Results 71 to 80 of about 754,218 (305)

Nanoparticles modified screen printed electrode for electrochemical determination of COD [PDF]

open access: yes, 2015
The Chemical Oxygen Demand (COD) is a parameter widely used to determine organic pollutants in water and is defined as the number of oxygen equivalents necessary to oxidize the organic compounds.
Antonella De Mico   +7 more
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Reductive defluorination of aqueous perfluorinated alkyl surfactants : effects of ionic headgroup and chain length [PDF]

open access: yes, 2009
Perfluorinated chemicals (PFCs) are distributed throughout the environment. In the case of perfluorinated alkyl carboxylates and sulfonates, they can be classified as persistent organic pollutants since they are resistant to environmentally relevant ...
Cheng, Jie   +5 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Recognition and Sequencing of Mutagenic DNA Adduct at Single‐Base Resolution Through Unnatural Base Pair

open access: yesAdvanced Science
DNA lesions are linked to cancer, aging, and various diseases. The recognition and sequencing of special DNA lesions are of great interest but highly challenging.
Honglei Wang   +8 more
doaj   +1 more source

Global Contamination Trends of Persistent Organic Chemicals [PDF]

open access: yes, 2012
Environmental pollution by man-made persistent organic chemicals (POCs) has been a serious global issue for over half a century. Exposure to certain POCs may result in environmental and health effects including skin disorders, liver damage, birth defects,
Lam, Paul K.S.   +1 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Influence of management practices on quality and biodiversity of tomatoes in Germany [PDF]

open access: yes, 2005
Four old and endangered tomato cultivars were cultivated under greenhouse conditions with different levels of organic N-fertilisation and harvest at different maturity stages in order to develop a conclusive concept to preserve the diversity of old ...
Klein, Daniela   +2 more
core  

Atmospheric pressure gas chromatography-time-of-flight-mass spectrometry (APGC-ToF-MS) for the determination of regulated and emerging contaminants in aqueous samples after stir bar sorptive extraction (SBSE) [PDF]

open access: yes, 2014
This work presents the development, optimization and validation of a multi-residue method for the simultaneous determination of 102 contaminants, including fragrances, UV filters, repellents, endocrine disruptors, biocides, polycyclic aromatic ...
Arbulu   +38 more
core   +2 more sources

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