Results 91 to 100 of about 754,218 (305)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
A screening method for ranking chemicals by their fate and behaviour in the environment and potential toxic effects in humans following non-occupational exposure [PDF]
, 2004 A large number of chemicals are released intentionally or unintentionally into the environment each year. These include thousands of substances that are currently listed worldwide and several hundred new substances added annually (Mücke et al., 1986 ...
Capelton, A +2 more
core
, 2011 Soil contamination occurs when substances are added to soil, resulting in increases in concentrations above background or reference levels. Pollution may follow from contamination when contaminants are present in amounts that are detrimental to soil ...
Bacon, J. +7 more
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Exploring the organic agriculture practice in Mexico: an opportunity for small-scale farmers to feed themselves [PDF]
We examine how organic farming practiced by small farmers in rural zones in Mexico could build a self-sufficient food system. We hold the hypothesis that the promotion of the local consumption of organic produce is an alternative to strengthen the local ...
Hernandez Cervantes, Tania +1 more
core +1 more source
Evaluation of Fungal Metabolic Compounds Released to the Air in a Restricted Environment [PDF]
, 1991 The metabolic action of selected fungi species on common components of the interior of Space Station Freedom (SSF) will be tested. When present, volatile organic chemicals will be collected on porous polymer adsorbent columns.
Ferebee, Robert N.
core +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Nitrogen Organic Compounds: Emergent Chemicals in Landfill Leachate
Chemical Engineering Transactions, 2010 preview not available - see full-text PDF article.
E. Lovatel +2 more
doaj +1 more source