression of Concern for the published article. Concerns have been
Stein A, Hinz M, Uncini T
doaj